Kisspeptin-54 (human) (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Kisspeptin-54 (human) (trifluoroacetate salt)
- Synonyms
- Kisspeptin-54 (human) (trifluoroacetate salt)
- CBNumber:
- CB44814768
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Kisspeptin-54 (human) (trifluoroacetate salt) price More Price(1)
Kisspeptin-54 (human) (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
Kisspeptin-54 is a peptide ligand of the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors, respectively). It is a 54 amino acid peptide encoded by the metastasis suppressor gene KISS-1. Kisspeptin-54 induces calcium mobilization in CHO-K1 cells expressing rat and human receptors (EC50s = 1.39 and 5.47 nM, respectively). It also induces arachidonic acid release in CHO cells expressing rat and human GPR54 in a concentration-dependent manner. Kisspeptin-54 (10-1,000 nM) inhibits insulin secretion from isolated mouse pancreatic β-cells in the presence of 2.8 mM, but not 11.1 mM, glucose. Kisspeptin-54 (1-5 nmol, i.c.v.) increases serum levels of luteinizing hormone (LH) and follicular stimulating hormone (FSH) in mice, an effect which is reversed by the gonadotropin releasing hormone (GNRH) antagonist acycline.
References
[1] M. KOTANI. The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54*[J]. The Journal of Biological Chemistry, 2001, 1 1: 34631-34636. DOI: 10.1074/jbc.m104847200
[2] J. VIKMAN B. A. Inhibitory effect of kisspeptins on insulin secretion from isolated mouse islets[J]. Diabetes, Obesity & Metabolism, 2009, 11 s4: 197-201. DOI: 10.1111/j.1463-1326.2009.01116.x
[3] M L GOTTSCH. A role for kisspeptins in the regulation of gonadotropin secretion in the mouse.[J]. Endocrinology, 2004, 145 9: 4073-4077. DOI: 10.1210/en.2004-0431
Kisspeptin-54 (human) (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Kisspeptin-54 (human) (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
View Latest Price from Kisspeptin-54 (human) (trifluoroacetate salt) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-05 | Kisspeptin-54 (human) (trifluoroacetate salt) | $2320.00 | 10g | TargetMol Chemicals Inc. |
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- Kisspeptin-54 (human) (trifluoroacetate salt)
- $2320.00
- TargetMol Chemicals Inc.
