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Ethyl 4-bromophenylacetate

CAS No.
14062-25-0
Chemical Name:
Ethyl 4-bromophenylacetate
Synonyms
ethyl 2-(4-broMophenyl)acetate;4-bromophenylacetic acid ethyl ester;Ethyl 4-Bromophenyl;4-broMoethyl acetate;ETHYL 4-BROMOPHENYLACETATE;ETHYL P-BROMOPHENYLACETATE;2-(4-bromophenyl)butanoate;4-Bromophenylacetate ethyl;Ethyl4-Bromophenylacetate>Ethyl 4-bromophenylacetate,99%
CBNumber:
CB5109173
Molecular Formula:
C10H11BrO2
Molecular Weight:
243.1
MDL Number:
MFCD00016333
MOL File:
14062-25-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:56:13
Product description Number Pack Size Price
Ethyl 4-bromophenylacetate 97% 631353 5g $72.5
Ethyl 4-bromophenylacetate 97% 631353 25g $75.4
Ethyl 4-Bromophenylacetate >98.0%(GC) E0903 5g $25
Ethyl 4-Bromophenylacetate >98.0%(GC) E0903 25g $64
4-Bromophenylacetic acid ethyl ester ≥99%(GC) 27403 5G $18.53
More product size

Ethyl 4-bromophenylacetate Properties

Melting point 29-33 °C(lit.)
Boiling point 88-90°C 0,35mm
Density 1.389±0.06 g/cm3(Predicted)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
form Liquid or Low Melting Solid
color Clear colorless to pale yellow
InChI InChI=1S/C10H11BrO2/c1-2-13-10(12)7-8-3-5-9(11)6-4-8/h3-6H,2,7H2,1H3
InChIKey ZFDCWHPNBWPPHG-UHFFFAOYSA-N
SMILES C1(CC(OCC)=O)=CC=C(Br)C=C1
CAS DataBase Reference 14062-25-0(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22
Safety Statements  36
WGK Germany  3
Hazard Note  Irritant
HS Code  29163990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
NFPA 704
1
2 0

Ethyl 4-bromophenylacetate price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 631353 Ethyl 4-bromophenylacetate 97% 14062-25-0 5g $72.5 2026-04-30 Buy
Sigma-Aldrich 631353 Ethyl 4-bromophenylacetate 97% 14062-25-0 25g $75.4 2026-04-30 Buy
TCI Chemical E0903 Ethyl 4-Bromophenylacetate >98.0%(GC) 14062-25-0 5g $25 2026-04-30 Buy
TCI Chemical E0903 Ethyl 4-Bromophenylacetate >98.0%(GC) 14062-25-0 25g $64 2026-04-30 Buy
Chem-Impex 27403 4-Bromophenylacetic acid ethyl ester ≥99%(GC) 14062-25-0 5G $18.53 2026-05-19 Buy
Product number Packaging Price Buy
631353 5g $72.5 Buy
631353 25g $75.4 Buy
E0903 5g $25 Buy
E0903 25g $64 Buy
27403 5G $18.53 Buy

Ethyl 4-bromophenylacetate Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to pale yellow liquid

Uses

4-Bromo-benzeneacetic Acid Ethyl Ester is used to prepare highly selective and orally active Lysophosphatidic Acid (LPA) receptor-1 antagonists with potent activity on human lung fibroblasts.

Synthesis

Ethanol

64-17-5

4-Bromophenylacetic acid

1878-68-8

Ethyl 4-bromophenylacetate

14062-25-0

Preparation of the intermediate 1-bromo-4-(2-methoxy-2-methyldienyl)benzene (1AG-1): 2-(4-bromophenyl)acetic acid (75 g, 340 mmol) was suspended in ethanol (341 mL). Concentrated sulfuric acid (0.682 mL, 12.79 mmol) was added slowly and the reaction mixture was subsequently heated to reflux and maintained for 24 hours. Upon completion of the reaction, the mixture was concentrated to remove the solvent. The residue was diluted with ether and saturated sodium bicarbonate solution for acid-base neutralization. The organic and aqueous layers were carefully separated and the organic layer was subsequently washed with brine and dried over sodium sulfate. The dried organic phase was filtered and the filtrate was concentrated to give ethyl 2-(4-bromophenyl)acetate (80.2 g, 97% yield) as an off-white solid.

References

[1] Patent: WO2010/86820, 2010, A1. Location in patent: Page/Page column 53
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 21, p. 6665 - 6681
[3] Patent: US2013/79320, 2013, A1. Location in patent: Paragraph 0473; 0474
[4] Patent: WO2013/45451, 2013, A1. Location in patent: Paragraph 51
[5] European Journal of Medicinal Chemistry, 2014, vol. 86, p. 714 - 723

1878-68-8
14062-25-0
Synthesis of Ethyl 4-bromophenylacetate from 4-Bromophenylacetic acid
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View Lastest Price from Ethyl 4-bromophenylacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 4-bromophenylacetate pictures 2025-06-27 Ethyl 4-bromophenylacetate
14062-25-0
1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
Ethyl 4-bromophenylacetate pictures 2022-01-27 Ethyl 4-bromophenylacetate
14062-25-0
1KG 99.1% 100 tons Honest Joy Holdings Limited
Ethyl 4-bromophenylacetate pictures 2019-07-10 Ethyl 4-bromophenylacetate
14062-25-0
$1.00 1KG 98% 150KG Career Henan Chemical Co

Ethyl 4-bromophenylacetate Spectrum

ETHYL P-BROMOPHENYLACETATE ETHYL 4-BROMOPHENYLACETATE 4-bromophenylacetic acid ethyl ester Ethyl 4-bromophenylacetate 99% Ethyl 4-bromophenylacetate,99% 2-(4-bromophenyl)butanoate Ethyl p-Bromophenylacetate Ethyl Ethyl 4-bromophenylacetate ,97% 1-Bromo-4-(2-ethoxy-2-oxoethyl)benzene Ethyl 4-broMophenylacetate, 99% 5GR 4-broMoethyl acetate Ethyl 2-(4-broMophenyl)acetate, 95+% 4-Bromophenylacetic acid ethyl ester, Ethyl 2-(4-bromophenyl)ethanoate Ethyl4-Bromophenylacetate> Benzeneacetic acid, 4-bromo-, ethyl ester Ethyl 4-bromophenylacetate, 95% (Custo 4-Bromophenylacetate ethyl Ethyl 4-Bromophenyl ethyl 2-(4-broMophenyl)acetate 14062-25-0 Esters Building Blocks C10 to C11 Carbonyl Compounds Organic Building Blocks Pyrimidines Aromatic Esters C10 to C11 Carbonyl Compounds Esters Acids and Derivatives