6-Aminoindazole
- CAS No.
- 6967-12-0
- Chemical Name:
- 6-Aminoindazole
- Synonyms
- 1h-indazol-6-amine;6-AMINO-1H-INDAZOLE;Aminoidazole;Aminoindazole;6-Aminoidazole;6-Indazolamine;6-AMINOINDAZOLE;indazol-6-ylamine;AKOS BBS-00003578;6-AMinoindazole 98%
- CBNumber:
- CB5174982
- Molecular Formula:
- C7H7N3
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD00005696
- MOL File:
- 6967-12-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-Aminoindazole >98.0%(HPLC)(T) | A0798 | 25g | $80 |
| 6-Aminoindazole Asreported | 260172 | 5g | $319 |
| 6-Aminoindazole Asreported | 260172 | 10g | $432 |
| 6-Aminoindazole Asreported | 260172 | 25g | $602 |
| 6-Aminoindazole Asreported | 260172 | 50g | $782 |
| More product size | |||
| Melting point | 204-206 °C (dec.) (lit.) |
|---|---|
| Boiling point | 376.6±15.0 °C(Predicted) |
| Density | 1.367±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 15.61±0.40(Predicted) |
| form | Powder |
| color | Tan |
| InChI | InChI=1S/C7H7N3/c8-6-2-1-5-4-9-10-7(5)3-6/h1-4H,8H2,(H,9,10) |
| InChIKey | KEJFADGISRFLFO-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC(N)=C2)C=N1 |
| CAS DataBase Reference | 6967-12-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | KN72RH56SR |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NK7712000 | |||||||||
| HS Code | 29339980 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
6-Aminoindazole price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A0798 | 6-Aminoindazole >98.0%(HPLC)(T) | 6967-12-0 | 25g | $80 | 2026-04-30 | Buy |
| Usbiological | 260172 | 6-Aminoindazole Asreported | 6967-12-0 | 5g | $319 | 2026-06-03 | Buy |
| Usbiological | 260172 | 6-Aminoindazole Asreported | 6967-12-0 | 10g | $432 | 2026-06-03 | Buy |
| Usbiological | 260172 | 6-Aminoindazole Asreported | 6967-12-0 | 25g | $602 | 2026-06-03 | Buy |
| Usbiological | 260172 | 6-Aminoindazole Asreported | 6967-12-0 | 50g | $782 | 2026-06-03 | Buy |
6-Aminoindazole Chemical Properties,Uses,Production
Description
6-Aminoindazole is a tetronic acid derivative that has been shown to have an inhibitory effect on the activity of cyclopentyl and ethylene diamine. This drug also increases blood pressure in animals, and is found to be a potent inhibitor of thrombin receptor.
Chemical Properties
light brown powder
Application
6-Aminoindazole is structurally similar to quinoline derivatives and has been shown to have anticancer activity in human ovarian carcinoma cells. The affinity constants for this compound are higher than those for most other compounds with anti-cancer effects, which may be due to the presence of hydrogen bonds between the nitrogen atoms and the carbonyl group.
Definition
ChEBI: 1H-indazol-6-amine is a member of indazoles.
Synthesis
7597-18-4
6967-12-0
General procedure for the synthesis of 6-aminoindazole from 6-nitro-1H-indazole: 6-nitro-1H-indazole (25 g, 0.153 mol, commercially available) was mixed with 10% Pd/C catalyst (2.0 g) in methanol, and the reaction was stirred overnight under hydrogen atmosphere (1 atm). After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford 6-amino-1H-indazole (18.5 g, 94% yield) as a yellow solid.
Purification Methods
It is recrystallised from H2O or EtOH and sublimes in a vacuum. [Beilstein 25 H 317.]
References
[1] Tetrahedron Letters, 2010, vol. 51, # 5, p. 786 - 789
[2] ChemCatChem, 2014, vol. 6, # 11, p. 3153 - 3159
[3] Tetrahedron, 2008, vol. 64, # 28, p. 6711 - 6723
[4] Patent: WO2006/71940, 2006, A2. Location in patent: Page/Page column 407
[5] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 11, p. 3177 - 3180
6-Aminoindazole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Zison Pharmaceutical (Shandong) Co., Ltd. | +86-0086-531-88259693 +86-18660188356 | tracy.li@zisonpharm.com | China | 88 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 9542 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from 6-Aminoindazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-15 | 6-amino-1H-indazole
6967-12-0
|
1kg | ≥98% by HPLC | 100kg/month | Zison Pharmaceutical (Shandong) Co., Ltd. | ||
 |
2025-04-04 | 6-Aminoindazole
6967-12-0
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2021-07-13 | 6-Aminoindazole
6967-12-0
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 6-amino-1H-indazole
6967-12-0
- ≥98% by HPLC
- Zison Pharmaceutical (Shandong) Co., Ltd.
-
- 6-Aminoindazole
6967-12-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 6-Aminoindazole
6967-12-0
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
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