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Cbz-N-methyl-L-valine

CAS No.
42417-65-2
Chemical Name:
Cbz-N-methyl-L-valine
Synonyms
Z-MEVAL-OH;Z-L-MEVAL-OH;Cbz-N-Me-Val;Z-N-ME-VALINE;Z-N-ME-VAL-OH;Z-N-Me-L-Val-OH;CBZ-N-ME-VAL-OH;Cbz-N-Me-L-Val-OH;Z-METHYL-L-VALINE;Cbz-N-D-Me-Val-OH
CBNumber:
CB4764597
Molecular Formula:
C14H19NO4
Molecular Weight:
265.3
MDL Number:
MFCD00153397
MOL File:
42417-65-2.mol
MSDS File:
SDS
Last updated:2026-01-13 11:22:12
Product description Number Pack Size Price
Z-N-Me-Val-OH ≥98.0% 00913 500MG $158
Z-N-methyl-L-valine 283786 1g $360
(S)-N-(Benzyloxycarbonyl)-N-methylvaline B286630 5g $225
3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoic acid A7724 5g $267
Z-L-MeVal-OH ZAA1019 5G $337.5
More product size

Cbz-N-methyl-L-valine Properties

Melting point 68-70 °C(lit.)
Boiling point 407.1±34.0 °C(Predicted)
Density 1.166±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
pka 4.01±0.10(Predicted)
form Crystalline Solid
color White
Major Application peptide synthesis
InChI 1S/C14H19NO4/c1-10(2)12(13(16)17)15(3)14(18)19-9-11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3,(H,16,17)/t12-/m0/s1
InChIKey NNEHOKZDWLJKHP-LBPRGKRZSA-N
SMILES CC(C)[C@H](N(C)C(=O)OCc1ccccc1)C(O)=O
CAS DataBase Reference 42417-65-2(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  36/37
WGK Germany  3
Storage Class 11 - Combustible Solids

Cbz-N-methyl-L-valine price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 00913 Z-N-Me-Val-OH ≥98.0% 42417-65-2 500MG $158 2023-01-07 Buy
Usbiological 283786 Z-N-methyl-L-valine 42417-65-2 1g $360 2021-12-16 Buy
TRC B286630 (S)-N-(Benzyloxycarbonyl)-N-methylvaline 42417-65-2 5g $225 2021-12-16 Buy
ApexBio Technology A7724 3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoic acid 42417-65-2 5g $267 2021-12-16 Buy
Iris Biotech GmbH ZAA1019 Z-L-MeVal-OH 42417-65-2 5G $337.5 2021-12-16 Buy
Product number Packaging Price Buy
00913 500MG $158 Buy
283786 1g $360 Buy
B286630 5g $225 Buy
A7724 5g $267 Buy
ZAA1019 5G $337.5 Buy

Cbz-N-methyl-L-valine Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

(S)-N-(Benzyloxycarbonyl)-N-methylvaline has been used as a reactant in the synthesis of a biologically active cyclodepsipeptide destruxin E which is a potent negative regulator of osteoclast morphology.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

Under argon atmosphere, 60% sodium hydroxide (5 g, 0.125 mol) was added in one portion to a stirred mixture of Cbz-L-valine (9.5 g, 0.038) in anhydrous THF (150 mL) at 0??C and stirred simultaneously for 30 minutes. mol) in anhydrous THF (150 mL) and stir for 30 minutes. Iodomethane (20 mL, 0.32 mol) was added and the resulting mixture was stirred overnight at room temperature. Ice water (200mL) was poured into the mixture at 0??C and the resulting mixture was extracted with ether (2x200mL). The aqueous layer was acidified to pH using dilute HCl solution 1.5 and extracted with ethyl acetate (3x200mL). The combined organic extracts were washed with saturated sodium thiosulfate solution (100 mL), dried (Na2SO4) and evaporated in vacuo to give N and evaporated in vacuum to give N-Cbz-N-methyl-L-valine (5 g, 55%) as a colorless viscous oil which can be used in the next step without purification.

Cbz-N-methyl-L-valine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 161)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29833 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Sichuan Jiaying Lai Technology Co.,LTD
18716376478 ycling@enlaibio.com CHINA 302 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8830 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10236 58

Related articles

View Lastest Price from Cbz-N-methyl-L-valine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cbz-N-Me-Val-OH pictures 2020-01-06 Cbz-N-Me-Val-OH
42417-65-2
US $1.00 / g 10g 98% 100kg Sichuan Jiaying Lai Technology Co.,LTD
Cbz-N-methyl-L-valine pictures 2019-09-02 Cbz-N-methyl-L-valine
42417-65-2
US $7.00 / KG 1KG 99% 1000KG Career Henan Chemical Co
  • Cbz-N-Me-Val-OH pictures
  • Cbz-N-Me-Val-OH
    42417-65-2
  • US $1.00 / g
  • 98%
  • Sichuan Jiaying Lai Technology Co.,LTD

Cbz-N-methyl-L-valine Spectrum

BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE BENZYLOXYCARBONYL-N-METHYL-L-VALINE N-Cbz-N-methyl-L-valine 3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoic acid (S)-2-((benzyloxycarbonyl)(methyl)amino)-3-methylbutanoic acid (2S)-2-[[(benzyloxy)carbonyl](Methyl)aMino]-3-Methylbutanoic acid (S)-N-(Benzyloxycarbonyl)-N-Methylvaline CBZ-N-.ALPHA.-METHYL-L-VALINE Cbz-N-Me-L-Val-OH Z-N-Me-Val-OH Z-N-Me-L-Val-OH Z-N-methyl-L-valine≥ 98% (HPLC) Z-L-MEVAL-OH Z-MEVAL-OH Z-METHYL-L-VALINE Z-N-METHYL-L-VALINE Z-N-ME-VALINE Z-N-ME-VAL-OH N-BENZYLOXYCARBONYL-N-METHYL-L-VALINE N-ALPHA-CBZ-N-ALPHA-METHYL-L-VALINE N-ALPHA-CARBOBENZOXY-N-ALPHA-METHYL-L-VALINE N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE Cbz-N-D-Me-Val-OH Z-N-ME-VAL 98.5+% CBZ-N-ME-VAL-OH NALPHA-Benzyloxycarbonyl-N-methyl-L-valine Cbz-N-methyl-L-valine N-(Benzyloxycarbonyl)-N-methylvaline L-Valine, N-methyl-N-[(phenylmethoxy)carbonyl]- (2S)-3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoic acid (2S)-3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoicaci Cbz-N-methyl-L-valine USP/EP/BP Ganciclovir EP Impurity 10 Cbz-N-Me-Val Z-N-α-Methyl-L-valine CBZ- N-methyl valine 42417-65-2 N-Methyl Amino Acids Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives Amino Acid Derivatives