1,4-dihydroxy-2naphthoic acid methyl ester
- CAS No.
- 77060-74-3
- Chemical Name:
- 1,4-dihydroxy-2naphthoic acid methyl ester
- Synonyms
- Methyl 1,4-dihydroxy-2-phthoate;METHYL-1,4-DIHYDROXY-2-NAPHTHOATE;1,4-Dihydroxy-2-naphthoic acid methylester;1,4-Dihydroxy-2-naphthalenecarboxylic acid methyl ester;2-Naphthalenecarboxylic acid, 1,4-dihydroxy-, methyl ester
- CBNumber:
- CB4511614
- Molecular Formula:
- C12H10O4
- Molecular Weight:
- 218.21
- MDL Number:
- MFCD00573066
- MOL File:
- 77060-74-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H335-H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
1,4-dihydroxy-2naphthoic acid methyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Ambeed | A704843 | Methyl 1,4-dihydroxy-2-naphthoate 99% | 77060-74-3 | 1g | $14 | 2026-06-05 | Buy |
| Ambeed | A704843 | Methyl 1,4-dihydroxy-2-naphthoate 99% | 77060-74-3 | 5g | $40 | 2026-06-05 | Buy |
| Ambeed | A704843 | Methyl 1,4-dihydroxy-2-naphthoate 99% | 77060-74-3 | 25g | $157 | 2026-06-05 | Buy |
| Ambeed | A704843 | Methyl 1,4-dihydroxy-2-naphthoate 99% | 77060-74-3 | 100g | $584 | 2026-06-05 | Buy |
| aablocks | AA005ED5 | Methyl 1,4-Dihydroxy-2-Naphthoate 99% | 77060-74-3 | 1g | $13 | 2026-05-28 | Buy |
1,4-dihydroxy-2naphthoic acid methyl ester Chemical Properties, Uses, Production
Uses
1,4-dihydroxy-2naphthoic acid methyl ester can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
To a stirred solution of LiOt-Bu (3.20 mmol) in THF (10 mL) at -78 C(CHCl3-liq N2 bath) under an inert atmosphere was added a solutionof isocyanophthalide (1.0 mmol) in THF (5 mL). The resulting yellowish solution was stirred at -78 C for 25 min, after which a solution of a Michael acceptor (1.0-1.5 equiv unless otherwise stated) in THF (5mL) was added. The cooling bath was removed after ca. 1 h at -78 C and the mixture was brought to r.t. over a period of 1 h and stirred fora further 2-6 h. The reaction was then quenched with 10% aq NH4Cl(15 mL) and the resulting solution was concentrated. The residue was diluted with EtOAc (50 mL) and the layers were separated. The aqueous layer was extracted with EtOAc (3 á 25 mL). The combined extracts were washed with H2O (15 mL) and brine (15 mL), dried (anhydNa2SO4), and concentrated under reduced pressure. The crude product was purified by column chromatography (silica gel) or by recrystallizationto obtain the pure product.
1,4-dihydroxy-2naphthoic acid methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451683 15021268886 | sales@arborchemical.com | China | 837 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hunan HuaTeng Pharmaceutical Co., Ltd., | 400-8592883 15367835770 | sales@huatengsci.com | China | 5869 | 58 |
| Shanghai QianJin Chemical Technology Co., Ltd | 021-20900665 17321230821 | 2986274987@qq.com | China | 754 | 55 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| Nanjing Duolong Bio-tech Co.,Ltd. | 18905173768 | 52513593@qq.com | China | 2337 | 50 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
View Latest Price from 1,4-dihydroxy-2naphthoic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | Methyl 1,4-dihydroxy-2-naphthoate
77060-74-3
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-02-26 | Methyl 1,4-dihydroxy-2- naphthoate
77060-74-3
|
1KG | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-01-09 | Methyl 1,4-dihydroxy-2-naphthoate
77060-74-3
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- Methyl 1,4-dihydroxy-2-naphthoate
77060-74-3
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Methyl 1,4-dihydroxy-2- naphthoate
77060-74-3
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
-
- Methyl 1,4-dihydroxy-2-naphthoate
77060-74-3
- $9.80
- ≥99%
- Career Henan Chemical Co
