ChemicalBook >> CAS DataBase List >>ANTI-HUMAN DNA TOPOISOMERASE I
ANTI-HUMAN DNA TOPOISOMERASE I
- CAS No.
- Chemical Name:
- ANTI-HUMAN DNA TOPOISOMERASE I
- Synonyms
- ANTI-DNA TOPOISOMERASE I;Anti-DNA topoisomerase 1;ANTI-HUMAN DNA TOPOISOMERASE I;Anti-TOP1 antibody produced in rabbit
- CBNumber:
- CB5111589
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01867508
- MOL File:
- Mol file
Last updated:2026-01-13 13:16:49
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
|---|---|
| WGK Germany | WGK 1 |
| Storage Class | 10 - Combustible liquids |
ANTI-HUMAN DNA TOPOISOMERASE I price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA019039 | Anti-TOP1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $667 | 2026-04-30 | Buy | |
| Sigma-Aldrich | HPA019039 | Anti-TOP1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $282 | 2023-06-20 | Buy | |
| American Custom Chemicals Corporation | ATB0016993 | ANTI-DNA TOPOISOMERASE I 95.00% | 5MG | $500.39 | 2021-12-16 | Buy |
ANTI-HUMAN DNA TOPOISOMERASE I Chemical Properties, Uses, Production
Biological Activity
DNA topoisomerases cause single (type-1) or double (type-2) strand DNA breaks, leading to DNA relaxation. They control DNA replication, transcription, recombination and chromatin remodeling. TOP1 (DNA topoisomerase 1) binding to the promoter areas induces nucleosome disassembly, histone acetylation and gene expression. Camptothecin is a non-competitive TOP1 inhibitor. TOP1 also controls alternative splicing through phosphorylation of serine/arginine-rich proteins. It is up-regulated in non-small cell lung cancer (NSCLC).
ANTI-HUMAN DNA TOPOISOMERASE I Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN DNA TOPOISOMERASE I Suppliers
Global Suppliers ( 3)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Merck KGaA | -- | ordercn@merckgroup.com | China | 6376 | 58 |
| Riedel-de Haen AG | -- | United States | 6624 | 87 | |
| BD Biosciences | -- | United States | 5012 | 82 |
| Supplier | Advantage |
|---|---|
| Merck KGaA | 58 |
| Riedel-de Haen AG | 87 |
| BD Biosciences | 82 |
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