5-amino-1,2-dihydropyrazol-3-one
- CAS No.
- 28491-52-3
- Chemical Name:
- 5-amino-1,2-dihydropyrazol-3-one
- Synonyms
- 5-amino-1,2-dihydro-3H-pyrazol-3-one;-5-one;5-Amino-1H-pyrazol-3(2H);3-Amino-3-pyrazolin-5-one;3-Amino-1,2-dihydropyrazoL;5-AMino-1H-pyrazol-3(2H)-one;5-Amino-3-hydroxy-1H-pyrazole;3-Amino-1,2-dihydropyrazol-5-one;5-amino-1,2-dihydropyrazol-3-one;3H-Pyrazol-3-one,5-amino-1,2-dihydro-
- CBNumber:
- CB51463409
- Molecular Formula:
- C3H5N3O
- Molecular Weight:
- 99.09
- MDL Number:
- MFCD00204482
- MOL File:
- 28491-52-3.mol
- MSDS File:
- SDS
| Melting point | 204℃ |
|---|---|
| Density | 1.301 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 8.31±0.70(Predicted) |
| Appearance | Light brown to brown Solid |
| InChI | InChI=1S/C3H5N3O/c4-2-1-3(7)6-5-2/h1H,(H4,4,5,6,7) |
| InChIKey | QZBGOTVBHYKUDS-UHFFFAOYSA-N |
| SMILES | N1C(N)=CC(=O)N1 |
5-amino-1,2-dihydropyrazol-3-one price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS34074 | 3-Amino-1,2-dihydropyrazol-5-one 98% | 28491-52-3 | 5g | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS34074 | 3-Amino-1,2-dihydropyrazol-5-one 98% | 28491-52-3 | 25g | $73 | 2026-06-04 | Buy |
| Activate Scientific | AS34074 | 3-Amino-1,2-dihydropyrazol-5-one 98% | 28491-52-3 | 100g | $219 | 2026-06-04 | Buy |
| Synthonix | A0899 | 5-Amino-1,2-dihydropyrazol-3-one 97% | 28491-52-3 | 1g | $15 | 2026-05-06 | Buy |
| Synthonix | A0899 | 5-Amino-1,2-dihydropyrazol-3-one 97% | 28491-52-3 | 5g | $23 | 2026-05-06 | Buy |
5-amino-1,2-dihydropyrazol-3-one Chemical Properties, Uses, Production
Synthesis
37832-55-6
28491-52-3
General procedure for the synthesis of 5-amino-1H-pyrazol-3-one from 5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid: to a reaction flask was added toluene (500 mL), triethylamine (138.6 mL, 1.0 mol, 2.0 eq), and 5-hydroxy-4-carboxylic acid ester (64 g, 0.5 mol, 1.0 eq) made in step (1). After raising the temperature of the reaction system to 80°C, diphenylphosphoryl azide (DPPA, 162.5 mL, 0.75 mol, 1.5 eq) was slowly added and stirred continuously for 5 hours at this temperature. After the reaction was completed, the system was cooled to room temperature. The reaction solution was concentrated, 500 mL of saturated aqueous ammonium chloride solution was added, the precipitated white precipitate was collected and dried to give 5-amino-1,2-dihydro-pyrazol-3-one 44.7 g in 90% yield.
References
[1] Patent: CN105541719, 2016, A. Location in patent: Paragraph 0028; 0030
5-amino-1,2-dihydropyrazol-3-one Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Mailekang Pharmaceutical Technology Co., Ltd. | 0519-69655553 13961137915 | mlksales@126.com | China | 62 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| Dancheng Huatai Biotechnology Co., Ltd. | 13482210809 13482210809 | hli@3wpharm.com | China | 357 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Acorn PharmaTech Co., Ltd. | 025-58395930 | sales@acornpharma.com | China | 982 | 60 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
View Latest Price from 5-amino-1,2-dihydropyrazol-3-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | 5-amino-1,2-dihydropyrazol-3-one
28491-52-3
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2022-01-15 | 3-Amino-1,2-dihydropyrazol-5-one
28491-52-3
|
1KG | 99.5% | 100 tons | Honest Joy Holdings Limited | ||
 |
2019-07-06 | 5-amino-1,2-dihydropyrazol-3-one
28491-52-3
|
$1.00 | 1KG | 96% | 500kg | Career Henan Chemical Co |
-
- 5-amino-1,2-dihydropyrazol-3-one
28491-52-3
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 3-Amino-1,2-dihydropyrazol-5-one
28491-52-3
- $0.00
- 99.5%
- Honest Joy Holdings Limited
-
- 5-amino-1,2-dihydropyrazol-3-one
28491-52-3
- $1.00
- 96%
- Career Henan Chemical Co
