ChemicalBook >> CAS DataBase List >>4-Quinolinecarboxaldehyde

4-Quinolinecarboxaldehyde

CAS No.
4363-93-3
Chemical Name:
4-Quinolinecarboxaldehyde
Synonyms
QUINOLINE-4-CARBALDEHYDE;4-fomylquinoline;4-FORMYLQUINOLINE;AKOS BBS-00005334;CINCHONINALDEHYDE;TIMTEC-BB SBB004008;RARECHEM AQ NN 0218;4-Quinolinealdehyde;QUINOLINE-4-ALDEHYDE;4-QUINOLINECARBALDEHYDE
CBNumber:
CB4773795
Molecular Formula:
C10H7NO
Molecular Weight:
157.17
MDL Number:
MFCD00006781
MOL File:
4363-93-3.mol
MSDS File:
SDS
Last updated:2026-01-13 11:20:44
Product description Number Pack Size Price
4-Quinolinecarboxaldehyde 97% 176966 2.5g $75.3
4-Quinolinecarboxaldehyde 97% 176966 10g $246
4-Quinolinecarboxaldehyde >97.0%(GC)(T) Q0061 1g $38
4-Quinolinecarboxaldehyde >97.0%(GC)(T) Q0061 5g $103
4-Quinolinecarboxaldehyde >97.0%(GC)(T) Q0061 25g $348
More product size

4-Quinolinecarboxaldehyde Properties

Melting point 45-52 °C (lit.)
Boiling point 131-133°C 5mm
Density 1.1599 (rough estimate)
refractive index 1.5000 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka 2.95±0.13(Predicted)
form Crystalline Powder, Chunks, or Solid
color Off-white to yellow-brown
Water Solubility Slightly soluble in water.
Sensitive Air Sensitive
BRN 113072
InChI InChI=1S/C10H7NO/c12-7-8-5-6-11-10-4-2-1-3-9(8)10/h1-7H
InChIKey MGCGJBXTNWUHQE-UHFFFAOYSA-N
SMILES N1C2C(=CC=CC=2)C(C=O)=CC=1
CAS DataBase Reference 4363-93-3(CAS DataBase Reference)
FDA UNII 3A0K4YX051
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340+P312
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  37/38-36/37/38
Safety Statements  24/25-36-26-36/37/39
WGK Germany  3
10
HazardClass  IRRITANT
HS Code  29334900
Storage Class 11 - Combustible Solids
Hazard Classifications Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

4-Quinolinecarboxaldehyde price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 176966 4-Quinolinecarboxaldehyde 97% 4363-93-3 2.5g $75.3 2025-07-31 Buy
Sigma-Aldrich 176966 4-Quinolinecarboxaldehyde 97% 4363-93-3 10g $246 2025-07-31 Buy
TCI Chemical Q0061 4-Quinolinecarboxaldehyde >97.0%(GC)(T) 4363-93-3 1g $38 2025-07-31 Buy
TCI Chemical Q0061 4-Quinolinecarboxaldehyde >97.0%(GC)(T) 4363-93-3 5g $103 2025-07-31 Buy
TCI Chemical Q0061 4-Quinolinecarboxaldehyde >97.0%(GC)(T) 4363-93-3 25g $348 2025-07-31 Buy
Product number Packaging Price Buy
176966 2.5g $75.3 Buy
176966 10g $246 Buy
Q0061 1g $38 Buy
Q0061 5g $103 Buy
Q0061 25g $348 Buy

4-Quinolinecarboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

yellow to yellow-brown crystalline powder

Occurrence

The common presence of 4-quinolinecarboxaldehyde in honey from Galicia (northwest of Spain). As opposed to other quinoline carboxylic acid derivatives, the 4- quinolinecarboxaldehyde species has not been correlated with the anti-diabetic properties of honey; nevertheless, it appears to be active against intestinal bacteria.

