4-Quinolinecarboxaldehyde
- CAS No.
- 4363-93-3
- Chemical Name:
- 4-Quinolinecarboxaldehyde
- Synonyms
- QUINOLINE-4-CARBALDEHYDE;4-fomylquinoline;4-FORMYLQUINOLINE;AKOS BBS-00005334;CINCHONINALDEHYDE;TIMTEC-BB SBB004008;RARECHEM AQ NN 0218;4-Quinolinealdehyde;QUINOLINE-4-ALDEHYDE;4-QUINOLINECARBALDEHYDE
- CBNumber:
- CB4773795
- Molecular Formula:
- C10H7NO
- Molecular Weight:
- 157.17
- MDL Number:
- MFCD00006781
- MOL File:
- 4363-93-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Quinolinecarboxaldehyde 97% | 176966 | 2.5g | $75.3 |
| 4-Quinolinecarboxaldehyde 97% | 176966 | 10g | $246 |
| 4-Quinolinecarboxaldehyde >97.0%(GC)(T) | Q0061 | 1g | $38 |
| 4-Quinolinecarboxaldehyde >97.0%(GC)(T) | Q0061 | 5g | $103 |
| 4-Quinolinecarboxaldehyde >97.0%(GC)(T) | Q0061 | 25g | $348 |
| More product size | |||
| Melting point | 45-52 °C (lit.) |
|---|---|
| Boiling point | 131-133°C 5mm |
| Density | 1.1599 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | 2.95±0.13(Predicted) |
| form | Crystalline Powder, Chunks, or Solid |
| color | Off-white to yellow-brown |
| Water Solubility | Slightly soluble in water. |
| Sensitive | Air Sensitive |
| BRN | 113072 |
| InChI | InChI=1S/C10H7NO/c12-7-8-5-6-11-10-4-2-1-3-9(8)10/h1-7H |
| InChIKey | MGCGJBXTNWUHQE-UHFFFAOYSA-N |
| SMILES | N1C2C(=CC=CC=2)C(C=O)=CC=1 |
| CAS DataBase Reference | 4363-93-3(CAS DataBase Reference) |
| FDA UNII | 3A0K4YX051 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340+P312 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 37/38-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Quinolinecarboxaldehyde price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 176966 | 4-Quinolinecarboxaldehyde 97% | 4363-93-3 | 2.5g | $75.3 | 2025-07-31 | Buy |
| Sigma-Aldrich | 176966 | 4-Quinolinecarboxaldehyde 97% | 4363-93-3 | 10g | $246 | 2025-07-31 | Buy |
| TCI Chemical | Q0061 | 4-Quinolinecarboxaldehyde >97.0%(GC)(T) | 4363-93-3 | 1g | $38 | 2025-07-31 | Buy |
| TCI Chemical | Q0061 | 4-Quinolinecarboxaldehyde >97.0%(GC)(T) | 4363-93-3 | 5g | $103 | 2025-07-31 | Buy |
| TCI Chemical | Q0061 | 4-Quinolinecarboxaldehyde >97.0%(GC)(T) | 4363-93-3 | 25g | $348 | 2025-07-31 | Buy |
4-Quinolinecarboxaldehyde Chemical Properties,Uses,Production
Chemical Properties
yellow to yellow-brown crystalline powder
Occurrence
The common presence of 4-quinolinecarboxaldehyde in honey from Galicia (northwest of Spain). As opposed to other quinoline carboxylic acid derivatives, the 4- quinolinecarboxaldehyde species has not been correlated with the anti-diabetic properties of honey; nevertheless, it appears to be active against intestinal bacteria.
Uses
4-Quinolinecarboxaldehyde was used in the synthesis of lepidylamines. It also shows antimicrobial activity toward human intestinal bacteria such as Clostridium perfringens.
Synthesis Reference(s)
The Journal of Organic Chemistry, 35, p. 841, 1970 DOI: 10.1021/jo00828a074
Synthesis
491-35-0
4363-93-3
The general procedure for the synthesis of 4-quinolinecarboxaldehyde from 4-methylquinoline was as follows: 5.0 g (35 mmol) of 4-methylquinoline and 5.0 g (45 mmol) of selenium dioxide were dissolved in toluene under argon protection and heated to reflux for 24 hours. After completion of the reaction, the reaction mixture was diluted with dichloromethane, washed sequentially with saturated saline and dried with anhydrous magnesium sulfate. After concentration under reduced pressure, the reaction was purified by silica gel column chromatography using a solvent mixture of hexane and ethyl acetate (4:1, v/v) as eluent to give 4.0 g (73% yield) of the target product 4-quinolinecarboxaldehyde as a solid. Nuclear magnetic resonance hydrogen spectroscopy (1H NMR) data: δ 10.54 (s, 1H), 9.22 (d, J = 4.3 Hz, 1H), 9.04 (d, J = 8.6 Hz, 1H), 8.24 (d, J = 8.2 Hz, 1H), 7.84 (t, J = 7.6 Hz, 1H), 7.81 (d, J = 4.3 Hz, 1H), 7.76 (t , J = 8.0 Hz, 1H). Nuclear magnetic resonance carbon (13C NMR) data: δ 193.1, 150.7, 149.5, 137.0, 130.4, 130.3, 129.6, 126.0, 124.7, 124.1. mass spectrometry (electrospray ionization) data: m/z 158.0 (100%) ([M + H]+), 130.2.
References
[1] Tamara Rodríguez-Cabo. “Time-of-flight accurate mass spectrometry identification of quinoline alkaloids in honey.” Analytical and Bioanalytical Chemistry 407 20 (2015): 6159–6170.
4-Quinolinecarboxaldehyde Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hongxiong | +undefined18915499068 | Suzhouhongxiong@163.com | China | 120 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29833 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8830 | 58 |
View Lastest Price from 4-Quinolinecarboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-12-01 | 4-Quinolinecarboxaldehyde
4363-93-3
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
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2025-11-18 | 4-Quinolinecarboxaldehyde
4363-93-3
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
![]() |
2021-07-09 | 4-Quinolinecarbaldehyde
4363-93-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-

- 4-Quinolinecarboxaldehyde
4363-93-3
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-

- 4-Quinolinecarboxaldehyde
4363-93-3
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-

- 4-Quinolinecarbaldehyde
4363-93-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd






