isocil
- CAS No.
- 314-42-1
- Chemical Name:
- isocil
- Synonyms
- H-82;isocil;H82sclc;Isoprocil;Herbicide 82;5-BROMO-3-ISOPROPYL-6-METHYLURACIL;NCI-H82 Cells Line[H82 Cells Line];5-bromo-6-methyl-3-propan-2-yl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 5-bromo-6-methyl-3-(1-methylethyl)-
- CBNumber:
- CB4879231
- Molecular Formula:
- C8H11BrN2O2
- Molecular Weight:
- 247.09
- MDL Number:
- MFCD01677120
- MOL File:
- 314-42-1.mol
- MSDS File:
- SDS
| Melting point | 158-159° |
|---|---|
| Density | 1.6046 (rough estimate) |
| refractive index | 1.5140 (estimate) |
| Water Solubility | 2.15g/L(25 ºC) |
| FDA UNII | BTE61I85CW |
| EPA Substance Registry System | Isocil (314-42-1) |
isocil Chemical Properties,Uses,Production
Chemical Properties
Crystals.Soluble in absolute alcohol.
Uses
Herbicide.
Definition
ChEBI: Isocil is a member of pyrimidines and an organohalogen compound.
Production Methods
A detailed manufacturing route for isocil is not available in open literature but its structure and chemical class make its industrial production reasonably inferable from standard uracil herbicide synthesis. Isocil is a brominated, alkyl substituted uracil, so commercial manufacture would begin with construction of the 6 methyluracil core, typically via condensation of a beta ketoester with urea under acidic or thermal conditions to form the pyrimidinedione ring. The isopropyl substituent at the 3 position would then be introduced through controlled alkylation of the uracil nitrogen using an isopropyl halide or sulphate ester. Finally, selective bromination at the 5 position, using a brominating agent such as bromine or N bromosuccinimide under conditions that preserve the sensitive heterocycle, yields the final herbicide, which is then purified and formulated.
Hazard
Toxic by ingestion.
Mechanism of action
Photosynthesis inhibitor
Pesticide Type
Herbicide
isocil Preparation Products And Raw materials
Raw materials
Preparation Products
isocil Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Jiegu Biotechnology Co., Ltd. | 021-51698675 | sales@jiejiegroup.com | China | 8195 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9925 | 58 |
| Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 029-029-81120477 17792793610 | 1033@dideu.com | China | 9990 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shanghai Jingfeng Biotechnology Co., Ltd | 34661275 17301805756 | 69787182@qq.com | China | 7988 | 58 |
| Pricella | 027-88237608 15608650710 | sales@procell.com.cn | China | 959 | 58 |
| Shanghai Yaji Biotechnology Co., Ltd. | 021-34661276 15317085058 | 1278329642@qq.com | China | 6359 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
