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Cyclobutanecarboxylic acid

Cyclobutanecarboxylic acid structure

CAS No.: 3721-95-7

Chemical Name:: Cyclobutanecarboxylic acid

Synonyms: Cyclobutylcarboxylic acid;cyclobutanecarboxylate;Cyclobutane-1-carboxylic acid;obutanecarboxyL;Ring butyl forMate;RARECHEM AL BO 0291;Cyclo-butyl formic a;Cyclobutancarbonsure;CYCLO-BUTYL FORMIC ACID;Cyclobutanecarbonyl acid

CBNumber:: CB5113033

Molecular Formula:: C5H8O2

Molecular Weight:: 100.12

MDL Number:: MFCD00001323

MOL File:: 3721-95-7.mol

MSDS File:: SDS

Last updated:2026-01-27 10:27:28

Product description	Number	Pack Size	Price
Cyclobutanecarboxylic acid 98%	C95609	5g	$38.66
Cyclobutanecarboxylic acid 98%	C95609	25g	$75.5
Cyclobutanecarboxylic Acid >97.0%(GC)(T)	C0888	10g	$35
Cyclobutanecarboxylic Acid >97.0%(GC)(T)	C0888	25g	$67
Cyclobutanecarboxylic acid 98%	C95609	100g	$205
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Cyclobutanecarboxylic acid Properties

Melting point	−7.5 °C(lit.)
Boiling point	195 °C(lit.)
Density	1.047 g/mL at 25 °C(lit.)
refractive index	n20/D 1.444(lit.)
Flash point	183 °F
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Chloroform, Methanol
pka	pK1:4.785 (25°C)
form	Liquid
color	Clear colorless to yellow
Specific Gravity	1.047
Water Solubility	Slightly soluble in water.
BRN	1816777
InChI	1S/C5H8O2/c6-5(7)4-2-1-3-4/h4H,1-3H2,(H,6,7)
InChIKey	TXWOGHSRPAYOML-UHFFFAOYSA-N
SMILES	OC(=O)C1CCC1
CAS DataBase Reference	3721-95-7(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	0RDJ7C51O0
NIST Chemistry Reference	Cyclobutane carboxylic acid(3721-95-7)
EPA Substance Registry System	Cyclobutanecarboxylic acid (3721-95-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338

PPE

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Codes

Xi,C

Risk Statements

36/37/38-34-20/21/22

Safety Statements

23-24/25-36-26-45-36/37/39

RIDADR

3265

WGK Germany

RTECS

GU1335000

TSCA

TSCA listed

HazardClass

PackingGroup

III

HS Code

29162000

Storage Class

8A - Combustible corrosive hazardous materials

Hazard Classifications

Skin Corr. 1B

Limited Quantities

5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	2
2		0

Cyclobutanecarboxylic acid price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	C95609	Cyclobutanecarboxylic acid 98%	3721-95-7	5g	$38.66	2025-07-31	Buy
Sigma-Aldrich	C95609	Cyclobutanecarboxylic acid 98%	3721-95-7	25g	$75.5	2025-07-31	Buy
TCI Chemical	C0888	Cyclobutanecarboxylic Acid >97.0%(GC)(T)	3721-95-7	10g	$35	2025-07-31	Buy
TCI Chemical	C0888	Cyclobutanecarboxylic Acid >97.0%(GC)(T)	3721-95-7	25g	$67	2025-07-31	Buy
Sigma-Aldrich	C95609	Cyclobutanecarboxylic acid 98%	3721-95-7	100g	$205	2025-07-31	Buy

Product number	Packaging	Price	Buy
C95609	5g	$38.66	Buy
C95609	25g	$75.5	Buy
C0888	10g	$35	Buy
C0888	25g	$67	Buy
C95609	100g	$205	Buy

Cyclobutanecarboxylic acid Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS TO SLIGHTLY AMBER LIQUID

Uses

Cyclobutanecarboxylic acid is used in water treatment, row materials for sodium fluosilicate potassium fluosilicateammonium fluosilicatecopper fluosilicatebarium fluosilicate and other fluosilicates and silicic tetrafluoride. It is also used in refining lead of electrolysis, as mordant and in the treatment of metal surface.

Preparation

Cyclobutanecarboxylic acid synthesis: Put 1,1-Cyclobutanedicarboxylic acid into a distillation device for heating, decarboxylate at about 160°C to release carbon dioxide, then heat for distillation, collect 189-195°C fractions as crude product, and re-distill to obtain the finished product cyclobutanecarboxylic acid. Yield 86%-91%.

Synthesis Reference(s)

The Journal of Organic Chemistry, 22, p. 1680, 1957 DOI: 10.1021/jo01363a041

Purification Methods

Dissolve the acid in aqueous HCO 3 then acidify with HCl and extract it into Et2O, wash with H2O, dry (Na2SO4), concentrate to a small volume, then distil it through a glass helices packed column. The S-benzylisothiuronium salt has m 176o (from EtOH), the anilide has m 112.5-113o, and the p-toluide has m 123o. [Payne & Smith J Org Chem 22 1680 1957, Kantaro & Gunning J Am Chem Soc 73 480 1951, Stodola & Heisig Org Synth Coll Vol III 213 1955, Beilstein 9 H 5.]

