4-Chlorobutanal diethyl acetal
- CAS No.
- 6139-83-9
- Chemical Name:
- 4-Chlorobutanal diethyl acetal
- Synonyms
- NSC 96467;4-CHLOROBUTANAL DIETHYL;4-neoprene diethyl acetal;4-Chloro-1,1-dethoxybutane;4-CHLORO-1,1-DIETHOXY BUTANE;Butane,4-chloro-1,1-diethoxy-;4-CHLORO BUTANAL DIETHYL ACETAL;4-chlorobutyraldehyde diethy acetal;5-chloro-2-(1-ethoxypropoxy)pentanal;4-CHLOROBUTYLRALDEHYDE DIETHYLACETAL
- CBNumber:
- CB4726908
- Molecular Formula:
- C8H17ClO2
- Molecular Weight:
- 180.67
- MDL Number:
- MFCD00671476
- MOL File:
- 6139-83-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | C2717 | 5g | $42 |
| 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | C2717 | 25g | $136 |
| 4-Chlorobutyraldehyde Diethyl Acetal | C365051 | 1g | $55 |
| 4-Chlorobutyraldehyde diethyl acetal | FC20211 | 25g | $70 |
| 4-Chlorobutyraldehyde diethyl acetal | FC20211 | 50g | $130 |
| More product size | |||
| Boiling point | 208.6°C |
|---|---|
| Density | 0.976 |
| refractive index | 1.4260-1.4300 |
| Flash point | 51.1°C |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| color | Clear Colourless |
| CAS DataBase Reference | 6139-83-9(CAS DataBase Reference) |
| FDA UNII | 22AV7T3NYX |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H226-H315-H319 |
| Precautionary statements | P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| RIDADR | 1993 |
| HS Code | 2933.39.9200 |
| HazardClass | 3 |
| PackingGroup | III |
4-Chlorobutanal diethyl acetal price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2717 | 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | 6139-83-9 | 5g | $42 | 2025-07-31 | Buy |
| TCI Chemical | C2717 | 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | 6139-83-9 | 25g | $136 | 2025-07-31 | Buy |
| TRC | C365051 | 4-Chlorobutyraldehyde Diethyl Acetal | 6139-83-9 | 1g | $55 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20211 | 4-Chlorobutyraldehyde diethyl acetal | 6139-83-9 | 25g | $70 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20211 | 4-Chlorobutyraldehyde diethyl acetal | 6139-83-9 | 50g | $130 | 2021-12-16 | Buy |
4-Chlorobutanal diethyl acetal Chemical Properties,Uses,Production
Chemical Properties
Colourless Liquid
Uses
intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan
Uses
4-Chlorobutyraldehyde Diethyl Acetal (cas# 6139-83-9) is a compound useful in organic synthesis. It is used in preparation of Fendiline derivatives as KRAS modulators.
Synthesis
64-17-5
763101-16-2
6139-83-9
The general procedure for the synthesis of 4-chlorobutanal diethyl acetal from ethanol and the compound (CAS: 763101-16-2) is as follows: preparation of 4-chlorobutanal diethyl acetal: 13.7 g (0.092 mol) of 4-chloro-1-acetoxy-1-butene, 100 ml (1.70 mol) of 95% ethanol, and about 5 g of triethyl orthoformate were mixed (triethyl orthoformate was added to ensure that the reaction proceeds under anhydrous conditions). Subsequently, 1.40 g of Amberlyst 15 catalyst was added and stirred under reflux conditions for 5 hours. Completion of the reaction was confirmed by gas chromatography (GC) analysis. Upon completion of the reaction, it was manipulated and distilled according to conventional methods to give 10.82 g (65% yield) of the product with a boiling point of 45-50 °C (1 mmHg). Nuclear magnetic resonance (NMR) analysis confirmed that the resulting product was pure 4-chlorobutanal diethyl acetal.
References
[1] Organic Preparations and Procedures International, 2004, vol. 36, # 5, p. 487 - 490
[2] Patent: US2004/192958, 2004, A1. Location in patent: Page 3-4
4-Chlorobutanal diethyl acetal Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20128 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29831 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 11727 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 4-Chlorobutanal diethyl acetal manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-25 | 4-Chlorobutanal diethyl acetal
6139-83-9
|
US $50.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2019-07-06 | 4-Chlorobutanal diethyl acetal
6139-83-9
|
US $100.00 / KG | 100G | 98% | 100g,1KG,5KG,10KG | Career Henan Chemical Co |
-
- 4-Chlorobutanal diethyl acetal
6139-83-9
- US $50.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-Chlorobutanal diethyl acetal
6139-83-9
- US $100.00 / KG
- 98%
- Career Henan Chemical Co
