IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE
- CAS No.
- 6188-43-8
- Chemical Name:
- IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE
- Synonyms
- Minodronic Acid Impurity 30;[1,2-α]PYRIDIN-3-CARBOXALDEHYDE;Imidazo[1,2-a]pyridine-3-carbaldehyde;imidazo[3,2-a]pyridine-3-carbaldehyde;3-imidazo[3,2-a]pyridinecarboxaldehyde;IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE;IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE;Imidazo[1,2-a]pyridine-3-carbaldehyde AldrichCPR;Imidazo[1,2-a]pyridine-3-carboxaldehyde (7CI, 8CI, 9CI, ACI)
- CBNumber:
- CB4483670
- Molecular Formula:
- C8H6N2O
- Molecular Weight:
- 146.15
- MDL Number:
- MFCD07778354
- MOL File:
- 6188-43-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Imidazo[1,2-a]pyridine-3-carbaldehyde | I387593 | 500mg | $175 |
| Imidazo[1,2-a]pyridine-3-carbaldehyde | 040365 | 500mg | $252 |
| Imidazo[1,2-a]pyridine-3-carbaldehyde 98% | OR909920 | 5g | $330 |
| Imidazo[1,2-a]pyridine-3-carbaldehyde 98% | OR909920 | 10g | $565 |
| Imidazo[1,2-a]pyridine-3-carbaldehyde 98% | OR909920 | 1g | $115 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HazardClass | IRRITANT |
| HS Code | 2933998090 |
IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | I387593 | Imidazo[1,2-a]pyridine-3-carbaldehyde | 6188-43-8 | 500mg | $175 | 2021-12-16 | Buy |
| Matrix Scientific | 040365 | Imidazo[1,2-a]pyridine-3-carbaldehyde | 6188-43-8 | 500mg | $252 | 2021-12-16 | Buy |
| Apolloscientific | OR909920 | Imidazo[1,2-a]pyridine-3-carbaldehyde 98% | 6188-43-8 | 5g | $330 | 2021-12-16 | Buy |
| Apolloscientific | OR909920 | Imidazo[1,2-a]pyridine-3-carbaldehyde 98% | 6188-43-8 | 10g | $565 | 2021-12-16 | Buy |
| Apolloscientific | OR909920 | Imidazo[1,2-a]pyridine-3-carbaldehyde 98% | 6188-43-8 | 1g | $115 | 2021-12-16 | Buy |
IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE Chemical Properties,Uses,Production
Synthesis
274-76-0
68-12-2
6188-43-8
Freshly distilled phosphorus trichloride (61 mL, 0.65 mol) was slowly added to N,N-dimethylformamide (120 mL, 1.55 mol) at 2 °C. After controlling the reaction temperature to gradually increase to room temperature, the reaction system was again cooled to 2 °C. Subsequently, a solution of N,N-dimethylformamide (60 mL) of imidazo[1,2-a]pyridine (10 g, 0.085 mol) was added dropwise. The reaction mixture was slowly warmed to 105 °C, followed by further warming to 140 °C. The reaction temperature was stabilized at 120 °C by removing the oil bath. Heating was continued at this temperature for 45 minutes, after which the temperature was reduced to 85 °C and continued for 2.5 hours. Upon completion of the reaction, the mixture was cooled and poured into ice-cooled 5% hydrochloric acid (600 mL) and the pH was adjusted with 20% sodium hydroxide solution to 9. The resulting solution was extracted with dichloromethane (1200 mL) overnight. The organic layer was separated, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was washed with water (5 x 15 mL) and dried again to give 3.49 g of imidazo[1,2-a]pyridine-3-carbaldehyde in 31% yield.
References
[1] Farmaco, Edizione Scientifica, 1981, vol. 36, # 12, p. 994 - 1003
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 9, p. 3454 - 3464
[3] European Journal of Medicinal Chemistry, 2011, vol. 46, # 10, p. 4820 - 4826
[4] Journal of Medicinal Chemistry, 1996, vol. 39, # 14, p. 2856 - 2859
[5] Patent: WO2005/66132, 2005, A1. Location in patent: Page/Page column 89-90
IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16516 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14360 | 58 |
View Lastest Price from IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-10-13 | Imidazo[1,2-a]pyridine-3-carbaldehyde
6188-43-8
|
US $1.60-6.60 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
![]() |
2020-01-10 | IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE
6188-43-8
|
US $1.00 / g | 1g | 99.0% | 100kg | Career Henan Chemical Co |
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![Imidazo[1,2-a]pyridine-3-carbaldehyde pictures](/ProductImageEN1/2025-06/Small/62df2e5b-1141-4072-b23d-3c4133e5b630.png)
- Imidazo[1,2-a]pyridine-3-carbaldehyde
6188-43-8
- US $1.60-6.60 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
![IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/7d9e8fe3-6656-4e33-8661-209b356ffa5d.png)
- IMIDAZO[1,2-A]PYRIDIN-3-CARBOXALDEHYDE
6188-43-8
- US $1.00 / g
- 99.0%
- Career Henan Chemical Co
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