Uses

4-Quinolinecarboxaldehyde was used in the synthesis of lepidylamines. It also shows antimicrobial activity toward human intestinal bacteria such as Clostridium perfringens.

Synthesis Reference(s)

The Journal of Organic Chemistry, 35, p. 841, 1970 DOI: 10.1021/jo00828a074

Synthesis

4-methylquinoline

491-35-0

4-Quinolinecarboxaldehyde

4363-93-3

The general procedure for the synthesis of 4-quinolinecarboxaldehyde from 4-methylquinoline was as follows: 5.0 g (35 mmol) of 4-methylquinoline and 5.0 g (45 mmol) of selenium dioxide were dissolved in toluene under argon protection and heated to reflux for 24 hours. After completion of the reaction, the reaction mixture was diluted with dichloromethane, washed sequentially with saturated saline and dried with anhydrous magnesium sulfate. After concentration under reduced pressure, the reaction was purified by silica gel column chromatography using a solvent mixture of hexane and ethyl acetate (4:1, v/v) as eluent to give 4.0 g (73% yield) of the target product 4-quinolinecarboxaldehyde as a solid. Nuclear magnetic resonance hydrogen spectroscopy (1H NMR) data: δ 10.54 (s, 1H), 9.22 (d, J = 4.3 Hz, 1H), 9.04 (d, J = 8.6 Hz, 1H), 8.24 (d, J = 8.2 Hz, 1H), 7.84 (t, J = 7.6 Hz, 1H), 7.81 (d, J = 4.3 Hz, 1H), 7.76 (t , J = 8.0 Hz, 1H). Nuclear magnetic resonance carbon (13C NMR) data: δ 193.1, 150.7, 149.5, 137.0, 130.4, 130.3, 129.6, 126.0, 124.7, 124.1. mass spectrometry (electrospray ionization) data: m/z 158.0 (100%) ([M + H]+), 130.2.

References

[1] Tamara Rodríguez-Cabo. “Time-of-flight accurate mass spectrometry identification of quinoline alkaloids in honey.” Analytical and Bioanalytical Chemistry 407 20 (2015): 6159–6170.

91-22-5
4363-93-3
Synthesis of 4-Quinolinecarboxaldehyde from Quinoline
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View Lastest Price from 4-Quinolinecarboxaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Quinolinecarboxaldehyde pictures 2025-12-01 4-Quinolinecarboxaldehyde
4363-93-3
US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Quinolinecarboxaldehyde  pictures 2025-11-18 4-Quinolinecarboxaldehyde
4363-93-3
US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
4-Quinolinecarbaldehyde pictures 2021-07-09 4-Quinolinecarbaldehyde
4363-93-3
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
AKOS BBS-00005334 4-FORMYLQUINOLINE 4-QUINOLINECARBALDEHYDE 4-QUINOLINECARBOXALDEHYDE ASINEX-REAG BAS 01118292 CINCHONINALDEHYDE QUINOLINE-4-ALDEHYDE QUINOLINE-4-CARBALDEHYDE QUINOLINE-4-CARBOXALDEHYDE RARECHEM AQ NN 0218 TIMTEC-BB SBB004008 4-Quinolinealdehyde 4-QUINOLINECARBOXALDEHYDE 95% Quinoline-4-carboxaldehyde,99% 4-fomylquinoline 4-Quinolinecarboxaldehyde ,97% Quinoline-4-carboxaldehyde, 97+% 4-Quinolinecarboxaldehyde,95% 4-Quinolinecarboxaldehyde ,94% Cinchoninaldehyde 4-Formylquinoline 4-Quinolinecarboxaldehyde > 4-Quinolinecarboxaldehyde ISO 9001:2015 REACH 4-quinoline formaldehyde 4363-93-3 C9H6NCOH Building Blocks Heterocyclic Building Blocks Quinolinecarboxylic Acids, etc. Quinolines ALDEHYDE Quinolinecarboxylic Acids, etc. Quinolines Quinoline Quinoline Derivertives