2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
![2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Structure](CAS/GIF/627899-90-5.gif)
- CAS No.
- 627899-90-5
- Chemical Name:
- 2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- Synonyms
- 4-(3-dimethylaminopropoxy)benzeneboronic acidolester;4-[3-(Dimethylamino)propoxy]phenylboronic acid, pinacol ester;4-[3-(Dimethylamino)propoxy]benzene boronic acid, pinacol ester;2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;N,N-dimethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]1-Propanamine;N,N-Dimethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propan-1-amine;1-Propanamine, N,N-dimethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]-
- CBNumber:
- CB4854023
- Molecular Formula:
- C17H28BNO3
- Molecular Weight:
- 305.22
- MDL Number:
- MFCD09702395
- MOL File:
- 627899-90-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314 | |||||||||
| Precautionary statements | P280-P309+P311 | |||||||||
| Hazard Codes | C | |||||||||
| Hazard Note | Corrosive | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR12268 | 4-[3-(Dimethylamino)propoxy]benzeneboronic acid, pinacol ester ≥95% | 627899-90-5 | 250mg | $33 | 2026-06-04 | Buy |
| Apolloscientific | OR12268 | 4-[3-(Dimethylamino)propoxy]benzeneboronic acid, pinacol ester ≥95% | 627899-90-5 | 1g | $98 | 2026-06-04 | Buy |
| Matrix Scientific | 200062 | N,N-Dimethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propan-1-amine | 627899-90-5 | 250.00mg | $55 | 2026-05-18 | Buy |
| Matrix Scientific | 200062 | N,N-Dimethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propan-1-amine | 627899-90-5 | 1.00g | $126 | 2026-05-18 | Buy |
| Matrix Scientific | 200062 | N,N-Dimethyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]propan-1-amine | 627899-90-5 | 5.00g | $376 | 2026-05-18 | Buy |
2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Chemical Properties,Uses,Production
Synthesis
76579-64-1
61676-62-8
![2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane](/CAS/GIF/627899-90-5.gif)
627899-90-5
GENERAL STEPS: To a 100 mL flame-dried two-neck flask was added 3-(4-bromophenoxy)-N,N-dimethyl-1-propanamine (3.0 g, 11.6 mmol) and freshly distilled tetrahydrofuran (80 mL). The resulting solution was cooled to -78 °C and n-butyllithium (8.7 mL, 13.9 mmol, 1.6 M hexane solution) was added dropwise over 10 min under nitrogen protection. The reaction mixture was stirred at -78 °C for 1 hour. Subsequently, isopropyl pinacol borate (2.6 g, 13.9 mmol) was quickly added and the resulting mixture was slowly warmed to room temperature for 24 hours. Upon completion of the reaction, the mixture was poured into 50 mL of water and extracted with chloroform (300 mL). The organic layers were combined, washed with saturated brine and dried over anhydrous magnesium sulfate. The solvent was removed by rotary evaporation and the residue was purified by silica gel column chromatography (eluent: ethyl acetate/dichloromethane) to afford the target product as a light yellow oil (1.6 g, yield: 45.0%). The product was characterized as follows: 1H NMR (400 MHz, CDCl3, Me4Si): δ = 7.77 (d, 2H, J = 8.8 Hz), 6.90 (d, 2H, J = 8.8 Hz), 3.94 (t, 2H, J = 6.4 Hz), 2.46 (t, 2H, J = 6.8 Hz), 2.26 (s, 6H), 1.88 (m , 2H, J = 6.8 Hz), 1.25 (s, 12H).13C NMR (100 MHz, CDCl3, Me4Si): 161.57, 136.73, 113.41, 83.13, 74.40, 66.02, 54.09, 45.42, 27.43, 25.00.Calculated elemental analysis values ( C17H28BNO3): C, 66.90; H, 9.25; N, 4.59. Measured values: C, 66.73; H, 9.23; N, 4.63. IR (KBr, cm-1): 2981, 2936, 2816, 2716, 1566, 1463, 1281, 1245.
References
[1] Dyes and Pigments, 2015, vol. 113, p. 210 - 218
[2] Patent: KR2015/122308, 2015, A. Location in patent: Paragraph 0094; 0095; 0098; 0099
2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Preparation Products And Raw materials
Raw materials
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Preparation Products
2-{4-[3-(dimethylamino)propoxy]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
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| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
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