ChemicalBook >> CAS DataBase List >>9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE

CAS No.
3056-18-6
Chemical Name:
9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE
Synonyms
BINO-004;NSC 76763;Regadenoson Impurity 42;2-Chloroadenosine impurity B;2',3',5'-Tri-O-Acetyl-2,6-Dichloropurine;2,6-DCl-2′,,3′,,5′,-TAc-PuR;2,6-Dichloro-2',3',5'-triacetyl-purineriboside;2,6-Dichloro-2',3',5'-triacetyl-purine riboside;9-[2,3,5-tri-O-acetyl--D-ribofuranosyl]-2,6-dichloropurine;2,6-dichloro-9-(2,3,5-tri-O-acetylpentofuranosyl)-9H-purine
CBNumber:
CB51092672
Molecular Formula:
C16H16Cl2N4O7
Molecular Weight:
447.23
MDL Number:
MFCD02093101
MOL File:
3056-18-6.mol
MSDS File:
SDS
Last updated:2026-05-28 01:56:59
Product description Number Pack Size Price
2,6-Dichloro-9-(2’,3’,5’-tri-O-acetyl-ß-D-ribofuranosyl)purine D3532-70 500mg $375
2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 295721 500mg $382
2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 295721 1g $542
2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 295721 2g $761
2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 295721 5g $1047

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE Properties

Melting point 158-159°C
Boiling point 555.3±60.0 °C(Predicted)
Density 1.69±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), DMSO (Slightly)
form Solid
pka -1.40±0.10(Predicted)
color Off-White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H312-H302-H332
Precautionary statements  P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
HS Code  29335990

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological D3532-70 2,6-Dichloro-9-(2’,3’,5’-tri-O-acetyl-ß-D-ribofuranosyl)purine 3056-18-6 500mg $375 2026-06-03 Buy
Usbiological 295721 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 3056-18-6 500mg $382 2026-06-03 Buy
Usbiological 295721 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 3056-18-6 1g $542 2026-06-03 Buy
Usbiological 295721 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 3056-18-6 2g $761 2026-06-03 Buy
Usbiological 295721 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Asreported 3056-18-6 5g $1047 2026-06-03 Buy
Product number Packaging Price Buy
D3532-70 500mg $375 Buy
295721 500mg $382 Buy
295721 1g $542 Buy
295721 2g $761 Buy
295721 5g $1047 Buy

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE Chemical Properties,Uses,Production

Chemical Properties

Off-White to Pale Yellow Solid

Uses

Protected nucleoside.

Synthesis

2',3',5'-Tri-O-acetyl-2-aMino-6-chloropurine Riboside

16321-99-6

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE

3056-18-6

Synthesis of (2R,3R,4R,5R)-2-(acetyloxymethyl)-5-(2-amino-6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate from (2R,3R,4R,5R)-2-(acetyloxymethyl)-5-(2,6-dichloro-9H-purin-9-yl)tetrahydrofuran-3,4-diacetic acid di-ester The general procedure was as follows: isoamyl nitrite (165 g, 1.41 mol) was dissolved in dichloromethane (500 mL) and stirred at 0 to 5 °C. Subsequently, trimethylchlorosilane (76 g, 0.70 mol) was added, followed by a solution of Compound IV (100 g, 0.234 mol) in dichloromethane (500 mL). The mixture was added dropwise to the above reaction masterbatch, and after the dropwise addition was completed, the reaction continued to be stirred at the same temperature for 1 hour. After completion of the reaction, saturated sodium sulfite solution was added for quenching and partitioning. The organic phase obtained by separation was washed sequentially with aqueous sodium bicarbonate solution and saturated brine, then dried with anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure until no fraction evaporated. The residue was recrystallized by addition of dichloromethane (100 mL) and n-heptane (350 mL) to give the yellow solid compound V, 2,6-dichloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine (86 g, 82% yield).

