VU 6001966
- CAS No.
- 2009052-76-8
- Chemical Name:
- VU 6001966
- Synonyms
- VU 6001966;4-(4-Fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide;2-Pyridinecarboxamide, 4-(4-fluorophenyl)-5-[(1-methyl-1H-pyrazol-3-yl)methoxy]-
- CBNumber:
- CB48202929
- Molecular Formula:
- C17H15FN4O2
- Molecular Weight:
- 326.33
- MDL Number:
- MOL File:
- 2009052-76-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
VU 6001966 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0078899 | VU6001966 99.89% | 2009052-76-8 | 5mg | $791 | 2026-06-04 | Buy |
| aablocks | AA01LQBW | 4-(4-Fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide >98% | 2009052-76-8 | 5mg | $847 | 2026-05-30 | Buy |
| Arctom | HY-120717 | VU6001966 99.89% | 2009052-76-8 | 5mg | $694 | 2026-05-26 | Buy |
| Tocris | 6928 | VU6001966 ≥98%(HPLC) | 2009052-76-8 | 5 | $245 | 2021-12-16 | Buy |
VU 6001966 Chemical Properties, Uses, Production
Uses
VU6001966 (compound 15m) is a potent and cross the blood-brain barrier mGlu2 (metabotropic glutamate receptor 2) negative allosteric modulator with IC50s of 78 nM and >30 μM for mGlu2 and mGlu3, respectively. VU6001966 can serve as an mGlu2 PET tracer[1].
IC 50
mGluR2: 78 nM (IC50); mGluR3: >30 μM (IC50)
storage
Store at -20°C
References
[1] Bollinger KA,et al. Design and Synthesis of mGlu2 NAMs with Improved Potency and CNS Penetration Based on a Truncated Picolinamide Core. ACS Med Chem Lett. 2017 Aug 3;8(9):919-924. DOI:10.1021/acsmedchemlett.7b00279
VU 6001966 Preparation Products And Raw materials
Raw materials
Preparation Products
VU 6001966 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 964 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50068 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
