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L-Lysine hydrochloride

CAS No.
657-27-2
Chemical Name:
L-Lysine hydrochloride
Synonyms
L-LYSINE HCL;L-LYSINE MONOHYDROCHLORIDE;LYSINE HCL;LYSINE HYDROCHLORIDE;LYSINE MONOHYDROCHLORIDE;L-Lysine HCl USP;monohydrochloride,l-lysin;Lysine Hydrochloride, Powder;L-LYS HCL;L-LYSINE HYDROCHLORIDE USP
CBNumber:
CB5180129
Molecular Formula:
C6H14N2O2.ClH
Molecular Weight:
182.65
MDL Number:
MFCD00064564
MOL File:
657-27-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-30 08:01:27
Product description Number Pack Size Price
(S)-(+)-Lysine monohydrochloride for synthesis 8.16018 100g $57.7
Lysine hydrochloride European Pharmacopoeia (EP) Reference Standard L0900000 50 mg $254
(S)-(+)-Lysine monohydrochloride for synthesis 8.16018 500g $166
L-Lysine, Hydrochloride An essential amino acid. 4400-M 100g $71.4
L-Lysine monohydrochloride BioUltra, ≥99.5% (AT) 62929 100g $77.8
More product size

L-Lysine hydrochloride Properties

Melting point 263 °C (dec.)(lit.)
alpha 21 º (c=8, 6N HCl)
Density 1.28 g/cm3 (20℃)
bulk density 360kg/m3
vapor pressure <1 Pa (20 °C)
FEMA 3847 | L-LYSINE
FLAVIS Number 17.031 | L-(+)-Lysine monohydrochloride
storage temp. 2-8°C
solubility H2O: 100 mg/mL
form powder
color White to Off-white
Odor odorless
PH 5.5-6.0 (100g/l, H2O, 20℃)
biological source non-animal source
optical activity [α]20/D +20.5±0.5°, c = 5% in 5 M HCl
Water Solubility 65 g/100 mL (20 ºC)
λmax λ: 260 nm Amax: 0.1
λ: 280 nm Amax: 0.1
Merck 14,5636
BRN 3563889
Stability Stable. Incompatible with strong oxidizing agents.
Major Application pharmaceutical (small molecule)
Cosmetics Ingredients Functions HAIR CONDITIONING
SKIN CONDITIONING
Cosmetic Ingredient Review (CIR) L-Lysine hydrochloride (657-27-2)
InChI 1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1
InChIKey BVHLGVCQOALMSV-JEDNCBNOSA-N
SMILES OC([C@@H](N)CCCCN)=O.[H]Cl
LogP -1.036 (est)
CAS DataBase Reference 657-27-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII JNJ23Q2COM
EPA Substance Registry System Lysine hydrochloride (657-27-2)
UNSPSC Code 41116107
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261-P271
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes 
WGK Germany  2
RTECS  OL5650000
TSCA  TSCA listed
HS Code  2922410000
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
1
1 0

L-Lysine hydrochloride price More Price(126)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.16018 (S)-(+)-Lysine monohydrochloride for synthesis 657-27-2 100g $57.7 2026-04-30 Buy
Sigma-Aldrich L0900000 Lysine hydrochloride European Pharmacopoeia (EP) Reference Standard 657-27-2 50 mg $254 2026-04-30 Buy
Sigma-Aldrich 8.16018 (S)-(+)-Lysine monohydrochloride for synthesis 657-27-2 500g $166 2026-04-30 Buy
Sigma-Aldrich 4400-M L-Lysine, Hydrochloride An essential amino acid. 657-27-2 100g $71.4 2026-04-30 Buy
Sigma-Aldrich 62929 L-Lysine monohydrochloride BioUltra, ≥99.5% (AT) 657-27-2 100g $77.8 2026-04-30 Buy
Product number Packaging Price Buy
8.16018 100g $57.7 Buy
L0900000 50 mg $254 Buy
8.16018 500g $166 Buy
4400-M 100g $71.4 Buy
62929 100g $77.8 Buy

L-Lysine hydrochloride Chemical Properties,Uses,Production

Synthesis

L-Lysine hydrochloride can be synthesisied by microbial fermentation to give crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.

Description

L-Lysine hydrochloride is a white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble in alcohol and in ether. It melts at about 260°C with decomposition.

Chemical Properties

White crystalline powder

Uses

L-Lysine hydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine. It can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.

Definition

ChEBI: The hydrochloride salt of L-lysine

Biochem/physiol Actions

L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.

Side effects

L-Lysine hydrochloride may cause side effects such as stomach pain and diarrhea.

Safety Profile

L-Lysine hydrochloride is hazardous by inhalation. When heated to decomposition it emits very toxic fumes of HCl and NOx.

Purification Methods

Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]

Global( 978)Suppliers
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Hebei Chuanghai Biotechnology Co., Ltd
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View Lastest Price from L-Lysine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Lysine hydrochloride pictures 2026-06-05 L-Lysine hydrochloride
657-27-2
1KG 98.5%-101.5% 10 TONS WUHAN FORTUNA CHEMICAL CO., LTD
L-Lysine hydrochloride pictures 2026-06-05 L-Lysine hydrochloride
657-27-2
0.99 RongNa Biotechnology Co.,Ltd
L-Lysine HCl pictures 2026-05-28 L-Lysine HCl
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$10.00 1KG 98% 5000kg/Month Hebei Chuanghai Biotechnology Co,.LTD
  • L-Lysine HCl pictures
  • L-Lysine HCl
    657-27-2
  • $10.00
  • 98%
  • Hebei Chuanghai Biotechnology Co,.LTD
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