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GSK2894631A

GSK2894631A Structure
GSK2894631A structure
CAS No.
2101626-26-8
Chemical Name:
GSK2894631A
Synonyms
GSK2894631A;HPGDS inhibitor 2;GSK-2894631A(HPGDS inhibitor 2);HPGDS inhibitor 2, 10 mM in DMSO;7-(Difluoromethoxy)-N-(trans-4-(2-hydroxypropan-2-yl)cyclohexyl)quinoline-3-carboxamide;7-(difluoromethoxy)-N-[(1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl]quinoline-3-carboxamide;7-(Difluoromethoxy)- N-[trans-4-(1-hydroxy-1-methylethyl)cyclohexyl]-3-quinolinecarboxamide;3-Quinolinecarboxamide, 7-(difluoromethoxy)-N-[trans-4-(1-hydroxy-1-methylethyl)cyclohexyl]-;HPGDS inhibitor2,PGE synthase,Inhibitor,inhibit,HPGDS inhibitor-2,HPGDS inhibitor 2,Prostaglandin E synthase
CBNumber:
CB44882154
Molecular Formula:
C20H24F2N2O3
Molecular Weight:
378.41
MDL Number:
MOL File:
2101626-26-8.mol
Last updated:2025-04-18 09:52:21
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GSK2894631A Properties

Boiling point 572.5±45.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. 4°C, away from moisture and light
solubility DMSO:150.0(Max Conc. mg/mL);396.39(Max Conc. mM)
form Solid
pka 13.22±0.40(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

GSK2894631A price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0090737 HPGDSinhibitor2 99.79% 2101626-26-8 5mg $350 2021-12-16 Buy
ChemScene CS-0090737 HPGDSinhibitor2 99.79% 2101626-26-8 10mg $550 2021-12-16 Buy
Biorbyt Ltd orb573475 GSK-2894631A >98% 2101626-26-8 100mg $1133.9 2021-12-16 Buy
ChemScene CS-0090737 HPGDSinhibitor2 99.79% 2101626-26-8 50mg $1650 2021-12-16 Buy
Biorbyt Ltd orb573475 GSK-2894631A >98% 2101626-26-8 250mg $2097.8 2021-12-16 Buy
Product number Packaging Price Buy
CS-0090737 5mg $350 Buy
CS-0090737 10mg $550 Buy
orb573475 100mg $1133.9 Buy
CS-0090737 50mg $1650 Buy
orb573475 250mg $2097.8 Buy

GSK2894631A Chemical Properties,Uses,Production

Uses

HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM[1].

References

[1] Deaton DN, et al. The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1456-1478. DOI:10.1016/j.bmc.2019.02.017

GSK2894631A Preparation Products And Raw materials

Raw materials

Preparation Products

GSK2894631A Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30230 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4611 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Career Henan Chemica Co 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62

2101626-26-8(GSK2894631A)Related Search:

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GSK2982772 GSK-2881078 N-(4-ethylphenyl)-3-(hydroxymethyl)-N-isobutyl-4-((tetrahydro-2H-pyran-4-yl)methoxy)benzenesulfonamide GSK3145095 GSK3039294

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HPGDS inhibitor 2 GSK2894631A 3-Quinolinecarboxamide, 7-(difluoromethoxy)-N-[trans-4-(1-hydroxy-1-methylethyl)cyclohexyl]- 7-(Difluoromethoxy)- N-[trans-4-(1-hydroxy-1-methylethyl)cyclohexyl]-3-quinolinecarboxamide HPGDS inhibitor2,PGE synthase,Inhibitor,inhibit,HPGDS inhibitor-2,HPGDS inhibitor 2,Prostaglandin E synthase GSK-2894631A(HPGDS inhibitor 2) 7-(Difluoromethoxy)-N-(trans-4-(2-hydroxypropan-2-yl)cyclohexyl)quinoline-3-carboxamide 7-(difluoromethoxy)-N-[(1r,4r)-4-(2-hydroxypropan-2-yl)cyclohexyl]quinoline-3-carboxamide HPGDS inhibitor 2, 10 mM in DMSO 2101626-26-8