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STAD 2

STAD 2 structure

CAS No.: 1542100-77-5

Chemical Name:: STAD 2

Synonyms: STAD 2;L-Lysinamide, L-alanyl-L-leucyl-L-lysyl-N11-[N2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]acetyl]-L-lysyl-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-phenylalanyl-L-leucyl-L-valyl-L-seryl]-(2S,11S)-2,11-diamino-11-carboxy-2-methyl-6-dodecenoyl-L-alanyl-L-leucyl-, (4→1)-lactam

CBNumber:: CB44902876

Molecular Formula:: C102H182N24O22

Molecular Weight:: 2096.72

MDL Number:

MOL File:: 1542100-77-5.mol

Last updated:2025-04-18 09:52:20

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STAD 2 Properties

Boiling point	1997.4±65.0 °C(Predicted)
Density	1.22±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Soluble to 1 mg/ml in 50% acetonitrile / water
pka	12.55±0.70(Predicted)
form	Solid
color	White to off-white

STAD 2 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	6566	STAD2	1542100-77-5	500U	$489	2021-12-16	Buy

Product number	Packaging	Price	Buy
6566	500U	$489	Buy

STAD 2 Chemical Properties,Uses,Production

Uses

STAD 2 is a potent and selective disruptor of PKA-RII, with a Kd of 6.2 nM. STAD 2 disrupts interactions between PKA and AKAP in an isoform-selective manner. STAD 2 displays antimalarial activity through a PKA-independent mechanism[1][2].

References

[1] Wang Y, et, al. Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides. ACS Chem Biol. 2014 Mar 21;9(3):635-42. DOI:10.1021/cb400900r
[2] Flaherty BR, et, al. The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism. PLoS One. 2015 May 26;10(5):e0129239. DOI:10.1371/journal.pone.0129239

STAD 2 Preparation Products And Raw materials

Raw materials

Preparation Products

STAD 2 Suppliers

Global( 15)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.		support@targetmol.com	United States	38663	58
Changsha MOL Changes Biotechnology Co., Ltd.	+8619375158599	info@molchanges.com	China	5221	58
BOC Sciences	16314854226	info@bocsci.com	United States	9923	65
Chengdu Youngshe Chemical Co., Ltd.	+86-17380623303 +86-17380623303	Caroline@youngshechem.com	China	4804	58
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919	Eric@peptidego.com	China	7061	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Hangzhou Go Top Peptide Biotech	15397062932	sales1@gotopbio.com	China	2884	58
Shaoxing Junyu Biotechnology Co., LTD	0571-88211921 19105816207	sales4@gotopbio.com	China	5147	58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD	0571-87213919 17306812703	3007955328@qq.com	China	6628	58
Shanghai HongTide Biotechnology Co.,Ltd.	19961912513	sales@hongtide.com	China	4604	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Changsha MOL Changes Biotechnology Co., Ltd.	58
BOC Sciences	65
Chengdu Youngshe Chemical Co., Ltd.	58
Hangzhou Peptidego Biotech Co.,Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
Hangzhou Go Top Peptide Biotech	58
Shaoxing Junyu Biotechnology Co., LTD	58
Hangzhou Sinoda Pharmaceutical Technology Co. LTD	58
Shanghai HongTide Biotechnology Co.,Ltd.	58

STAD 2 L-Lysinamide, L-alanyl-L-leucyl-L-lysyl-N11-[N2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]acetyl]-L-lysyl-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-phenylalanyl-L-leucyl-L-valyl-L-seryl]-(2S,11S)-2,11-diamino-11-carboxy-2-methyl-6-dodecenoyl-L-alanyl-L-leucyl-, (4→1)-lactam 1542100-77-5