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4-Methoxyphenylacetone

CAS No.
122-84-9
Chemical Name:
4-Methoxyphenylacetone
Synonyms
1-(4-METHOXYPHENYL)-2-PROPANONE;2-Propanone, 1-(4-methoxyphenyl)-;1-(4-Methoxyphenyl)acetone;p-Methoxy;Anisketone;P-ANISYL ACETONE;Methoxyphenylacetone;P-METHOXYBENZYL METHYL KETONE;(6-bromo-3-pyridinyl)methanol;FEMA 2674
CBNumber:
CB4736451
Molecular Formula:
C10H12O2
Molecular Weight:
164.2
MDL Number:
MFCD00008773
MOL File:
122-84-9.mol
MSDS File:
SDS
Last updated:2026-04-03 14:17:14
Product description Number Pack Size Price
4-Methoxyphenylacetone ≥97% 199176 10g $76.5
4-Methoxyphenylacetone ≥97% 199176 50g $101
1-(p-Methoxyphenyl)-2-propanone ≥97% W267406 100g $136
4-Methoxyphenylacetone >97.0%(GC) M0675 25mL $48
4-Methoxyphenylacetone >97.0%(GC) M0675 100mL $95
More product size

4-Methoxyphenylacetone Properties

Melting point <-15 °C
Boiling point 145 °C/25 mmHg (lit.)
Density 1.067 g/mL at 25 °C (lit.)
vapor pressure 1.37Pa at 25℃
refractive index n20/D 1.525(lit.)
FEMA 2674 | 1-(P-METHOXYPHENYL)-2-PROPANONE
FLAVIS Number 07.087 | 4-Methoxyphenylacetone
Flash point 215 °F
storage temp. Sealed in dry,Room Temperature
solubility Methyl Acetate: 50 mg/ml
form Liquid
color Clear light yellow to yellow-green
Odor at 10.00 % in dipropylene glycol. sweet fruity creamy spicy green anisic balsamic licorice fennel
Odor Type fruity
Water Solubility 3.084g/L at 25℃
JECFA Number 813
BRN 2044332
Cosmetics Ingredients Functions PERFUMING
InChI 1S/C10H12O2/c1-8(11)7-9-3-5-10(12-2)6-4-9/h3-6H,7H2,1-2H3
InChIKey WFWKNGZODAOLEO-UHFFFAOYSA-N
SMILES COc1ccc(CC(C)=O)cc1
LogP 1.55 at 25℃
CAS DataBase Reference 122-84-9(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) 1-(P-METHOXYPHENYL)-2-PROPANONE
FDA UNII 6XYW3YJJ33
NIST Chemistry Reference 2-Propanone, 1-(4-methoxyphenyl)-(122-84-9)
EPA Substance Registry System 2-Propanone, 1-(4-methoxyphenyl)- (122-84-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H412-H315
Precautionary statements  P273-P501-P264-P280-P302+P352-P321-P332+P313-P362
PPE Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  23-24/25
WGK Germany  2
RTECS  UC2990000
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29145000
Storage Class 10 - Combustible liquids
Toxicity LD50 orl-rat: 3330 mg/kg FCTXAV 17,857,79
NFPA 704
1
1 0

4-Methoxyphenylacetone price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 199176 4-Methoxyphenylacetone ≥97% 122-84-9 10g $76.5 2026-03-19 Buy
Sigma-Aldrich 199176 4-Methoxyphenylacetone ≥97% 122-84-9 50g $101 2026-03-19 Buy
Sigma-Aldrich W267406 1-(p-Methoxyphenyl)-2-propanone ≥97% 122-84-9 100g $136 2022-05-15 Buy
TCI Chemical M0675 4-Methoxyphenylacetone >97.0%(GC) 122-84-9 25mL $48 2026-03-19 Buy
TCI Chemical M0675 4-Methoxyphenylacetone >97.0%(GC) 122-84-9 100mL $95 2026-03-19 Buy
Product number Packaging Price Buy
199176 10g $76.5 Buy
199176 50g $101 Buy
W267406 100g $136 Buy
M0675 25mL $48 Buy
M0675 100mL $95 Buy

4-Methoxyphenylacetone Chemical Properties,Uses,Production

Aroma

Mild, yet somewhat "gassy" Hawthorne-Anise type odor of good tenacity. It has some resemblance to Methylacetophenone, but is not nearly as harsh or pungent.

Description

l-(p-Methoxyphenyl)-2-propanone has an odor and taste similar to anise. May be obtained by boiling α- or β-anetholglycol with a 20% solution of sulfuric acid, or from l-(p-methoxyphenyl)- propan-l,2-ol by treatment with diluted sulfuric acid.

