3-ETHYNYL-BENZOIC ACID METHYL ESTER
- CAS No.
- 10602-06-9
- Chemical Name:
- 3-ETHYNYL-BENZOIC ACID METHYL ESTER
- Synonyms
- Methyl 3-ethynylbenzoate;3-(Methoxycarbonyl)phenylacetylene;3-ETHYNYL-BENZOIC ACID METHYL ESTER;Benzoic acid, 3-ethynyl-, methyl ester
- CBNumber:
- CB4846352
- Molecular Formula:
- C10H8O2
- Molecular Weight:
- 160.17
- MDL Number:
- MFCD08703579
- MOL File:
- 10602-06-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 3-ethynylbenzoate 95% | AS39850 | 1g | $33 |
| Methyl 3-ethynylbenzoate 98% | OR41056 | 1g | $43 |
| Methyl 3-ethynylbenzoate 95% | AS39850 | 5g | $128 |
| Methyl 3-ethynylbenzoate 98% | OR41056 | 5g | $157 |
| Methyl 3-ethynylbenzoate 98% | OR41056 | 10g | $297 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2916310090 |
3-ETHYNYL-BENZOIC ACID METHYL ESTER price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS39850 | Methyl 3-ethynylbenzoate 95% | 10602-06-9 | 1g | $33 | 2026-06-04 | Buy |
| Apolloscientific | OR41056 | Methyl 3-ethynylbenzoate 98% | 10602-06-9 | 1g | $43 | 2026-06-04 | Buy |
| Activate Scientific | AS39850 | Methyl 3-ethynylbenzoate 95% | 10602-06-9 | 5g | $128 | 2026-06-04 | Buy |
| Apolloscientific | OR41056 | Methyl 3-ethynylbenzoate 98% | 10602-06-9 | 5g | $157 | 2026-06-04 | Buy |
| Apolloscientific | OR41056 | Methyl 3-ethynylbenzoate 98% | 10602-06-9 | 10g | $297 | 2026-06-04 | Buy |
3-ETHYNYL-BENZOIC ACID METHYL ESTER Chemical Properties,Uses,Production
Uses
Methyl 3-ethynylbenzoate is a useful research chemical.
Synthesis
67-56-1
914943-91-2
10602-06-9
Tert-butyl 3-ethynylbenzoate (117) (1.50 g, 9.37 mmol) was dissolved in anhydrous dichloromethane (DCM) (70 mL) and trifluoroacetic acid (TFA) (35.9 mL, 488 mmol) was added slowly. The reaction mixture was stirred at room temperature for 3 hours and then concentrated under vacuum. Toluene was then added and concentrated again under vacuum to give a light yellow solid. The solid was dissolved in methanol (50 mL) and concentrated again. Concentrated sulfuric acid (about 1 mL) was added and the resulting solution was stirred at 85°C for 20 hours. After completion of the reaction, it was cooled to room temperature and the volatiles were removed under vacuum. The residue was diluted with ethyl acetate (EtOAc) (200 mL) and slowly neutralized with saturated aqueous sodium bicarbonate (NaHCO3) (100 mL). The organic and aqueous layers were separated and the aqueous layer was further extracted with ethyl acetate (200 mL). The organic layers were combined, washed sequentially with water (100 mL) and brine (100 mL), dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated in vacuo to afford methyl 3-alkynylbenzoate (131) (1.136 g, 96% overall yield in two steps) as a pale yellow solid. The product was confirmed by 1H NMR (400 MHz, CDCl3): δ 8.17 (t, J = 1.5 Hz, 1H), 8.03-8.00 (m, 1H), 7.66 (dt, J = 7.7, 1.4 Hz, 1H), 7.41 (td, J = 7.8, 0.4 Hz, 1H), 3.93 (s, 3H), 3.12 (s, 1H) . the LCMS analysis method C showed a retention time of 5.84 min.
References
[1] Patent: WO2014/27199, 2014, A1. Location in patent: Page/Page column 75
[2] Patent: WO2012/110773, 2012, A1. Location in patent: Page/Page column 73
3-ETHYNYL-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
View Lastest Price from 3-ETHYNYL-BENZOIC ACID METHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-07-10 | 3-ETHYNYL-BENZOIC ACID METHYL ESTER
10602-06-9
|
$1.00 | 1KG | 98% | 150KG | Career Henan Chemical Co |
-
- 3-ETHYNYL-BENZOIC ACID METHYL ESTER
10602-06-9
- $1.00
- 98%
- Career Henan Chemical Co
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