4-Amino-3-nitrobenzonitrile
- CAS No.
- 6393-40-4
- Chemical Name:
- 4-Amino-3-nitrobenzonitrile
- Synonyms
- BUTTPARK 96\04-65;4-Cyano-2-nitroaniline;2-Nitro-4-cyanoaniline;3-Nitro-4-Aminobenzonitrile;4-AMINO-3-NITROBENZONITRILE;Benzonitrile, 4-amino-3-nitro-;4-Amino-3-nitrobenzonitrile >4-Amino-3-nitrobenzonitrile,98%;4-AMINO-3-NITROBENZONITRILE 98%;4-AMino-3-nitrobenzonitrile, 97+%
- CBNumber:
- CB4675356
- Molecular Formula:
- C7H5N3O2
- Molecular Weight:
- 163.13
- MDL Number:
- MFCD00013373
- MOL File:
- 6393-40-4.mol
- MSDS File:
- SDS
| Melting point | 159-162 °C (lit.) |
|---|---|
| Boiling point | 349.8±32.0 °C(Predicted) |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in ethanol and benzene. |
| pka | -3.52±0.10(Predicted) |
| form | Powder, Crystals or Crystalline Powder |
| color | Yellow |
| BRN | 778939 |
| InChI | InChI=1S/C7H5N3O2/c8-4-5-1-2-6(9)7(3-5)10(11)12/h1-3H,9H2 |
| InChIKey | JAHADAZIDZMHOP-UHFFFAOYSA-N |
| SMILES | C(#N)C1=CC=C(N)C([N+]([O-])=O)=C1 |
| CAS DataBase Reference | 6393-40-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-36/37/39 | |||||||||
| RIDADR | 3276 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| NFPA 704 |
|
4-Amino-3-nitrobenzonitrile price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 324698 | 4-Amino-3-nitrobenzonitrile 98% | 6393-40-4 | 5g | $61.6 | 2023-06-20 | Buy |
| TCI Chemical | A2447 | 4-Amino-3-nitrobenzonitrile >98.0%(GC) | 6393-40-4 | 5g | $170 | 2025-07-31 | Buy |
| TCI Chemical | A2447 | 4-Amino-3-nitrobenzonitrile >98.0%(GC) | 6393-40-4 | 25g | $678 | 2025-07-31 | Buy |
| TRC | A618398 | 4-Amino-3-nitrobenzonitrile | 6393-40-4 | 1g | $55 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK156087 | 4-Amino-3-nitrobenzonitrile 98% | 6393-40-4 | 5g | $127 | 2021-12-16 | Buy |
4-Amino-3-nitrobenzonitrile Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
4-Amino-3-nitrobenzonitrile is used in gamma irradiations effect on release of this compound from polyanhydride matrixes.
Uses
Gamma irradiations effect on release of 4-amino-3-nitrobenzonitrile from polyanhydride matrixes.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 36, p. 1746, 1993 DOI: 10.1021/jm00064a008
Synthesis
35704-19-9
6393-40-4
General procedure for the synthesis of 4-amino-3-nitrobenzonitrile from 4'-cyanoacetanilide: potassium nitrate (15.6 mmol) was dissolved in 8 mL of concentrated sulfuric acid and the mixture was cooled to below 0 °C. Under this cooling condition, 7.8 mmol of 4'-cyanoacetanilide was slowly added, keeping the reaction temperature at 0 °C for 3.5 hours. Upon completion of the reaction, the mixture was poured into an ice water bath and the resulting yellow solid was collected by filtration and washed with a small amount of cold water. Subsequently, the resulting product was suspended in 30 mL of 2 mol/L sulfuric acid solution and heated under reflux conditions for 3 hours. At the end of the reaction, the suspension was cooled to room temperature, and the yellow solid was again collected by filtration and washed with a small amount of cold water to finally obtain the target product 4-amino-3-nitrobenzonitrile in 74% yield.
References
[1] Journal of the Brazilian Chemical Society, 2018, vol. 29, # 6, p. 1304 - 1317
[2] Journal of the Chemical Society, 1950, p. 1722,1725
[3] Journal of Medicinal Chemistry, 1995, vol. 38, # 10, p. 1786 - 1792
[4] Australian Journal of Chemistry, 1994, vol. 47, # 2, p. 247 - 262
[5] Journal of Medicinal Chemistry, 1993, vol. 36, # 12, p. 1746 - 1753
4-Amino-3-nitrobenzonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20195 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29733 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12875 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 4-Amino-3-nitrobenzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-12-26 | 4-Amino-3-nitrobenzonitrile
6393-40-4
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2021-07-13 | 4-Amino-3-nitrobenzonitrile
6393-40-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-10 | 4-Amino-3-nitrobenzonitrile
6393-40-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 4-Amino-3-nitrobenzonitrile
6393-40-4
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-Amino-3-nitrobenzonitrile
6393-40-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 4-Amino-3-nitrobenzonitrile
6393-40-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
