4-Chlorobutanal diethyl acetal
- CAS No.
- 6139-83-9
- Chemical Name:
- 4-Chlorobutanal diethyl acetal
- Synonyms
- NSC 96467;4-CHLOROBUTANAL DIETHYL;4-neoprene diethyl acetal;4-Chloro-1,1-dethoxybutane;4-CHLORO-1,1-DIETHOXY BUTANE;Butane,4-chloro-1,1-diethoxy-;4-CHLORO BUTANAL DIETHYL ACETAL;4-chlorobutyraldehyde diethy acetal;5-chloro-2-(1-ethoxypropoxy)pentanal;4-CHLOROBUTYLRALDEHYDE DIETHYLACETAL
- CBNumber:
- CB4726908
- Molecular Formula:
- C8H17ClO2
- Molecular Weight:
- 180.67
- MDL Number:
- MFCD00671476
- MOL File:
- 6139-83-9.mol
- MSDS File:
- SDS
Product description | Number | Pack Size | Price |
4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | C2717 | 5g | $42 |
4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | C2717 | 25g | $136 |
4-Chlorobutyraldehyde Diethyl Acetal | C365051 | 1g | $55 |
4-Chlorobutyraldehyde diethyl acetal | FC20211 | 25g | $70 |
4-Chlorobutyraldehyde diethyl acetal | FC20211 | 50g | $130 |
More product size |
Boiling point | 208.6°C |
---|---|
Density | 0.976 |
refractive index | 1.4260-1.4300 |
Flash point | 51.1°C |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Oil |
color | Clear Colourless |
CAS DataBase Reference | 6139-83-9(CAS DataBase Reference) |
FDA UNII | 22AV7T3NYX |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS02,GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H226-H315-H319 |
Precautionary statements | P210-P233-P240-P241+P242+P243-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501 |
Risk Statements | 36/37/38 |
Safety Statements | 26-36/37/39 |
RIDADR | 1993 |
HS Code | 2933.39.9200 |
HazardClass | 3 |
PackingGroup | III |
4-Chlorobutanal diethyl acetal price More Price(16)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | C2717 | 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | 6139-83-9 | 5g | $42 | 2025-07-31 | Buy |
TCI Chemical | C2717 | 4-Chlorobutyraldehyde Diethyl Acetal >97.0%(GC) | 6139-83-9 | 25g | $136 | 2025-07-31 | Buy |
TRC | C365051 | 4-Chlorobutyraldehyde Diethyl Acetal | 6139-83-9 | 1g | $55 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC20211 | 4-Chlorobutyraldehyde diethyl acetal | 6139-83-9 | 25g | $70 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC20211 | 4-Chlorobutyraldehyde diethyl acetal | 6139-83-9 | 50g | $130 | 2021-12-16 | Buy |
4-Chlorobutanal diethyl acetal Chemical Properties,Uses,Production
Chemical Properties
Colourless Liquid
Uses
intermediate for Sumatriptan, Rizatriptan, Almotriptan, Zolmitriptan
Uses
4-Chlorobutyraldehyde Diethyl Acetal (cas# 6139-83-9) is a compound useful in organic synthesis. It is used in preparation of Fendiline derivatives as KRAS modulators.
Synthesis

64-17-5

763101-16-2

6139-83-9
The general procedure for the synthesis of 4-chlorobutanal diethyl acetal from ethanol and the compound (CAS: 763101-16-2) is as follows: preparation of 4-chlorobutanal diethyl acetal: 13.7 g (0.092 mol) of 4-chloro-1-acetoxy-1-butene, 100 ml (1.70 mol) of 95% ethanol, and about 5 g of triethyl orthoformate were mixed (triethyl orthoformate was added to ensure that the reaction proceeds under anhydrous conditions). Subsequently, 1.40 g of Amberlyst 15 catalyst was added and stirred under reflux conditions for 5 hours. Completion of the reaction was confirmed by gas chromatography (GC) analysis. Upon completion of the reaction, it was manipulated and distilled according to conventional methods to give 10.82 g (65% yield) of the product with a boiling point of 45-50 °C (1 mmHg). Nuclear magnetic resonance (NMR) analysis confirmed that the resulting product was pure 4-chlorobutanal diethyl acetal.
References
[1] Organic Preparations and Procedures International, 2004, vol. 36, # 5, p. 487 - 490
[2] Patent: US2004/192958, 2004, A1. Location in patent: Page 3-4
4-Chlorobutanal diethyl acetal Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sichuan Zhuoyu Yantang Technology Co., Ltd. | +8613288715578 | sales@sichuanzyyt.com | China | 12247 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20175 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21620 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12071 | 58 |
View Lastest Price from 4-Chlorobutanal diethyl acetal manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2025-09-25 | 4-Chlorobutanal diethyl acetal
6139-83-9
|
US $50.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
![]() |
2025-09-18 | 4-Chlorobutyraldehyde diethyl acetal
6139-83-9
|
US $50.00 / Kg/Bag | 1Kg/Bag | 99% | 5000KG | Sichuan Zhuoyu Yantang Technology Co., Ltd. | |
![]() |
2019-07-06 | 4-Chlorobutanal diethyl acetal
6139-83-9
|
US $100.00 / KG | 100G | 98% | 100g,1KG,5KG,10KG | Career Henan Chemical Co |
-
- 4-Chlorobutanal diethyl acetal
6139-83-9
- US $50.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 4-Chlorobutyraldehyde diethyl acetal
6139-83-9
- US $50.00 / Kg/Bag
- 99%
- Sichuan Zhuoyu Yantang Technology Co., Ltd.
-
- 4-Chlorobutanal diethyl acetal
6139-83-9
- US $100.00 / KG
- 98%
- Career Henan Chemical Co