SERUM SPREADING FACTOR
- CAS No.
- 83380-82-9
- Chemical Name:
- SERUM SPREADING FACTOR
- Synonyms
- VITRONECTIN;V75;VTN;VNT;Vitronectins;S-PROTEIN, HUMAN;S-PROTEIN, BOVINE;HUMAN VITRONECTIN;VITRONECTIN, HUMAN;VITRONECTIN, MOUSE
- CBNumber:
- CB4674713
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD06200193
- MOL File:
- Mol file
- MSDS File:
- SDS
| storage temp. | 2-8°C |
|---|---|
| solubility | water: soluble 0.050 mg/mL, clear, colorless |
| form | lyophilized powder |
| color | White to off-white |
| biological source | human plasma |
| Water Solubility | water: soluble 0.050mg/mL, clear, colorless |
| FDA UNII | C4492BL5NJ |
| UNSPSC Code | 12352202 |
| NACRES | NA.75 |
SAFETY
Risk and Safety Statements
| Hazard Codes | B |
|---|---|
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
SERUM SPREADING FACTOR price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | V9881 | Vitronectin from bovine plasma lyophilized powder, BioReagent, suitable for cell culture | 83380-82-9 | 50μg | $494 | 2026-04-30 | Buy |
| Sigma-Aldrich | V8379 | Vitronectin from human plasma lyophilizedpowder,BioReagent,suitableforcellculture | 83380-82-9 | 50μg | $494 | 2026-04-30 | Buy |
| Sigma-Aldrich | V0132 | Vitronectin from rat plasma lyophilized powder, BioReagent, suitable for cell culture | 83380-82-9 | 50μg | $511 | 2026-04-30 | Buy |
| Sigma-Aldrich | SRP3186 | Vitronectin human recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture | 83380-82-9 | 250 μg | $418 | 2026-04-30 | Buy |
| Sigma-Aldrich | 5051 | Vitronectin from human plasma, suitable for cell culture, solution | 83380-82-9 | 0.1MG | $235 | 2026-04-30 | Buy |
SERUM SPREADING FACTOR Chemical Properties, Uses, Production
Uses
Vitronectin can be used with cells with integrin receptors that bind vitronectin, including platelets, endothelial cells, melanoma cells, and osteosarcoma. It is recommended as a cell culture substratum at 0.1 μg/cm2. Optimal conditions for attachment depend on cell line and application.
Uses
Vitronectin human has been used to study the effects of ECM (extracellular matrix) ligands on C6 astroglioma cells. It has also been used as an attachment-promoting protein for coating the cell plates.
Uses
Vitronectin has been used as a constituent of serum free media for culturing skeletal muscle and for growth and myelination of motoneurons by Schwann cells. It has also been used as a constituent of enriched co-culture media for culturing rat spinal cord.
General Description
Vitronectin is a secreted glycoprotein which is synthesized in the liver. It is also secreted by respiratory epithelial cells and is present in healthy lungs. It circulates primarily in monomeric form, but can undergo conformational change to a structure that forms disulfide linked multimers. Recombinant human Vitronectin is a 459 amino acid single chain monomeric protein, which migrates at an apparent molecular weight of 75kDa by SDS-PAGE under reducing conditions. Recombinant vitronectin can function as a chemically defined matrix component in human embryonic stem cell renewal media.
Biochem/physiol Actions
The multimeric Vitronectin can efficiently bind to and incorporate into the extracellular matrix. Within the matrix, Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Its interaction with integrin αvβ3 enhances hypoxia resistance and tumor cell invasion. It is also associated with cancer progression in various cancers. Vitronectin is involved in wound repair and also controls complement system. It works as a marker of profibrotic activity in liver, heart and kidney.
SERUM SPREADING FACTOR Preparation Products And Raw materials
Raw materials
Preparation Products
SERUM SPREADING FACTOR Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821; | sales@klbio.cn | China | 9619 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Abmole Bioscience Inc. | 19821158099 | sales@abmole.cn | China | 4485 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| ACROBiosystems | 13121935750 | jiaxin.zhao@acrobiosystems.com | China | 1582 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 10763 | 58 |
