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3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE structure

CAS No.: 83507-33-9

Chemical Name:: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE

Synonyms: (1R,5S)-3-benzyl-3-azabicyclo[3.2.1]octan-8-one;3-Benzyl-3-azabicyclo[3.2...;4-(Boc-ami)-3,6-dichloropyridazine;3-Benzyl-3-azabicylo[3.2.1]octan-8-one;3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE;3-(phenylmethyl)-3-Azabicyclo[3.2.1]octan-8-one;3-Azabicyclo[3.2.1]octan-8-one, 3-(phenylMethyl)-

CBNumber:: CB4681553

Molecular Formula:: C14H17NO

Molecular Weight:: 215.29

MDL Number:: MFCD08275096

MOL File:: 83507-33-9.mol

MSDS File:: SDS

Last updated:2025-08-05 18:30:54

Product description	Number	Pack Size	Price
3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 97.0%	4H56-1-827	250mg	$190
3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 97.0%	4H56-1-827	1g	$490
3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 97.0%	122235	1g	$528
3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 95+%	CD11049083	25g	$545
3-benzyl-3-azabicyclo[3.2.1]octan-8-one 95+%	CM101031	25g	$550
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3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Properties

Boiling point	342.9±22.0 °C(Predicted)
Density	1.140±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	7.08±0.20(Predicted)
Appearance	Off-white to yellow Solid
InChI	InChI=1S/C14H17NO/c16-14-12-6-7-13(14)10-15(9-12)8-11-4-2-1-3-5-11/h1-5,12-13H,6-10H2
InChIKey	DCDAOVIVXGHHHU-UHFFFAOYSA-N
SMILES	C12C(=O)C(CC1)CN(CC1=CC=CC=C1)C2

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
SynQuest Laboratories	4H56-1-827	3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 97.0%	83507-33-9	250mg	$190	2021-12-16	Buy
SynQuest Laboratories	4H56-1-827	3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 97.0%	83507-33-9	1g	$490	2021-12-16	Buy
Matrix Scientific	122235	3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 97.0%	83507-33-9	1g	$528	2021-12-16	Buy
Crysdot	CD11049083	3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 95+%	83507-33-9	25g	$545	2021-12-16	Buy
Chemenu	CM101031	3-benzyl-3-azabicyclo[3.2.1]octan-8-one 95+%	83507-33-9	25g	$550	2021-12-16	Buy

Product number	Packaging	Price	Buy
4H56-1-827	250mg	$190	Buy
4H56-1-827	1g	$490	Buy
122235	1g	$528	Buy
CD11049083	25g	$545	Buy
CM101031	25g	$550	Buy

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Chemical Properties,Uses,Production

Synthesis

50-00-0

120-92-3

100-46-9

83507-33-9

General procedure for the synthesis of 3-benzyl-3-azabicyclo[3.2.1]octan-8-one (Intermediate I-32) from formaldehyde, cyclopentanone, and benzylamine: In a 2L round-bottomed flask equipped with a condenser tube and nitrogen introduction tube, benzylamine (127 g, 1.2 mol, 1.0 equiv.) and methanol (800 mL) were added, followed by the slow dropwise addition of glacial acetic acid (127 g, 1.2 mol, 1.0 equiv). Intermediate I-31 (100 g, 1.2 mol, 1.0 eq.) and paraformaldehyde (107 g, 3.6 mol, 3.0 eq.) were then added. The reaction mixture was stirred at 80 °C for 3 hours and then continued at room temperature for 18 hours. Upon completion of the reaction, the excess solvent was removed by evaporation and the residue was diluted with ethyl acetate and solid sodium bisulfite (104 g) was added. The crude reaction mixture was continued to be stirred for 1.5 hours and subsequently extracted with ethyl acetate. The organic layers were combined, dried with anhydrous Na2SO4, filtered to remove solids and the filtrate was concentrated by evaporation. The crude product was purified by silica gel column chromatography to afford intermediate I-32 (47.2 g, 18% yield) as a yellow oil.1H-NMR (400 MHz, CDCl3) δ: 7.35 (m, 4H), 7.26 (m, 1H), 3.59 (s, 2H), 2.93 (m, 2H), 2.39 (d, J=10.8 Hz, 2H). 2.50 (m, 2H), 1.93 (m, 2H), 1.81 (m, 2H).MS (ESI): m/z 216.1 (M+H+).

References

[1] Patent: US2011/65694, 2011, A1. Location in patent: Page/Page column 64
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 18, p. 2831 - 2840
[3] Patent: US2009/12116, 2009, A1. Location in patent: Page/Page column 18

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Preparation Products And Raw materials

Raw materials

3- Benzyl -3-spiro[bicyclo[3.2.1]cyclooctane-8,2'-[1,3]Dioxane] Formaldehyde Cyclopentanone Benzylamine Acetic acid

Methanol

1of2

Preparation Products

tert-butyl 8-oxo-3-azabicyclo[3.2.1]octane-3-carboxylate

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Suppliers

Global( 164)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16513	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29795	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Antai Fine Chemical Technology Co.,Limited	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
SIMAGCHEM CORP	58

View Lastest Price from 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-17	3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 83507-33-9	US $2.00-6.00 / kg	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-12-01	3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE 83507-33-9	US $0.00 / kg	1kg	98%	1000kg	Shaanxi Dideu New Materials Co. Ltd
2021-07-02	3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE 83507-33-9	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

3-Benzyl-3-azabicyclo[3.2.1]octan-8-one
83507-33-9
US $2.00-6.00 / kg
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE
83507-33-9
US $0.00 / kg
98%
Shaanxi Dideu New Materials Co. Ltd

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE
83507-33-9
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Spectrum

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE(83507-33-9)¹HNMR

83507-33-9(3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE)Related Search:

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3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE 3-Benzyl-3-azabicylo[3.2.1]octan-8-one 3-Azabicyclo[3.2.1]octan-8-one, 3-(phenylMethyl)- 3-Benzyl-3-azabicyclo[3.2... (1R,5S)-3-benzyl-3-azabicyclo[3.2.1]octan-8-one 3-(phenylmethyl)-3-Azabicyclo[3.2.1]octan-8-one 4-(Boc-ami)-3,6-dichloropyridazine 83507-33-9 8350-33-9 835-07-3 CHIRAL CHEMICALS Novel building