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METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 structure

CAS No.: 50593-91-4

Chemical Name:: METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97

Synonyms: methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate;fanyL;)-4- pyrimidinecarboxyL;Methyl 5-BroMo-2-(Methylthio)-4-pyriMidinecarboxylate;Methyl 5-bromo-2-(methylsulfanyl)-4-pyrimidinecarboxylate;methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate;Methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate ,97%;THYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97;METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97;4-PyriMidinecarboxylic acid, 5-broMo-2-(Methylthio)-, Methyl ester

CBNumber:: CB4506636

Molecular Formula:: C7H7BrN2O2S

Molecular Weight:: 263.11

MDL Number:: MFCD05664428

MOL File:: 50593-91-4.mol

MSDS File:: SDS

Last updated:2026-05-28 05:04:12

Product description	Number	Pack Size	Price
Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	M12200	10g	$27
Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	M12200	25g	$50
Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	M12200	50g	$100
Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	M12200	100g	$180
Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	M12200	250g	$540
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METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 Properties

Melting point	67 °C
Boiling point	348.7±22.0 °C(Predicted)
Density	1.69±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	-2.91±0.29(Predicted)
form	Solid
color	Pale yellow
Water Solubility	Slightly soluble in water (0.42 g/L).
InChI	InChI=1S/C7H7BrN2O2S/c1-12-6(11)5-4(8)3-9-7(10-5)13-2/h3H,1-2H3
InChIKey	MYZJIEWTRJTWCD-UHFFFAOYSA-N
SMILES	C1(SC)=NC=C(Br)C(C(OC)=O)=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H312-H315-H319-H332-H335

Precautionary statements

P261-P280-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Risk Statements

43-36/37/38-20/21/22

Safety Statements

36/37-36/37/39-26-22

RIDADR

UN2811

HazardClass

6.1

HazardClass

IRRITANT

HS Code

29335990

NFPA 704

	1
2		0

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 price More Price(44)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Synthonix	M12200	Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	50593-91-4	10g	$27	2026-05-06	Buy
Synthonix	M12200	Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	50593-91-4	25g	$50	2026-05-06	Buy
Synthonix	M12200	Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	50593-91-4	50g	$100	2026-05-06	Buy
Synthonix	M12200	Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	50593-91-4	100g	$180	2026-05-06	Buy
Synthonix	M12200	Methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate 95+%	50593-91-4	250g	$540	2026-05-06	Buy

Product number	Packaging	Price	Buy
M12200	10g	$27	Buy
M12200	25g	$50	Buy
M12200	50g	$100	Buy
M12200	100g	$180	Buy
M12200	250g	$540	Buy

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 Chemical Properties,Uses,Production

Chemical Properties

Yellow solid

Uses

It can be used as pharmaceutical raw material and intermediate.

Synthesis

67-56-1

5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid

50593-92-5

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97

50593-91-4

General procedure for the preparation of methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate: 5-bromo-2-(methylthio)pyrimidine-4-carboxylic acid (7.64 g, 30.7 mmol) was dissolved in methanol (60 mL). Sulfuric acid (2 mL) was added to the solution and the mixture was subsequently heated to reflux for 24 hours. Upon completion of the reaction, the mixture was poured into ice water and extracted with dichloromethane (DCM). The organic phase was washed with saturated aqueous sodium bicarbonate solution, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target compound methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate (6.42 g, 80% yield). The product was characterized by 1H NMR (500 MHz, CDCl3): δ 8.72 (s, 1H), 4.01 (s, 3H), 2.58 (s, 3H).LCMS (ESI) analysis showed a retention time of Rt = 2.35 min and a molecular ion peak 263 [M + H]+.

References

[1] Patent: WO2014/37750, 2014, A1. Location in patent: Paragraph 00149; 0046-0050
[2] Patent: WO2015/128676, 2015, A1. Location in patent: Page/Page column 117-118
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 6, p. 2215 - 2226
[4] Patent: WO2017/221100, 2017, A1. Location in patent: Paragraph 00284
[5] Patent: EP3305785, 2018, A1. Location in patent: Paragraph 0167; 0168

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Clindamycin palmitate hydrochloride Sodium chloride Triethylamine 2-Methyl-2-thiopseudourea sulfate

Methanol Mucobromic acid Sulfuric acid 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid

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Preparation Products

Methyl 5-bromo-2-(methylamino)pyrimidine-4-carboxylate 2-(methylthio)pyrido[3,4-d]pyrimidin-8(7H)-one

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 Suppliers

Global( 100)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29792	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	20582	58
Shanghai Scochem Technology Co., Ltd	+86-021-33758897 +86-13701882790	sales@scochem.com	China	1977	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58

Supplier	Advantage
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58
Shanghai Scochem Technology Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 50593-91-4	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2020-01-10	METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 50593-91-4	$6.68	1KG	97%-99%	1kg-1000kg	Career Henan Chemical Co

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97
50593-91-4
$1.10
99.00%
Dideu Industries Group Limited

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE,
50593-91-4
$6.68
97%-99%
Career Henan Chemical Co

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 Spectrum

METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97(50593-91-4)¹HNMR

50593-91-4(METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97)Related Search:

PYRIMIDINE-4-CARBOXYLIC ACID METHYL ESTER 5-Bromopyrimidine 5-BROMO-4-PYRIMIDINECARBOXALDEHYDE 5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid 2-METHYLSULFANYL-PYRIMIDINE-4-CARBALDEHYDE

5-BROMO-2-(METHYLTHIO)PYRIMIDINE 2-Thiomethylpyrimidine-4-carboxylic acid METHYL 5-BROMO-4-PYRIMIDINECARBOXYLATE METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 5-BROMO-4-PYRIMIDINECARBOXYLIC ACID

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5-Bromo-2-(methylsulfanyl)pyrimidine-4-carboxylic acid methyl ester methyl 5-bromo-2-(methylsulfanyl)pyrimidine-4-carboxylate Methyl 5-bromo-2-(methylsulfanyl)-4-pyrimidinecarboxylate METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 Methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate ,97% Methyl 5-BroMo-2-(Methylthio)-4-pyriMidinecarboxylate THYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 4-PyriMidinecarboxylic acid, 5-broMo-2-(Methylthio)-, Methyl ester )-4- pyrimidinecarboxyL fanyL METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 ISO 9001：2015 REACH methyl 5-bromo-2-(methylthio)pyrimidine-4-carboxylate 50593-91-4 C7H7BrN2O2S Heterocycle-Pyrimidine series