Asiatic acid
- CAS No.
- 464-92-6
- Chemical Name:
- Asiatic acid
- Synonyms
- 2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACID;NSC 166063;ASIATIC ACID;Asiantic acid;ASIATICA ACID;ASIATIC ACID(P);DaMMarolic acid;Asiatic acid-RM;Asiatic Acid >Snow oxalic acid
- CBNumber:
- CB5109340
- Molecular Formula:
- C30H48O5
- Molecular Weight:
- 488.7
- MDL Number:
- MFCD00238541
- MOL File:
- 464-92-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Asiatic acid analytical standard | 89773 | 10mg | $484 |
| Asiatic acid 97% | 546712 | 500mg | $300 |
| Asiatic Acid | A2475 | 200MG | $95 |
| Asiatic Acid ≥95% | 11818 | 50mg | $41 |
| Asiatic Acid ≥95% | 11818 | 500mg | $183 |
| More product size | |||
| Melting point | 325-330 °C(lit.) |
|---|---|
| Boiling point | 609.4±55.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| RTECS | YU9580000 |
| storage temp. | 2-8°C |
| solubility | methanol: soluble1mg/mL, clear, colorless |
| pka | 4.66±0.70(Predicted) |
| form | powder |
| color | white |
| biological source | Centella asiatica |
| Water Solubility | Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING LIGHT STABILIZER |
| InChIKey | JXSVIVRDWWRQRT-UYDOISQJSA-N |
| SMILES | C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |
| LogP | 5.748 (est) |
| CAS DataBase Reference | 464-92-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 9PA5A687X5 |
| UNSPSC Code | 85151701 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H413 | |||||||||
| Precautionary statements | P501-P273 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29181990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazardous Substances Data | 464-92-6(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
Asiatic acid price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 89773 | Asiatic acid analytical standard | 464-92-6 | 10mg | $484 | 2026-03-19 | Buy |
| Sigma-Aldrich | 546712 | Asiatic acid 97% | 464-92-6 | 500mg | $300 | 2026-03-19 | Buy |
| TCI Chemical | A2475 | Asiatic Acid | 464-92-6 | 200MG | $95 | 2026-03-19 | Buy |
| Cayman Chemical | 11818 | Asiatic Acid ≥95% | 464-92-6 | 50mg | $41 | 2024-03-01 | Buy |
| Cayman Chemical | 11818 | Asiatic Acid ≥95% | 464-92-6 | 500mg | $183 | 2024-03-01 | Buy |
Asiatic acid Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the whole grass of Centella asiatica (Centella asiatica), a plant of the genus Leiogangen, family Umbelliferae.
Uses
wound healing, experimental carcinogen
Uses
Asiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells.
Uses
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. It is a starting material for asiatic acid derivative synthesis for use as anticancer agents, glycogen phosphorylase inhibitors and and hepatoprotectants.
Definition
ChEBI: A pentacyclic triterpenoid that is ursane substituted by a carboxy group at position 28 and hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). It is isolated from Symplocos lancifolia and Vateria indica and exhibits anti-angiogenic activity.
General Description
Asiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.
Biochem/physiol Actions
Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties.
Synthesis
16830-15-2
464-92-6
1) 1 g of (2α,3β,4α)-3,4-dihydroxy-6-(hydroxymethyl)-5-((3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 10,11-dihydroxy-9-(hydroxymethyl)-hexamethyl- Eicosanoid-4a-carboxylic acid ester (asiaticoside), 4.3×10^-2 mol sodium dodecyl sulfate and 0.02 mol NaOH were mixed, water was added to 1 L, and stirred until completely dissolved to obtain a mixed solution. The hydrolysis reaction was carried out at room temperature (25°C) and atmospheric pressure (1 atm) for 15 min to obtain the hydrolysate.2) The pH of the hydrolysate was adjusted to 5.0 with 1 M HCl solution and allowed to stand for 30 min, followed by filtration and collection of the precipitate.3) The precipitate was dissolved in 70% (v/v) aqueous ethanol at a ratio of 1 g:30 mL and filtered to remove insoluble matter. Crystallization was carried out by adding 16 times the volume of distilled water to the filtrate and allowed to stand overnight for complete crystallization. The crystallized product was collected by filtration and dried to constant weight in a vacuum drying oven at 40°C to obtain cumaric acid white crystals of 0.445 g. The product was analyzed by high-performance liquid chromatography (HPLC) with a purity of 95.8% and a yield of 93.08%.
target
TNF-α | IFN-γ | IL Receptor | Caspase | p21 | NOS | NADPH-oxidase | NO | HMG-CoA reductase | COX
References
[1] Patent: CN106349319, 2017, A. Location in patent: Paragraph 0017-0032
[2] Patent: WO2009/89365, 2009, A2. Location in patent: Page/Page column 6-7
[3] Steroids, 2015, vol. 96, p. 44 - 49
[4] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 20, p. 4500 - 4504
[5] RSC Advances, 2016, vol. 6, # 67, p. 62890 - 62906
Asiatic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 | sales@zhswyy.com | China | 240 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 477 | 58 |
| Shaanxi Xianhe Biotech Co., Ltd | +86-17709210191; +8617709210191 | Jerry@xhobio.com | China | 906 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13815 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
Related articles
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- Nov 11，2025
View Lastest Price from Asiatic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | Asiatic acid
464-92-6
|
US $40.00-79.00 / mg | 98.01% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-22 | Asiatic acid
464-92-6
|
US $0.00 / KG | 1KG | 75%; 85%; 95% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2026-04-16 | Asiatic acid
464-92-6
|
US $0.00 / kg | 1kg | 0.99 | 1000kg | Shaanxi Xianhe Biotech Co., Ltd |
-
- Asiatic acid
464-92-6
- US $40.00-79.00 / mg
- 98.01%
- TargetMol Chemicals Inc.
-
- Asiatic acid
464-92-6
- US $0.00 / KG
- 75%; 85%; 95% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Asiatic acid
464-92-6
- US $0.00 / kg
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
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