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ChemicalBook >> CAS DataBase List >>5-METHYL-2H-ISOQUINOLIN-1-ONE

5-METHYL-2H-ISOQUINOLIN-1-ONE

5-METHYL-2H-ISOQUINOLIN-1-ONE Structure
5-METHYL-2H-ISOQUINOLIN-1-ONE structure
CAS No.
24188-72-5
Chemical Name:
5-METHYL-2H-ISOQUINOLIN-1-ONE
Synonyms
5-Methylisoquinolin-1-ol;5-Methylisoquinolin-1(2H);5-METHYL-2H-ISOQUINOLIN-1-ONE;5-methylisoquinolin-1(2H)-one;5-methyl-1(2H)-isoquinolinone;5-Methyl-2H-Isoquinoline-1-one;1(2H)-Isoquinolinone, 5-methyl-;5-methyl-1,2-dihydroisoquinolin-1-one
CBNumber:
CB5142505
Molecular Formula:
C10H9NO
Molecular Weight:
159.18
MDL Number:
MFCD07357397
MOL File:
24188-72-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:46
Product description Number Pack Size Price
5-Methylisoquinolin-1-ol Y5357 250mg $154
5-METHYL-2H-ISOQUINOLIN-1-ONE 95.00% CHM0376350 5MG $497.89
5-methylisoquinolin-1(2H)-one 97% CM143617 5g $539
5-Methylisoquinolin-1(2H)-one 97% CD11160276 5g $570
5-methylisoquinolin-1(2H)-one 97% CM143617 10g $970
Request For Quotation

5-METHYL-2H-ISOQUINOLIN-1-ONE Properties

Boiling point 400.5±45.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 13.12±0.20(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

5-METHYL-2H-ISOQUINOLIN-1-ONE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific Y5357 5-Methylisoquinolin-1-ol 24188-72-5 250mg $154 2021-12-16 Buy
American Custom Chemicals Corporation CHM0376350 5-METHYL-2H-ISOQUINOLIN-1-ONE 95.00% 24188-72-5 5MG $497.89 2021-12-16 Buy
Chemenu CM143617 5-methylisoquinolin-1(2H)-one 97% 24188-72-5 5g $539 2021-12-16 Buy
Crysdot CD11160276 5-Methylisoquinolin-1(2H)-one 97% 24188-72-5 5g $570 2021-12-16 Buy
Chemenu CM143617 5-methylisoquinolin-1(2H)-one 97% 24188-72-5 10g $970 2021-12-16 Buy
Product number Packaging Price Buy
Y5357 250mg $154 Buy
CHM0376350 5MG $497.89 Buy
CM143617 5g $539 Buy
CD11160276 5g $570 Buy
CM143617 10g $970 Buy

5-METHYL-2H-ISOQUINOLIN-1-ONE Chemical Properties,Uses,Production

Synthesis

2-Propenoyl azide, 3-(2-methylphenyl)-, (2E)-

872509-52-9

5-METHYL-2H-ISOQUINOLIN-1-ONE

24188-72-5

Synthesis of Intermediate-3: 5-Methylisoquinolin-1(2H)-one: o-Methylcinnamoyl azide (Intermediate-2) (10 g, 53.5 mmol) was dissolved in toluene (100 mL) with stirring and heated to 110±2°C for 1 hour. After completion of the reaction, the toluene solvent was removed under reduced pressure, 1,2-dichlorobenzene (DCB) (100 mL) and iodine (catalytic amount) were added, and the reaction mixture was heated to 180±2°C and kept reacting overnight. At the end of the reaction, the solvent was removed under reduced pressure and the product was purified by recrystallization (ethyl acetate: hexane = 90:10) to afford the target compound 5-methylisoquinolin-1(2H)-one (4 g, 45% yield).

References

[1] Patent: US2013/178457, 2013, A1. Location in patent: Paragraph 0175
[2] Patent: WO2013/5168, 2013, A2. Location in patent: Page/Page column 33
[3] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 8, p. 1147 - 1156
[4] Journal of Heterocyclic Chemistry, 2001, vol. 38, # 4, p. 961 - 964

5-METHYL-2H-ISOQUINOLIN-1-ONE synthesis

131002-06-7
24188-72-5
Synthesis of 5-METHYL-2H-ISOQUINOLIN-1-ONE from Benzamide, 2-ethenyl-3-methyl- (9CI)

5-METHYL-2H-ISOQUINOLIN-1-ONE Preparation Products And Raw materials

Raw materials

2-Propenoyl azide, 3-(2-methylphenyl)-, (2E)- 1,2-Dichlorobenzene Toluene iodine

Preparation Products

5-METHYL-2H-ISOQUINOLIN-1-ONE Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Nanjing jinheyou Trading Co., Ltd. 		15705188088 admin@jheyou.com CHINA 1268 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
ZEROSCHEM.CO.,LTD. 10-61256048 13810278579 sales@zeroschem.com China 1360 59
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4267 65
SynAsst Chemical. 021-60343070 China 12740 55
Bide Pharmatech Ltd. 400-164-7117 13681763483 product02@bidepharm.com China 42446 60
ShangHai AmK Pharmaceutical Technology Co., Ltd. 18019252918 sale@amkchem.com China 15197 55
Supplier Advantage
Alchem Pharmtech,Inc. 		58
Nanjing jinheyou Trading Co., Ltd. 		58
career henan chemical co 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
ZEROSCHEM.CO.,LTD. 59
Shanghai Ennopharm Co., Ltd. 65
SynAsst Chemical. 55
Bide Pharmatech Ltd. 60
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55

View Lastest Price from 5-METHYL-2H-ISOQUINOLIN-1-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-METHYL-2H-ISOQUINOLIN-1-ONE pictures 2020-01-15 5-METHYL-2H-ISOQUINOLIN-1-ONE
24188-72-5
 US $5.50 / KG 1KG 98%min 1kg-100kg Career Henan Chemical Co
5-METHYL-2H-ISOQUINOLIN-1-ONE pictures 2019-12-20 5-METHYL-2H-ISOQUINOLIN-1-ONE
24188-72-5
 US $0.00 / g 1g 95%min 20kg/month Nanjing jinheyou Trading Co., Ltd.

5-METHYL-2H-ISOQUINOLIN-1-ONE Spectrum

5-METHYL-2H-ISOQUINOLIN-1-ONE(24188-72-5)1HNMR

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5-METHYL-2H-ISOQUINOLIN-1-ONE 5-Methylisoquinolin-1(2H) 5-methyl-1,2-dihydroisoquinolin-1-one 5-methylisoquinolin-1(2H)-one 5-Methyl-2H-Isoquinoline-1-one 5-Methylisoquinolin-1-ol 5-methyl-1(2H)-isoquinolinone 1(2H)-Isoquinolinone, 5-methyl- 24188-72-5