6-Chloro-2-tetralone
- CAS No.
- 17556-18-2
- Chemical Name:
- 6-Chloro-2-tetralone
- Synonyms
- 6-Chloro-3,4-dihydronaphthalen-2(1H)-one;6-chloro-1,2,3,4-tetrahydronaphthalen-2-one;6-CHLORO-2-TETRALONE;6-Chlorotetralin-2-one;6-CHLORO-3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE;6-Chloro-3,4-dihydro-2(1H)-naphthalenone;2(1H)-Naphthalenone, 6-chloro-3,4-dihydro-
- CBNumber:
- CB4714158
- Molecular Formula:
- C10H9ClO
- Molecular Weight:
- 180.63
- MDL Number:
- MFCD03788443
- MOL File:
- 17556-18-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 60-65 °C(lit.) |
|---|---|
| Boiling point | 115 °C(Press: 0.01 Torr) |
| Density | 1.248±0.06 g/cm3(Predicted) |
| storage temp. | -20°C, protect from light, stored under nitrogen |
| Appearance | Light yellow to yellow Solid |
| CAS DataBase Reference | 17556-18-2(CAS DataBase Reference) |
6-Chloro-2-tetralone price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR12932 | 6-Chloro-3,4-dihydronaphthalen-2(1H)-one 98% | 17556-18-2 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR12932 | 6-Chloro-3,4-dihydronaphthalen-2(1H)-one 98% | 17556-18-2 | 250mg | $30 | 2026-06-04 | Buy |
| Apolloscientific | OR12932 | 6-Chloro-3,4-dihydronaphthalen-2(1H)-one 98% | 17556-18-2 | 1g | $79 | 2026-06-04 | Buy |
| Apolloscientific | OR12932 | 6-Chloro-3,4-dihydronaphthalen-2(1H)-one 98% | 17556-18-2 | 5g | $300 | 2026-06-04 | Buy |
| Apolloscientific | OR12932 | 6-Chloro-3,4-dihydronaphthalen-2(1H)-one 98% | 17556-18-2 | 25g | $1465 | 2026-06-04 | Buy |
6-Chloro-2-tetralone Chemical Properties, Uses, Production
Synthesis
Under nitrogen protection, anhydrous dichloromethane (350 mL) and aluminum trichloride (26.6 g, 200.00 mmol) were added sequentially to a 500 mL three-necked flask. The system was a suspension. The mixture was stirred and cooled to -78 °C. A solution of 2-(4-chlorophenyl)acetyl chloride (18.9 g, 100 mmol) in dichloromethane (50 mL) was slowly added dropwise over a period of 1 hour. After the addition was complete, ethylene gas was vigorously bubbled into the solution for 10 minutes to gradually raise the reaction mixture to room temperature and stir at that temperature for 3.5 hours. The reaction progress was monitored by TLC. After confirming the completion of the reaction, the reaction solution was cooled to 0 °C and quenched with 100 mL of water. The mixture was allowed to stand and separated. The organic layer was washed sequentially with 2 M hydrochloric acid and saturated sodium bicarbonate aqueous solution, dried with anhydrous magnesium sulfate, filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (petroleum ether: ethyl acetate 20:1) to give 11.2 g of yellow solid product (yield 62%).
Uses
6-Chloro-3,4-dihydro-1H-2-naphthone, as a halogenated aromatic heterocyclic compound, has good chemical activity due to the presence of halogen and carbonyl functional groups, which allows it to react well with other compounds, such as substitution reactions and affinity addition reactions. Therefore, 6-chloro-3,4-dihydro-1H-2-naphthone is a very important pharmaceutical intermediate.
6-Chloro-2-tetralone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 94607 | 76 |
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai AmasPharm Co., Ltd. | 021-54540637 18621091017 | sales@amaspharm.com | China | 787 | 62 |
| ZhengZhou HuaWen Chemical Co.Ltd | 0370-2785118 17550508557 | 675141927@qq.com | China | 3201 | 55 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
View Latest Price from 6-Chloro-2-tetralone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | 6-Chloro-3,4-dihydro-2(1H)-naphthalenone
17556-18-2
|
$2.20-8.80 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2020-01-09 | 6-Chloro-2-tetralone
17556-18-2
|
$6.68 | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 6-Chloro-3,4-dihydro-2(1H)-naphthalenone
17556-18-2
- $2.20-8.80
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 6-Chloro-2-tetralone
17556-18-2
- $6.68
- 97%-99%
- Career Henan Chemical Co
