Talinolol
- CAS No.
- 57460-41-0
- Chemical Name:
- Talinolol
- Synonyms
- Cordanum;rac-Talinolol ;Racemic talinolol;Talinolol, 10 mM in DMSO;1-(4-(Cyclohexylureido)phenoxy)-3-(tert-butylamino)-2-propanol;1-(4-Cyclohexylureidophenoxy)-2-hydroxy-3-tert-butylaminopropane;1-(3-(3-Cyclohexylureido)phenoxy)-3-(tert-butylamino)-2-propanol;1-(4-(3-(tert-butylaMino)-2-hydroxypropoxy)phenyl)-3-cyclohexylu;1-(4-(3-(tert-butylamino)-2-hydroxypropoxy)phenyl)-3-cyclohexylurea;1-(2-(3-(tert-butylamino)-2-hydroxypropoxy)phenyl)-3-cyclohexylurea
- CBNumber:
- CB51073789
- Molecular Formula:
- C20H33N3O3
- Molecular Weight:
- 363.49
- MDL Number:
- MFCD00864592
- MOL File:
- 57460-41-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Talinolol ≥95% (HPLC) | SML3412 | 5MG | $71.4 |
| Talinolol ≥95% (HPLC) | SML3412 | 25MG | $288 |
| (±)-Talinolol ≥95% | 16116 | 1mg | $49 |
| (±)-Talinolol ≥95% | 16116 | 5mg | $202 |
| (±)-Talinolol ≥95% | 16116 | 10mg | $376 |
| Melting point | 160-162°C |
|---|---|
| Boiling point | 520.0±50.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.82±0.20(Predicted) |
| color | White to Pale Pink |
| InChI | InChI=1S/C20H33N3O3/c1-20(2,3)21-13-17(24)14-26-18-11-9-16(10-12-18)23-19(25)22-15-7-5-4-6-8-15/h9-12,15,17,21,24H,4-8,13-14H2,1-3H3,(H2,22,23,25) |
| InChIKey | MXFWWQICDIZSOA-UHFFFAOYSA-N |
| SMILES | N(C1CCCCC1)C(NC1=CC=C(OCC(O)CNC(C)(C)C)C=C1)=O |
| FDA UNII | 3S82268BKG |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| WGK Germany | WGK 3 |
| HazardClass | IRRITANT |
| Storage Class | 11 - Combustible Solids |
| Toxicity | LD50 in rats, mice (mg/kg): 1180, 593 orally; 54.3, 74.7 i.p.; 29.7, 25.0 i.v. (Femmer) |
Talinolol price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3412 | Talinolol ≥95% (HPLC) | 57460-41-0 | 5MG | $71.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML3412 | Talinolol ≥95% (HPLC) | 57460-41-0 | 25MG | $288 | 2026-04-30 | Buy |
| Cayman Chemical | 16116 | (±)-Talinolol ≥95% | 57460-41-0 | 1mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 16116 | (±)-Talinolol ≥95% | 57460-41-0 | 5mg | $202 | 2026-04-30 | Buy |
| Cayman Chemical | 16116 | (±)-Talinolol ≥95% | 57460-41-0 | 10mg | $376 | 2026-04-30 | Buy |
Talinolol Chemical Properties,Uses,Production
Description
(±)-
Chemical Properties
Off-White to Pale Pink Solid
Uses
Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.
Definition
ChEBI: Talinolol is a member of ureas.
in vivo
Talinolol (20 mg/kg; i.p.) plasma and liver AUC0-5 h are increased by Zosuquidar administration[2].
Bioavailability of Talinolol can be enhanced by coadministration with grapefruit juice (GFJ) in rats[3].
IC 50
Beta-1 adrenergic receptor
References
[1] abmann i. the actions of talinolol, a β1-selective beta blocker, in cardiac arrhythmia and acute myocardial infarction[j]. current medical research and opinion, 2008, 13(6): 325-342.
[2] trausch b, oertel r, richter k, et al. disposition and bioavailability of the β1‐adrenoceptor antagonist talinolol in man[j]. biopharmaceutics & drug disposition, 1995, 16(5): 403-414.
Talinolol Preparation Products And Raw materials
Raw materials
Preparation Products
Talinolol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9949 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Tianjin Zhongtian Xinchuang Technology Co., Ltd. | 13312191509 | 1932163312@qq.com | China | 235 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 89686 | 60 |