References

[1] Journal of Organic Chemistry, 2003, vol. 68, # 2, p. 666 - 669
[2] Canadian Journal of Chemistry, 1981, vol. 59, # 17, p. 2608 - 2611
[3] Patent: CN106397516, 2017, A. Location in patent: Paragraph 0029; 0030; 0080; 0081; 0082; 0083
[4] Journal of Medicinal Chemistry, 1992, vol. 35, # 24, p. 4557 - 4561
[5] Journal of Organic Chemistry, 2002, vol. 67, # 19, p. 6788 - 6796

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE Preparation Products And Raw materials

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE Suppliers

Global( 92)Suppliers
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Moxin Chemicals
+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21587 55
Nanjing Baifuli Technology Co., Ltd.
+86-15335185688 sales@unisyn.cn CHINA 332 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
AFINE CHEMICALS LIMITED
+86-0571-85134551 sales@afinechem.com China 15083 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9539 58
NewCan Biotech Limited
+86-571-86912261 19975279805 sales@newcanbio.com China 9985 58
Wuhu Nuowei chemistry Co., Ltd.
+86-0553-2911116-802 +86-18055326116 sales1@nuowei-chem.com China 1627 58
TargetMol Chemicals Inc.
+1-781-999-5354; support@targetmol.com United States 39039 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43333 58

View Lastest Price from 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6-Dichloro-2',3',5'-triacetyl-purine riboside pictures 2026-05-11 2,6-Dichloro-2',3',5'-triacetyl-purine riboside
3056-18-6
10g TargetMol Chemicals Inc.
Regadenoson Impurity29 pictures 2025-12-16 Regadenoson Impurity29
3056-18-6
10mg 99%+ HPLC 1000 Moxin Chemicals
9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE pictures 2020-03-05 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE
3056-18-6
$1.00 1KG 98% HPLC 10 tons Career Henan Chemical Co

9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE Spectrum

NSC 76763 [3,4-Bis(acetyloxy)-5-(2,6-dichloro-9H-purin-9-yl)oxolan-2-yl]methyl acetate [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,6-dichloropurin-9-yl)oxolan-2-yl]methyl acetate 2',3',5'-Tri-O-Acetyl-2,6-Dichloropurine [3,4-BIS(ACETYLOXY)-5-(2,6-DICHLOROPURIN-9-YL)OXOLAN-2-YL]METHYL ACETATE 2R,3R,4R,5R)-4-(acetyloxy)-2-[(acetyloxy)methyl]-5-(2,6-dichloro-9H-purin-9-yl)tetrahydro-3-furanyl acetate 9H-Purine, 2,6-dichloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,6-dichloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 9-[2,3,5-TRI-O-ACETYL-SS-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE 2,6-DICHLORO-9-(2,3,5-TRI-O-ACETYL-B-D-RIBOFURANOSYL)-9H-PURINE [4-acetyloxy-5-(acetyloxymethyl)-2-(2,6-dichloropurin-9-yl)oxolan-3-yl] acetate [4-acetyloxy-5-(acetyloxymethyl)-2-(2,6-dichloropurin-9-yl)oxolan-3-yl] ethanoate acetic acid [4-acetoxy-5-(acetoxymethyl)-2-(2,6-dichloropurin-9-yl)tetrahydrofuran-3-yl] ester 9-[2,3,5-TRI-O-ACETYL-BETA-D-RIBOFURANOSYL]-2,6-DICHLOROPURINE 9-[2,3,5-tri-O-acetyl--D-ribofuranosyl]-2,6-dichloropurine [3,4-diacetyloxy-5-(2,6-dichloropurin-9-yl)oxolan-2-yl]methyl acetate BINO-004 2,6-Dichloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine 9H-Purine,2,6-dichloro-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)- 2,6-Dichloro-2',3',5'-triacetyl-purine riboside 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine 2,6-dichloro-9-(2,3,5-tri-O-acetylpentofuranosyl)-9H-purine 2,6-Dichloro-2',3',5'-triacetyl-purineriboside 2-Chloroadenosine impurity B 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine Regadenoson Impurity 42 2,6-DCl-2′,,3′,,5′,-TAc-PuR 2,6-Dichloro-9-(2′,3′,5′-tri-O-acetyl-β-D-ribofuranosyl)purine, CAS 3056-18-6 D-Xylofuranose, 3,5-bis-O-(phenylmethyl)-, 1,2-diacetate (ACI) 3056-18-6 C16H16Cl2N4O7 Bases & Related Reagents Heterocycles Nucleotides