Cyclobutanecarboxylic acid synthesis

Synthesis of Cyclobutanecarboxylic acid from Ethylene and Acrylic acid

Cyclobutanecarboxylic acid Preparation Products And Raw materials

Raw materials

1,1-Cyclobutanedicarboxylic acid 3-Iodo-cyclobutanecarboxylic acid ethyl ester CYCLOBUTYL-ACETIC ACID Ethyl cyclobutanecarboxylate Diethyl 1,1-cyclobutanedicarboxylate

Preparation Products

Cyclobutanemethanol (Bromomethyl)cyclobutane Cyclobutanecarbonyl chloride Cyclobutanecarboxaldehyde delta-Valerolactone

Cyclobutanecarboxylic acid, 1-(trimethylsilyl)- CYCLOBUTANE-1,1-DICARBOXYLIC ACID ETHYL ESTER Cyclobutyl chloride Cyclobutanecarbonitrile tert-butyl cyclobutanecarboxylate

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Cyclobutanecarboxylic acid Suppliers

Global( 513)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	1006	58
Zhejiang Karry Pharmachem Co., Ltd.	+8613567161161	info@karrypharma.com	China	34	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20128	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13676	58
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21597	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58

Supplier	Advantage
Hangzhou ICH Biofarm Co., Ltd	58
Zhejiang Karry Pharmachem Co., Ltd.	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58

Cyclobutanecarboxylic Acid in Organic chemistry
Cyclobutanecarboxylic acid, enables enantioselective C–H activation for chiral cyclobutanes and serves as a scaffold for αvβ3 ....
Jan 27，2026

View Lastest Price from Cyclobutanecarboxylic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-01-04	Cyclobutanecarboxylic acid 3721-95-7	US $0.00-0.00 / kg	0.10000000149011612kg	99.0%min	5MT	Hangzhou ICH Biofarm Co., Ltd
2025-09-25	Cyclo-butyl formic acid 3721-95-7	US $5.00-0.50 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2025-06-27	Cyclobutanecarboxylic acid 3721-95-7	US $30.00-10.00 / KG	50KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd

Cyclobutanecarboxylic acid
3721-95-7
US $0.00-0.00 / kg
99.0%min
Hangzhou ICH Biofarm Co., Ltd

Cyclo-butyl formic acid
3721-95-7
US $5.00-0.50 / KG
99%
Henan Fengda Chemical Co., Ltd

Cyclobutanecarboxylic acid
3721-95-7
US $30.00-10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Cyclobutanecarboxylic acid Spectrum

Cyclobutanecarboxylic acid(3721-95-7)MS Cyclobutanecarboxylic acid(3721-95-7)¹HNMR Cyclobutanecarboxylic acid(3721-95-7)¹³CNMR Cyclobutanecarboxylic acid(3721-95-7)IR1 Cyclobutanecarboxylic acid(3721-95-7)Raman

3721-95-7(Cyclobutanecarboxylic acid)Related Search:

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Cyclopropanecarboxylic acid Retinoic acid Benzoic acid Tetrabutylammonium bromide Citric acid

Methyl perfluoroisobutyl ether Glycine Diethyl 1,1-cyclobutanedicarboxylate

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RARECHEM AL BO 0291 CYCLO-BUTYL FORMIC ACID Cyclobutylcarboxylic acid cyclobutylcarboxylicacid Cyclobutanecarbonyl acid cyclobutane carboyxlic acid CYCLOBUTANOIC ACID 98% (GC) CYCLOBUTANECARBOXYLIC AICD CyclobutanecarboxylicAcid98% cyclobutancecarboxylic acid Cyclobutyl carboxilic acid Cyclo-butyl formic a Cyclobutane-1-carboxylic acid cyclobutanecarboxylate obutanecarboxyL Cyclobutanecarboxylic acid, 98% 25GR Ring butyl forMate Cyclobutane carbonic acid Cyclobutanecarboxylic acid 98% Cyclobutanecarboxylic Acid > Cyclobutanecarboxylic acid, 98%, for synthesis Cyclobutancarbonsure TIANFUCHEM-- 3721-95-7-- Cyclobutanecarboxylic acid in stock CYCLOBUTANECARBOXYLIC ACID Cyclobutanecarboxylic acid (6CI, 7CI, 8CI, 9CI, ACI) Adipic acid impurity5（Cyclobutanecarboxylic acid） Cyclobutanecaboxylic acid 3721-95-7 3271-95-7 3721-95-8 C4H7COOH C4H7CO2H CARBOXYLIC ACID Organic Building Blocks C1 to C5 Carbonyl Compounds Carboxylic Acids Building Blocks Simple 4-Membered Ring Compounds Cyclobutanes & Cyclobutenes Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Acids and Derivatives Cyclobutanes & Cyclobutenes Simple 4-Membered Ring Compounds Cycloalkanes C1 to C5 Carbonyl Compounds Carboxylic Acids bc0001