REG4 antibody
- CAS No.
- Chemical Name:
- REG4 antibody
- Synonyms
- REG4 antibody
- CBNumber:
- CB45691753
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
REG4 antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb255753 | REG4 Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb158274 | REG4 antibody Affinity purified by Protein A | 100μg | $421.6 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb158274 | REG4 antibody Affinity purified by Protein A | 200μg | $673.2 | 2021-12-16 | Buy |
REG4 antibody Chemical Properties, Uses, Production
Source
Rabbit
Reactivity
Human
Background
Reg4 is a member of a multigene family of Reg proteins. Reg proteins are secreted glycoproteins belonging to the calcium dependent lectin superfamily, although they can in fact bind polysaccharides, mannan, and heparin in the absence of calcium.Reg4 is expressed in the gastrointestinal tract, in normal colon mucosa, and is upregulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease.It has recently been shown that Reg4 marks a population of deep secretory cells at the bottom of the crypts in the colon. In the upper gastrointestinal tract, Paneth cells support the Lgr5+ positive stem cells that reside at the base of deep crypts by providing signals such as Wnt3, EGF, and Notch ligands for stem cell maintenance. No Paneth cells, however, exist in the colon crypts. It is proposed that the Reg4+ population serves as an analogous support system for the LGR5+ positive stem cell population in the colon.
References
[1] Hartupee, J.C. et al. (2001) Biochim Biophys Acta 1518, 287-93.
[2] Kämäräinen, M. et al. (2003) Am J Pathol 163, 11-20.
[3] Ho, M.R. et al. (2010) J Mol Biol 402, 682-95.
[4] Violette, S. et al. (2003) Int J Cancer 103, 185-93.
[5] Zhang, Y.W. et al. (2003) World J Gastroenterol 9, 2635-41.
[6] Sasaki, N. et al. (2016) Proc Natl Acad Sci U S A 113, E5399-407.
REG4 antibody Preparation Products And Raw materials
Raw materials
Preparation Products
REG4 antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
