Diethoxyacetonitrile
- CAS No.
- 6136-93-2
- Chemical Name:
- Diethoxyacetonitrile
- Synonyms
- Einecs 228-111-1;diethoxy-acetonitril;DIETHOXYACETONITRILE;Acetonitrile, diethoxy-;2,2-diethoxyacetonitrile;1,1-Diethoxyacetonitrile;Acetonitrile, 2,2-diethoxy-;2,2-Diethoxyacetonitrile,98%;DIETHOXYACETONITRILE ISO 9001：2015 REACH;China biggest manufacturer DIETHOXYACETONITRILE 6136-93-2
- CBNumber:
- CB5136964
- Molecular Formula:
- C6H11NO2
- Molecular Weight:
- 129.16
- MDL Number:
- MFCD00043982
- MOL File:
- 6136-93-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Diethoxyacetonitrile 97% | 370460 | 5g | $49.1 |
| Diethoxyacetonitrile 97% | 370460 | 25g | $97.5 |
| Diethoxyacetonitrile | 086027 | 100.00g | $63 |
| Diethoxyacetonitrile | 086027 | 500.00g | $225 |
| 2,2-Diethoxyacetonitrile 97% | D41500 | 1g | $25 |
| More product size | |||
| Melting point | -19--18 °C (lit.) |
|---|---|
| Boiling point | 167.7 °C/773 mmHg (lit.) |
| Density | 0.929 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 121 °F |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | liquid |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C6H11NO2/c1-3-8-6(5-7)9-4-2/h6H,3-4H2,1-2H3 |
| InChIKey | UDELMRIGXNCYLU-UHFFFAOYSA-N |
| SMILES | C(#N)C(OCC)OCC |
| EPA Substance Registry System | Acetonitrile, diethoxy- (6136-93-2) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H302+H312+H332 | |||||||||
| Precautionary statements | P210-P280-P301+P312+P330-P302+P352+P312-P304+P340+P312 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 10-20/21/22-36/37/38 | |||||||||
| Safety Statements | 16-26-27-36/37/39 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3.2 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2926907090 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Flam. Liq. 3 |
|||||||||
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
Diethoxyacetonitrile price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 370460 | Diethoxyacetonitrile 97% | 6136-93-2 | 5g | $49.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 370460 | Diethoxyacetonitrile 97% | 6136-93-2 | 25g | $97.5 | 2026-04-30 | Buy |
| Matrix Scientific | 086027 | Diethoxyacetonitrile | 6136-93-2 | 100.00g | $63 | 2026-05-18 | Buy |
| Matrix Scientific | 086027 | Diethoxyacetonitrile | 6136-93-2 | 500.00g | $225 | 2026-05-18 | Buy |
| Synthonix | D41500 | 2,2-Diethoxyacetonitrile 97% | 6136-93-2 | 1g | $25 | 2026-05-06 | Buy |
Diethoxyacetonitrile Chemical Properties,Uses,Production
Uses
Diethoxyacetonitrile may be used in the preparation of methyl 5-diethoxymethylimidazole-4-carboxylate, via anionic cycloaddition reaction with methyl isocyanoacetate.
General Description
Diethoxyacetonitrile is a 2,2-dialkoxyalkanenitrile derivative. Reaction of hydrocyanic acid with various ortho esters of aliphatic and aromatic acids in the presence of acidic catalyst has been reported to afford diethoxyacetonitrile. Houben-Hoesch reaction of diethoxyacetonitrile with 1,2,4-trimethoxybenzene affords tris(2,4,5-trimethoxyphenyl)methane.
Synthesis
61189-99-9
6136-93-2
The general procedure for the synthesis of diethoxyacetonitrile from 2,2-diethoxyacetamide is as follows (cf. Inami, K., Shiba, T., Bull. Chem. Soc. Jpn., 1985, 58, 352): 2,2-diethoxyacetamide (7.13 g, 49.04 mmol) was dissolved in toluene (50 mL), followed by the addition of triethylamine (NEt3, 10.4 mL) and phosphorus pentoxide (P2O5, 9.04 g, 64.32 mmol). The reaction mixture was stirred for 1 hour. Upon completion of the reaction, the solvent was first removed by distillation at atmospheric pressure and then changed to reduced pressure distillation to collect the diethoxyacetonitrile to give a clear, colorless liquid product (4.049 g, 64% yield). The boiling point of the product was 100 °C (12-15 mmHg). IR spectra (KBr, cm^-1): 2983, 2937, 2896 (υC-H), 2247 (υC≡N), 1067 (δC-O). NMR hydrogen spectrum (CDCl3): δ 1.27 (6H, t, J = 8.0 Hz, 2 × CH3), 3.73 (4H, m, 2 × CH2), 5.31 (1H, s, CH). Low Resolution Mass Spectrometry (LREIMS): measured value 130.13 (M+H), calculated value C6H11NO2 129.08.
References
[1] Bulletin of the Chemical Society of Japan, 1985, vol. 58, # 1, p. 352 - 360
[2] Patent: WO2008/38018, 2008, A1. Location in patent: Page/Page column 63-64
[3] Journal of the American Chemical Society, 1947, vol. 69, p. 2660
[4] Chemische Berichte, 1934, vol. 67, p. 1507,1511
Diethoxyacetonitrile Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5233 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 18895 | 58 |
View Lastest Price from Diethoxyacetonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-01 | Diethoxyacetonitrile
6136-93-2
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2025-05-26 | DIETHOXYACETONITRILE
6136-93-2
|
US $10.00 / KG | 1KG | 99.% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2024-04-25 | DIETHOXYACETONITRILE
6136-93-2
|
US $10.00 / kg | 1kg | 99.6% | 100000 | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- Diethoxyacetonitrile
6136-93-2
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- DIETHOXYACETONITRILE
6136-93-2
- US $10.00 / KG
- 99.%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- DIETHOXYACETONITRILE
6136-93-2
- US $10.00 / kg
- 99.6%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
6136-93-2(Diethoxyacetonitrile)Related Search:
1of3
