α-Bungarotoxin (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- α-Bungarotoxin (trifluoroacetate salt)
- Synonyms
- α-Bungarotoxin (trifluoroacetate salt)
- CBNumber:
- CB44815376
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
α-Bungarotoxin (trifluoroacetate salt) price More Price(1)
α-Bungarotoxin (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
α-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis.1,2,3 It has been widely used to characterize activity at the neuromuscular junction, which has numerous applications in neuroscience research.4,5WARNING This product is not for human or veterinary use.
References
[1] J P CHANGEUX C Y L M Kasai. Use of a snake venom toxin to characterize the cholinergic receptor protein.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1970, 67 3: 1241-1247. DOI: 10.1073/pnas.67.3.1241
[2] A G MUKHIN. 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.[J]. Molecular Pharmacology, 2000, 57 3: 642-649. DOI: 10.1124/mol.57.3.642
[3] J J PLOMP P C M. Involvement of protein kinases in the upregulation of acetylcholine release at endplates of alpha-bungarotoxin-treated rats.[J]. Journal of Physiology-London, 1996, 493 1: 175-186. DOI: 10.1113/jphysiol.1996.sp021373
[4] SHARON R. GRADY . The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum[J]. Biochemical pharmacology, 2007, 74 8: Pages 1235-1246. DOI: 10.1016/j.bcp.2007.07.032
[5] SELVANAYAGAM NIRTHANAN Matthew C E G. Three-Finger α-Neurotoxins and the Nicotinic Acetylcholine Receptor, Forty Years On[J]. Journal of pharmacological sciences, 2004, 94 1: Pages 1-17. DOI: 10.1254/jphs.94.1
α-Bungarotoxin (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
α-Bungarotoxin (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
