Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt)
- Synonyms
- Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt)
- CBNumber:
- CB515488254
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 37409 | Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt) ≥90% | 1mg | $478 | 2026-04-30 | Buy | |
| Cayman Chemical | 37409 | Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt) ≥90% | 5mg | $1789 | 2026-04-30 | Buy | |
| Cayman Chemical | 37409 | Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt) ≥90% | 10mg | $3339 | 2026-04-30 | Buy |
Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
Dabcyl-K-SARS-CoV-2 replicase polyprotein 1ab (pp1ab) (3235-3246)-E-EDANS is a fluorogenic substrate for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro).1,2 Upon enzymatic cleavage by SARS-CoV or SARS-CoV-2 Mpro at the Gln-Ser site, EDANS is separated from the Dabcyl quencher and its fluorescence can be used to quantify SARS-CoV or SARS-CoV-2 Mpro activity.1,2,3 EDANS displays excitation/emission maxima of 340/485 nm, respectively.WARNING This product is not for human or veterinary use.
References
[1] JOHN T.-A. HSU. Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV[J]. FEBS Letters, 2004, 574 1-3: 116-120. DOI: 10.1016/j.febslet.2004.08.015
[2] TING XIAO . Effect of dihydromyricetin on SARS-CoV-2 viral replication and pulmonary inflammation and fibrosis[J]. Phytomedicine, 2021, 91: Article 153704. DOI: 10.1016/j.phymed.2021.153704
[3] YUNJEONG KIM. Broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.[J]. Journal of Virology, 2012, 86 21: 11754-11762. DOI: 10.1128/jvi.01348-12
Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6808 | 58 |
| Neobioscience Co., Ltd. | -- | info@neobioscience.com | CHINA | 6192 | 58 |
| Supplier | Advantage |
|---|---|
| Cayman Chemical Company | 58 |
| Neobioscience Co., Ltd. | 58 |
