ChemicalBook >> CAS DataBase List >>1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
- CAS No.
- 292606-35-0
- Chemical Name:
- 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
- Synonyms
- N-Boc-2,2-dimethyl-1,3-propanediamine;N-Boc-2,2-dimethyl-1,3-diaminopropane;BOC-1-AMINO-2,2-DIMETHYL-1,3-PROPYLDIAMINE;1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE;tert-Butyl (3-Amino-2,2-dimethylpropyl)carbamate;tert-Butyl N-(3-amino-2,2-dimethylpropyl)carbamate;(S)-(+)-5-1-Boc-amino-2,2-dimethyl-1,3-propanediamine;N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine;(3-Amino-2,2-dimethylpropyl)carbamic Acid tert-Butyl Ester;N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine >
- CBNumber:
- CB4666820
- Molecular Formula:
- C10H22N2O2
- Molecular Weight:
- 202.29
- MDL Number:
- MFCD01076212
- MOL File:
- 292606-35-0.mol
Last updated:2025-07-24 18:13:47
| Product description | Number | Pack Size | Price |
| N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine >98.0%(GC)(T) | B3052 | 1g | $51 |
| N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine >98.0%(GC)(T) | B3052 | 5g | $248 |
| tert-Butyl(3-Amino-2,2-dimethylpropyl)carbamate | B789250 | 100mg | $60 |
| 1-Boc-amino-2,2-dimethyl-1,3-propanediamine | FB149670 | 250mg | $85 |
| 1-Boc-amino-2,2-dimethyl-1,3-propanediamine | FB149670 | 1g | $259 |
| Melting point | 74 °C |
|---|---|
| Boiling point | 293.8±23.0 °C(Predicted) |
| Density | 0.964±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C, protect from light |
| form | powder to crystal |
| pka | 12.86±0.46(Predicted) |
| color | White to Almost white |
| CAS DataBase Reference | 292606-35-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| HS Code | 2924.19.8000 | |||||||||
| NFPA 704 |
|
1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B3052 | N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine >98.0%(GC)(T) | 292606-35-0 | 1g | $51 | 2025-07-31 | Buy |
| TCI Chemical | B3052 | N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine >98.0%(GC)(T) | 292606-35-0 | 5g | $248 | 2025-07-31 | Buy |
| TRC | B789250 | tert-Butyl(3-Amino-2,2-dimethylpropyl)carbamate | 292606-35-0 | 100mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB149670 | 1-Boc-amino-2,2-dimethyl-1,3-propanediamine | 292606-35-0 | 250mg | $85 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB149670 | 1-Boc-amino-2,2-dimethyl-1,3-propanediamine | 292606-35-0 | 1g | $259 | 2021-12-16 | Buy |
1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Chemical Properties,Uses,Production
Synthesis
7328-91-8
24424-99-5
292606-35-0
Di-tert-butyl dicarbonate was slowly added to a solution of 2,2-dimethylpropane-1,3-diamine in dichloromethane (DCM) (500 mL) of 2,2-dimethylpropane-1,3-diamine (80 g, 783 mmol) and di-tert-butyl dicarbonate (91 mL, 391 mmol) at 0 °C. The reaction mixture was stirred at ambient temperature for 12 hours. Subsequently, the reaction mixture was concentrated to remove the solvent. The crude product was purified by column chromatography (neutral alumina) using methanol: dichloromethane (1:9) as eluent to afford tert-butyl (3-amino-2,2-dimethylpropyl)carbamate (50 g, 247 mmol, 31.6% yield) as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 0.85 (s, 6H), 1.44 (s, 9H), 2.35-2.52 (m, 2H), 3.00 (br d, J = 6.14Hz, 2H), 5.16 (br s, 1H).
References
[1] Patent: WO2018/109648, 2018, A1. Location in patent: Page/Page column 64
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 2, p. 236 - 246
[3] Patent: US2005/20623, 2005, A1. Location in patent: Page 116
[4] Patent: EP1550657, 2005, A1. Location in patent: Page/Page column 46
Synthesis of 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE from 2,2-DIMETHYL-1,3-PROPANEDIAMINE and Di-tert-butyl dicarbonate
1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Preparation Products And Raw materials
1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Suppliers
Global( 96)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Kindchem(Nanjing)Co.,Ltd | +86-025-025-85281586 +8618651653755 | sales@kindchem.cn | China | 1226 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49973 | 58 |
View Lastest Price from 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-08 | tert-Butyl (3-amino-2,2-dimethylpropyl)carbamate
292606-35-0
|
US $1.00 / g | 1g | Min98% HPLC | g/kg/ton | Career Henan Chemical Co |
-
- tert-Butyl (3-amino-2,2-dimethylpropyl)carbamate
292606-35-0
- US $1.00 / g
- Min98% HPLC
- Career Henan Chemical Co
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292606-35-0
AMIDE
Monoprotected Diaminoalkanes
N-Boc-diaminoalkanes
N-BOC
pharmacetical