Chemical Properties

1-(p-Methoxyphenyl)-2-propanone has an odor and taste similar to anise.

Chemical Properties

Pale Yellow Liquid

Occurrence

Reported found in Chinese star anise and in Russian star anise; also reported found in sweet and common fen nel, chervil (Anthriscus cerefolium) and Illicium verum and cherry

Uses

A volatile compound released by flowering plants to attractant insects

Preparation

Obtained by boiling α- or β-anetholglycol with a 2% solution of sulfuric acid, or from 1-(p-methoxyphenyl)-propan-1,2-ol by treatment with diluted sulfuric acid.

Definition

ChEBI: 1-(4-Methoxyphenyl)-2-propanone is an alkylbenzene.

Application

4-Methoxyphenylacetone is used occasionally in perfumes, but more frequent ly in flavor compositions. In fruit and imitation Vanilla, sometimes in Walnut or Cherry flavors, it may be used in traces, equivalent to 0.5 to 5 ppm in the finished product.

Taste threshold values

Taste characteristics at 15 ppm: sweet spicy, with green anisic, minty nuances.

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 1748, 1996 DOI: 10.1021/jo9518314

General Description

Asymmetric amination of 4-methoxyphenylacetone was studied.

Flammability and Explosibility

Not classified

Safety Profile

Moderately toxic by ingestion andother routes. A skin irritant. A flammable liquid.

104-46-1
122-84-9
Synthesis of 4-Methoxyphenylacetone from cis-Anethol
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View Lastest Price from 4-Methoxyphenylacetone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methoxyphenylacetone pictures 2026-03-20 4-Methoxyphenylacetone
122-84-9
US $10.00 / kg 1kg 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
4-Methoxyphenylacetone pictures 2025-07-29 4-Methoxyphenylacetone
122-84-9
US $6.00 / kg 1kg 99% 2000KG/Month HebeiShuoshengImportandExportco.,Ltd
4-Methoxyphenylacetone pictures 2025-06-27 4-Methoxyphenylacetone
122-84-9
US $0.00 / KG 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
4-ANISYL ACETONE 4-METHOXYBENZYL METHYL KETONE 4-METHOXYPHENYLACETONE 4-ACETONYLANISOLE 1-(P-METHOXYPHENYL)-2-PROPANONE 3-(4-METHOXYPHENYL)-2-PROPANONE 1-(4-METHOXYPHENYL)-2-PROPANONE P-METHOXYBENZYL METHYL KETONE (P-METHOXYPHENYL)ACETONE P-ANISYL ACETONE 1-(4-methoxyphenyl)-2-propanon 1-(4-Methoxyphenyl)acetone 1-(Para-methoxyphenyl)-2-propanone 1-(P-METHOXYPHENYL)-2-PROPANONE 97+% 4-METHOXYPHENYLACETONE, 97+% FEMA 2674 PARA-METHOXYPHENYLACETONE ACETONYLANISOLE 1-(4-METHOXY-PHENYL)-PROPAN-2-ONE 4-Methoxyphenylacetone, 98+% p-Methoxy 2-Propanone, 1-(4-methoxyphenyl)- (4-Methoxyphenyl)acetone 98% 4-Methoxybenzyl methyl ketone, 4-Methoxyphenylacetone p-Anisylactone p-Methoxyphenylacetone, 98+% 1-(p-Methoxyphenyl)acetone Methyl(4-methoxybenzyl) ketone 4-Methoxyphenylacetone,4-Methoxybenzyl methyl ketone 1-(p-Methoxyphenyl)-2-propanone,4-Methoxybenzyl methyl ketone, 4-Methoxyphenylacetone 4-Methoxyphenylaceto 4-Methoxyphenylacetone, 98+% 5GR 1-(4-Methoxyphenyl)- (4-METHOXYPHENYL) ACETONE FOR SYNTHESIS Mebeverine IMpurity A The Methoxy phenyl acetone 4-Methoxy BMK 1-(p-methoxyphenyl)-2-propanon 2-Propanone, 1-(p-methoxyphenyl)- 4-Methoxyphenoxyacetone Anisic ketone Anisicketone Anisketone Anisyl methyl ketone anisylmethylketone D-Methoxyphenylacetone Methoxyphenylacetone p-Acetonylanisole 4-Methoxyphenylacetone≥99% (6-bromo-3-pyridinyl)methanol 4-Methoxyphenylacetone> 4-Methoxyphenylacetone CAS 122-84-9 para-anisyl methyl ketone Mebeverine EP Impurity A 4-Methoxyphenylacet Mebeverine Hydrochloride EP Impurity A Mebeverine Hydrochloride Impurity A 122-84-9