Methane sulfonyl azide
- CAS No.
- 1516-70-7
- Chemical Name:
- Methane sulfonyl azide
- Synonyms
- Methylsulfonyl azide;Methane sulfonyl azide;METHANE SULPHONYLAZIDE;N-diazomethanesulfonamide;Methanesulfonic acid azide;Methane Sulphonyl Azide-Bulk
- CBNumber:
- CB51466147
- Molecular Formula:
- CH3N3O2S
- Molecular Weight:
- 0
- MDL Number:
- MFCD17013585
- MOL File:
- 1516-70-7.mol
- MSDS File:
- SDS
| Melting point | 91-92 °C |
|---|---|
| Boiling point | 59-60 °C(Press: 17 Torr) |
| Density | 1.4361 g/cm3 |
| refractive index | 1.4675 |
| solubility | sol Et2O, MeOH, MeCN; sparingly sol 95% EtOH, cold H2O. |
| Appearance | low-melting white solid or clear, colorless oil |
| InChI | InChI=1S/CH3N3O2S/c1-7(5,6)4-3-2/h1H3 |
| InChIKey | BHQIGUWUNPQBJY-UHFFFAOYSA-N |
| SMILES | CS(N=[N+]=[N-])(=O)=O |
Methane sulfonyl azide Chemical Properties,Uses,Production
Uses
Methane sulfonyl azide is used as a diazo transfer reagent for activated methylene,[1] methine,[1,2] and methyl[3] groups; functionalization of double and triple bonds.
Preparation
Preparative Methods of Methane sulfonyl azide: reaction of Methanesulfonyl Chloride with Sodium Azide in MeOH(EtOH)/H2O[1,3] or acetone[2] (55-61 or 96% yields, respectively). By substituting acetone for methanol, the formation of MeSO2OMe is avoided and the reagent is obtained in >95% purity.
storage
Methane sulfonyl azide should be stored in the cold and the dark. Explosive when heated above 130 °C. No experimentalists have reported any difficulty handling MsN3, but proper caution should be used, as with all azide reagents. Use in a fume hood.
Purification Methods
Purification of Methane sulfonyl azide: crystallization from ether in dry-ice/acetone or from 95% EtOH at -75 °C; distillation in vacuo.
References
1. (a) Taber, D. F.; Ruckle, R. E.; Hennessy, M. J. JOC 1986, 51, 4077. (b) Taber, D. F.; Hennessy, M. J.; Lovey, J. P.
JOC 1992, 57, 436.
2. Danheiser, R. L.; Miller, R. F.; Brisbois, R. G.; Park, S. Z. JOC 1990, 55, 1959.
3. Shatzmiller, S.; Bercovici, S. LA 1992, 877.
Methane sulfonyl azide Preparation Products And Raw materials
Methane sulfonyl azide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21597 | 55 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618791163155 | 18791163155@163.com | China | 3397 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| chengqiaotech.ltd | 18105338618 | zbcqyh@126.com | China | 296 | 58 |
| Wuhan Yingnuo Pharmaceutical Technology Co., Ltd. | 15387063101 | 2881924050@qq.com | China | 9997 | 58 |
| Shaanxi Gulliver Biotechnology Research Co., Ltd | 0917-77953337 18409274651 | 2823986536@qq.com | China | 3395 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12740 | 55 | |
| Changzhou Hopschain Chemical Co.,Ltd. | 0519-85528066 13775048983 | sales@hopschem.com | China | 31553 | 55 |
View Lastest Price from Methane sulfonyl azide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-03 | Methane sulfonyl azide
1516-70-7
|
US $85.00-850.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd |
-
- Methane sulfonyl azide
1516-70-7
- US $85.00-850.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
