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Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- structure

CAS No.: 2390475-81-5

Chemical Name:: Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-

Synonyms: EB-42486;EB-42486, 10 mM in DMSO;EB-42486,EB 42486,inhibit,EB42486,Inhibitor,LRRK2,Leucine-rich repeat kinase 2;4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)tetrazolo[1,5-a]pyrimidine-6-carboxamide;4,5,7,7-Tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxamide;Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-;4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-4H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine-6-carboxamide

CBNumber:: CB49378052

Molecular Formula:: C22H22N8O

Molecular Weight:: 414.46

MDL Number:

MOL File:: 2390475-81-5.mol

Last updated:2025-04-17 18:22:24

Request For Quotation

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Properties

Density	1.41±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 250 mg/mL (603.19 mM; Need ultrasonic)
form	Solid
pka	11.92±0.40(Predicted)
color	Off-white to light yellow

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Chemical Properties,Uses,Production

Uses

EB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50 < 0.2 nM).

Biological Activity

EB-42486 is a novel, potent, and highly selective G2019S-LRRK2 inhibitor (IC50 < 0.2 nM).

References

[1]. Garofalo AW, et al. Selective Inhibitors of G2019S-LRRK2 Kinase Activity. J Med Chem. 2020 Dec 10;63(23):14821-14839.

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Suppliers

Global( 25)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32268	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9642	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38663	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
Shanghai Maiev Biotech Co.,Ltd	+86-13671830408 +86-13671830408	maievbiotech2@163.com	China	79	58
Finetech Industry Limited	027-87465837 19945049750	sales@finetechnology-ind.com	China	9650	58
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4611	55
ATK CHEMICAL COMPANY LIMITED	021-51619050 13301662590	mandy@atkchemical.com	China	9053	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9803	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Finetech Industry Limited	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai Maiev Biotech Co.,Ltd	58
Finetech Industry Limited	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	55
Shanghai EFE Biological Technology Co., Ltd.	58

View Lastest Price from Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	EB-42486 2390475-81-5	US $64.00-158.00 / mg		98.06%	10g	TargetMol Chemicals Inc.

EB-42486
2390475-81-5
US $64.00-158.00 / mg
98.06%
TargetMol Chemicals Inc.

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- Spectrum

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-(2390475-81-5)¹HNMR

Tetrazolo[1,5-a]pyrimidine-6-carboxamide, 4,7-dihydro-4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)- EB-42486 EB-42486,EB 42486,inhibit,EB42486,Inhibitor,LRRK2,Leucine-rich repeat kinase 2 4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)tetrazolo[1,5-a]pyrimidine-6-carboxamide 4,5,7,7-Tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxamide 4,5,7,7-tetramethyl-N-(3-phenyl-1H-indazol-5-yl)-4H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine-6-carboxamide EB-42486, 10 mM in DMSO 2390475-81-5