6-(Bromomethyl)-2,4-pteridinediamine hydrobromide
- CAS No.
- 52853-40-4
- Chemical Name:
- 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide
- Synonyms
- 6-(Bromomethyl)-2,4-diaminopteridine Hydrobromide;2,4-pteridinediaMine, 6-(broMoMethyl)-, hydrobroMide;Nsc253943;Methotrexate Impurity 15;Methotrexate Impurity 16;Methotrexate Impurity 17 HBr;6-Bromoethyl-pteridine-2,4-diamine;6-BROMOMETHYL-PTERIDINE-2,4-DIAMINE HBR;2, 4-diaMino-6-(broMoMethyl)-pteridine HCL;6-Bromomethyl-pteridine-2,4-diamine hydrobromide
- CBNumber:
- CB51010881
- Molecular Formula:
- C7H8Br2N6
- Molecular Weight:
- 335.99
- MDL Number:
- MFCD09833976
- MOL File:
- 52853-40-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | FB19250 | 25g | $343.75 |
| 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | FB19250 | 50g | $550 |
| 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | FB19250 | 100g | $963 |
| 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | FB19250 | 250g | $1720 |
| 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | 093056 | 250.00mg | $21 |
| More product size | |||
| Melting point | >195°C (dec.) |
|---|---|
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Light Brown to Brown |
| InChI | InChI=1S/C7H7BrN6.BrH/c8-1-3-2-11-6-4(12-3)5(9)13-7(10)14-6;/h2H,1H2,(H4,9,10,11,13,14);1H |
| InChIKey | KMQIBGKVZDBGAH-UHFFFAOYSA-N |
| SMILES | NC1=NC(N)=NC2=NC=C(CBr)N=C12.Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
6-(Bromomethyl)-2,4-pteridinediamine hydrobromide price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FB19250 | 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | 52853-40-4 | 25g | $343.75 | 2026-06-04 | Buy |
| Biosynth | FB19250 | 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | 52853-40-4 | 50g | $550 | 2026-06-04 | Buy |
| Biosynth | FB19250 | 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | 52853-40-4 | 100g | $963 | 2026-06-04 | Buy |
| Biosynth | FB19250 | 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | 52853-40-4 | 250g | $1720 | 2026-06-04 | Buy |
| Matrix Scientific | 093056 | 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide | 52853-40-4 | 250.00mg | $21 | 2026-05-18 | Buy |
6-(Bromomethyl)-2,4-pteridinediamine hydrobromide Chemical Properties,Uses,Production
Description
6-(Bromomethyl)-2,4-pteridinediamine hydrobromide is a potent inhibitor of the enzyme nitroaldolase (EC 1.2.1.22) and has been shown to inhibit cell growth in murine leukemia cells. This reaction is mediated by the addition of bromide to isobutyl esters, leading to a benzyl ester intermediate which undergoes an electrophilic attack on nitroaldolase. The mechanism of action for this drug involves the inhibition of membrane transport and chloride ion influx, which are necessary for the proliferation of tumor cells. 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide also inhibits DNA synthesis through its effects on thymidylate synthase, preventing nucleotide production from thymine and dihydrofolate reductase activity.
Chemical Properties
Light Brown Solid
Uses
6-(Bromomethyl)-2,4-pteridinediamine hydrobromide can be used as organic synthesis intermediate and pharmaceutical intermediate.
Application
6-(Bromomethyl)-2,4-pteridinediamine Hydrobromide (Technical Grade) is a useful research chemical used in the preparation of novel methotrexate derivatives as antirheumatic agents as well as the preparation of pteridine reductase inhibitors.
6-(Bromomethyl)-2,4-pteridinediamine hydrobromide Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14035 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21533 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Lotusland Life Sciences | +8615821988213 | info@longyupharma.com | China | 2411 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29094 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15050 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9539 | 58 |
View Lastest Price from 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-31 | 6-(Bromomethyl)-2,4-pteridinediamine Hydrobromide
52853-40-4
|
1KG | 90%min | 100KGS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2019-07-06 | 6-BROMOMETHYL-PTERIDINE-2,4-DIAMINE HBR
52853-40-4
|
$1.00 | 1KG | 98% | 1tons | Career Henan Chemical Co |
-
- 6-(Bromomethyl)-2,4-pteridinediamine Hydrobromide
52853-40-4
- 90%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 6-BROMOMETHYL-PTERIDINE-2,4-DIAMINE HBR
52853-40-4
- $1.00
- 98%
- Career Henan Chemical Co
