Cbz-N-methyl-L-valine
- CAS No.
- 42417-65-2
- Chemical Name:
- Cbz-N-methyl-L-valine
- Synonyms
- Z-MEVAL-OH;Z-L-MEVAL-OH;Cbz-N-Me-Val;Z-N-ME-VALINE;Z-N-ME-VAL-OH;Z-N-Me-L-Val-OH;CBZ-N-ME-VAL-OH;Cbz-N-Me-L-Val-OH;Z-METHYL-L-VALINE;Cbz-N-D-Me-Val-OH
- CBNumber:
- CB4764597
- Molecular Formula:
- C14H19NO4
- Molecular Weight:
- 265.3
- MDL Number:
- MFCD00153397
- MOL File:
- 42417-65-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Z-N-Me-Val-OH ≥98.0% | 00913 | 500MG | $158 |
| Z-N-methyl-L-valine | 283786 | 1g | $360 |
| (S)-N-(Benzyloxycarbonyl)-N-methylvaline | B286630 | 5g | $225 |
| 3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoic acid | A7724 | 5g | $267 |
| Z-L-MeVal-OH | ZAA1019 | 5G | $337.5 |
| More product size | |||
| Melting point | 68-70 °C(lit.) |
|---|---|
| Boiling point | 407.1±34.0 °C(Predicted) |
| Density | 1.166±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| pka | 4.01±0.10(Predicted) |
| form | Crystalline Solid |
| color | White |
| Major Application | peptide synthesis |
| InChI | 1S/C14H19NO4/c1-10(2)12(13(16)17)15(3)14(18)19-9-11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3,(H,16,17)/t12-/m0/s1 |
| InChIKey | NNEHOKZDWLJKHP-LBPRGKRZSA-N |
| SMILES | CC(C)[C@H](N(C)C(=O)OCc1ccccc1)C(O)=O |
| CAS DataBase Reference | 42417-65-2(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 36/37 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
Cbz-N-methyl-L-valine price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 00913 | Z-N-Me-Val-OH ≥98.0% | 42417-65-2 | 500MG | $158 | 2023-01-07 | Buy |
| Usbiological | 283786 | Z-N-methyl-L-valine | 42417-65-2 | 1g | $360 | 2021-12-16 | Buy |
| TRC | B286630 | (S)-N-(Benzyloxycarbonyl)-N-methylvaline | 42417-65-2 | 5g | $225 | 2021-12-16 | Buy |
| ApexBio Technology | A7724 | 3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoic acid | 42417-65-2 | 5g | $267 | 2021-12-16 | Buy |
| Iris Biotech GmbH | ZAA1019 | Z-L-MeVal-OH | 42417-65-2 | 5G | $337.5 | 2021-12-16 | Buy |
Cbz-N-methyl-L-valine Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
(S)-N-(Benzyloxycarbonyl)-N-methylvaline has been used as a reactant in the synthesis of a biologically active cyclodepsipeptide destruxin E which is a potent negative regulator of osteoclast morphology.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
Under argon atmosphere, 60% sodium hydroxide (5 g, 0.125 mol) was added in one portion to a stirred mixture of Cbz-L-valine (9.5 g, 0.038) in anhydrous THF (150 mL) at 0??C and stirred simultaneously for 30 minutes. mol) in anhydrous THF (150 mL) and stir for 30 minutes. Iodomethane (20 mL, 0.32 mol) was added and the resulting mixture was stirred overnight at room temperature. Ice water (200mL) was poured into the mixture at 0??C and the resulting mixture was extracted with ether (2x200mL). The aqueous layer was acidified to pH using dilute HCl solution 1.5 and extracted with ethyl acetate (3x200mL). The combined organic extracts were washed with saturated sodium thiosulfate solution (100 mL), dried (Na2SO4) and evaporated in vacuo to give N and evaporated in vacuum to give N-Cbz-N-methyl-L-valine (5 g, 55%) as a colorless viscous oil which can be used in the next step without purification.
Cbz-N-methyl-L-valine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8830 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
Related articles
- Cbz-N-methyl-L-valine - Reaction / Application on synthetic works
- (S)-N-(Benzyloxycarbonyl)-N-methylvaline has been used as a reactant in the synthesis of a biologically active peptide. It is ....
- Nov 27,2019
View Lastest Price from Cbz-N-methyl-L-valine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-06 | Cbz-N-Me-Val-OH
42417-65-2
|
US $1.00 / g | 10g | 98% | 100kg | Sichuan Jiaying Lai Technology Co.,LTD | |
![]() |
2019-09-02 | Cbz-N-methyl-L-valine
42417-65-2
|
US $7.00 / KG | 1KG | 99% | 1000KG | Career Henan Chemical Co |
-

- Cbz-N-Me-Val-OH
42417-65-2
- US $1.00 / g
- 98%
- Sichuan Jiaying Lai Technology Co.,LTD
-

- Cbz-N-methyl-L-valine
42417-65-2
- US $7.00 / KG
- 99%
- Career Henan Chemical Co





