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4-Chlorobutanal diethyl acetal

CAS No.
6139-83-9
Chemical Name:
4-Chlorobutanal diethyl acetal
Synonyms
NSC 96467;4-CHLOROBUTANAL DIETHYL;4-neoprene diethyl acetal;4-Chloro-1,1-dethoxybutane;4-CHLORO-1,1-DIETHOXY BUTANE;Butane,4-chloro-1,1-diethoxy-;4-CHLORO BUTANAL DIETHYL ACETAL;4-chlorobutyraldehyde diethy acetal;5-chloro-2-(1-ethoxypropoxy)pentanal;4-CHLOROBUTYLRALDEHYDE DIETHYLACETAL
CBNumber:
CB4726908
Molecular Formula:
C8H17ClO2
Molecular Weight:
180.67
MDL Number:
MFCD00671476
MOL File:
6139-83-9.mol
MSDS File:
SDS
Last updated:2025-09-18 19:10:02
Product description Number Pack Size Price
4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) C2717 5g $42
4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) C2717 25g $136
4-Chlorobutyraldehyde Diethyl Acetal C365051 1g $55
4-Chlorobutyraldehyde diethyl acetal FC20211 25g $70
4-Chlorobutyraldehyde diethyl acetal FC20211 50g $130
More product size

4-Chlorobutanal diethyl acetal Properties

Boiling point 208.6°C
Density 0.976
refractive index 1.4260-1.4300
Flash point 51.1°C
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Oil
color Clear Colourless
CAS DataBase Reference 6139-83-9(CAS DataBase Reference)
FDA UNII 22AV7T3NYX

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319
Precautionary statements  P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501
Risk Statements  36/37/38
Safety Statements  26-36/37/39
RIDADR  1993
HS Code  2933.39.9200
HazardClass  3
PackingGroup  III

4-Chlorobutanal diethyl acetal price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C2717 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) 6139-83-9 5g $42 2025-07-31 Buy
TCI Chemical C2717 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) 6139-83-9 25g $136 2025-07-31 Buy
TRC C365051 4-Chlorobutyraldehyde Diethyl Acetal 6139-83-9 1g $55 2021-12-16 Buy
Biosynth Carbosynth FC20211 4-Chlorobutyraldehyde diethyl acetal 6139-83-9 25g $70 2021-12-16 Buy
Biosynth Carbosynth FC20211 4-Chlorobutyraldehyde diethyl acetal 6139-83-9 50g $130 2021-12-16 Buy
Product number Packaging Price Buy
C2717 5g $42 Buy
C2717 25g $136 Buy
C365051 1g $55 Buy
FC20211 25g $70 Buy
FC20211 50g $130 Buy

4-Chlorobutanal diethyl acetal Chemical Properties,Uses,Production

Chemical Properties

Colourless Liquid

Uses

intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan

Uses

4-Chlorobutyraldehyde Diethyl Acetal (cas# 6139-83-9) is a compound useful in organic synthesis. It is used in preparation of Fendiline derivatives as KRAS modulators.

Synthesis

Ethanol

64-17-5

1-Buten-1-ol, 4-chloro-, 1-acetate

763101-16-2

4-Chlorobutanal diethyl acetal

6139-83-9

The general procedure for the synthesis of 4-chlorobutanal diethyl acetal from ethanol and the compound (CAS: 763101-16-2) is as follows: preparation of 4-chlorobutanal diethyl acetal: 13.7 g (0.092 mol) of 4-chloro-1-acetoxy-1-butene, 100 ml (1.70 mol) of 95% ethanol, and about 5 g of triethyl orthoformate were mixed (triethyl orthoformate was added to ensure that the reaction proceeds under anhydrous conditions). Subsequently, 1.40 g of Amberlyst 15 catalyst was added and stirred under reflux conditions for 5 hours. Completion of the reaction was confirmed by gas chromatography (GC) analysis. Upon completion of the reaction, it was manipulated and distilled according to conventional methods to give 10.82 g (65% yield) of the product with a boiling point of 45-50 °C (1 mmHg). Nuclear magnetic resonance (NMR) analysis confirmed that the resulting product was pure 4-chlorobutanal diethyl acetal.

References

[1] Organic Preparations and Procedures International, 2004, vol. 36, # 5, p. 487 - 490
[2] Patent: US2004/192958, 2004, A1. Location in patent: Page 3-4

4-Chlorobutanal diethyl acetal Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 218)Suppliers
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Sichuan Zhuoyu Yantang Technology Co., Ltd.
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Henan Fengda Chemical Co., Ltd
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+8618530059196 sale04@alfachem.cn China 12071 58

View Lastest Price from 4-Chlorobutanal diethyl acetal manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Chlorobutanal diethyl acetal pictures 2025-09-25 4-Chlorobutanal diethyl acetal
6139-83-9
US $50.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-Chlorobutyraldehyde diethyl acetal pictures 2025-09-18 4-Chlorobutyraldehyde diethyl acetal
6139-83-9
US $50.00 / Kg/Bag 1Kg/Bag 99% 5000KG Sichuan Zhuoyu Yantang Technology Co., Ltd.
4-Chlorobutanal diethyl acetal pictures 2019-07-06 4-Chlorobutanal diethyl acetal
6139-83-9
US $100.00 / KG 100G 98% 100g,1KG,5KG,10KG Career Henan Chemical Co

4-Chlorobutanal diethyl acetal Spectrum

4-CHLORO BUTYRALDEHYDE DIETHYL ACETAL 4-CHLORO BUTANAL DIETHYL ACETAL 4-CHLORO-1,1-DIETHOXY BUTANE 4-CHLOROBUTANAL DIETHYL 4-CHLOROBUTYLRALDEHYDE DIETHYLACETAL 4-CHLOROBUTANAL DIETHYL ACETAL (FOR SUMATRIPTAN AND OTHER TRIPTANS),96.0% 4-CHLOROBUTANAL DIETHYL ACETAL (FOR SUMATRIPTAN AND OTHER TRIPTANS) 4-Chloro-1,1-dethoxybutane 4-Chlorobutyraldehyde diethyl aceta 4-neoprene diethyl acetal 5-chloro-2-(1-ethoxypropoxy)pentanal NSC 96467 4-Chloro butaraldehyde diethylacetal 4-chlorobutyraldehyde diethy acetal Butane,4-chloro-1,1-diethoxy- 4-Chlorobutyraldehyde diethyl acetal, 95+% 4-Chlorobutyraldehyde Diethyl Acetal > 4-Chloro Butyaldehyde diethyl Acetal 4-Chloro-1,1-diethoxybutane (4-Chlorobutyraldehyde Diethyl Acetal) 4-Chloro Butyraldehyde Diethyl Acetal (or) 4-Chloro Butanal Diethyl Acetal (or)4-Chloro-1,1-Diethoxy Butane 6139-83-9 4-Chlorobutanal diethyl acetal 6139-83-9 C8H17ClO2 Other Products Aldehyde Labeling Reagents Miscellaneous Reagents