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ChemicalBook >> CAS DataBase List >>2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)-

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)-

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- Structure
2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- structure
CAS No.
1799506-07-2
Chemical Name:
2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)-
Synonyms
HaloPROTAC3;VH285-PEG4-C4-Cl;Halo PROTAC-3|||HaloPROTAC 3|||HaloPROTAC-3;(2S,4R)-N-(2-(2-(2-(2-((6- Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4- methylthiazol-5-yl)benzyl)-4-hydroxy-1-((S)-3-methyl-2-(1- oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide;(2S,4R)-N-({2-[2-(2-{2-[(6-chlorohexyl)oxy]ethoxy}ethoxy)ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl}methyl)-4-hydroxy-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide;2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)-
CBNumber:
CB48344045
Molecular Formula:
C41H55ClN4O8S
Molecular Weight:
799.42
MDL Number:
MOL File:
1799506-07-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:36:44
Request For Quotation

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- Properties

Boiling point 952.2±65.0 °C(Predicted)
Density 1.250±0.06 g/cm3(Predicted)
pka 14.07±0.40(Predicted)
form Viscous Liquid
color Colorless to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H303-H315-H319
Precautionary statements  P264-P280-P302+P352-P312-P337+P313-P305+P351+P338-P362+P364-P332+P313

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth ZWC50607 HaloPROTAC3 1799506-07-2 25mg $1310 2026-06-05 Buy
Biosynth ZWC50607 HaloPROTAC3 1799506-07-2 50mg $1822.5 2026-06-05 Buy
ChemScene CS-0094830 VH285-PEG4-C4-Cl 96.49% 1799506-07-2 5mg $368 2026-06-04 Buy
ChemScene CS-0094830 VH285-PEG4-C4-Cl 96.49% 1799506-07-2 10mg $596 2026-06-04 Buy
ChemScene CS-0094830 VH285-PEG4-C4-Cl 96.49% 1799506-07-2 25mg $1300 2026-06-04 Buy
Product number Packaging Price Buy
ZWC50607 25mg $1310 Buy
ZWC50607 50mg $1822.5 Buy
CS-0094830 5mg $368 Buy
CS-0094830 10mg $596 Buy
CS-0094830 25mg $1300 Buy

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- Chemical Properties, Uses, Production

Uses

VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and 16-atom-length linker. The connector of linker is Halogen group. VH285-PEG4-C4-Cl incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. VH285-PEG4-C4-Cl is a highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM. VH285-PEG4-C4-Cl is able to induce 90 % degradation of GFP-Halotag at 625 nM. VH285-PEG4-C4-Cl binds to VHL with an IC50 of 0.54 μM[1].

IC 50

VHL

References

[1] Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7. DOI:10.1021/acschembio.5b00442

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- Suppliers

Global Suppliers ( 33)
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Han-Xiang Chemical Co., Ltd. 17754423994 candy@biochempartner.com China 3057 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4566 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 10233 58
Nantong Hi-Future Biotechnology Co., Ltd +86-0513; 18051384581 sales@chemhifuture.com China 3077 58
Wuhan Augda Biotechnology Co., Ltd 15071299552 262933239@qq.com China 7200 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Han-Xiang Chemical Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
ShangHai ChuanQian Chemcial Technique Centre 58
cjbscvictory 58
Nantong Hi-Future Biotechnology Co., Ltd 58
Wuhan Augda Biotechnology Co., Ltd 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from 2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
HaloPROTAC3 pictures 2026-05-14 HaloPROTAC3
1799506-07-2
 $112.00-455.00 98.66% 10g TargetMol Chemicals Inc.
  • HaloPROTAC3 pictures
  • HaloPROTAC3
    1799506-07-2
  • $112.00-455.00
  • 98.66%
  • TargetMol Chemicals Inc.

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- Spectrum

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)-(1799506-07-2)1HNMR

1799506-07-2 (2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)-) Related Search:

(2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide Pomalidomide-PEG3-N3 Pentanediamide, N1-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-N5-[19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-4,7,10-trioxa-14-azanonadec-1-yl]- CAS:2722697-82-5 (S,R,S)-AHPC-Me-C6-NH2
2,6-Piperidinedione, 3-[4-[[2-(2-aminoethoxy)ethyl]amino]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-, hydrochloride (1:2)

1of2

2-Pyrrolidinecarboxamide, N-[[2-[2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]ethoxy]-4-(4-methyl-5-thiazolyl)phenyl]methyl]-1-[(2S)-2-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-3-methyl-1-oxobutyl]-4-hydroxy-, (2S,4R)- HaloPROTAC3 (2S,4R)-N-(2-(2-(2-(2-((6- Chlorohexyl)oxy)ethoxy)ethoxy)ethoxy)-4-(4- methylthiazol-5-yl)benzyl)-4-hydroxy-1-((S)-3-methyl-2-(1- oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide Halo PROTAC-3|||HaloPROTAC 3|||HaloPROTAC-3 (2S,4R)-N-({2-[2-(2-{2-[(6-chlorohexyl)oxy]ethoxy}ethoxy)ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl}methyl)-4-hydroxy-1-[(2S)-3-methyl-2-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide VH285-PEG4-C4-Cl 1799506-07-2 C41H55ClN4O8S