L-Lysine hydrochloride
- CAS No.
- 657-27-2
- Chemical Name:
- L-Lysine hydrochloride
- Synonyms
- L-LYSINE HCL;L-LYSINE MONOHYDROCHLORIDE;LYSINE HCL;LYSINE HYDROCHLORIDE;LYSINE MONOHYDROCHLORIDE;L-Lysine HCl USP;monohydrochloride,l-lysin;Lysine Hydrochloride, Powder;L-LYS HCL;L-LYSINE HYDROCHLORIDE USP
- CBNumber:
- CB5180129
- Molecular Formula:
- C6H14N2O2.ClH
- Molecular Weight:
- 182.65
- MDL Number:
- MFCD00064564
- MOL File:
- 657-27-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (S)-(+)-Lysine monohydrochloride for synthesis | 8.16018 | 100g | $57.7 |
| Lysine hydrochloride European Pharmacopoeia (EP) Reference Standard | L0900000 | 50 mg | $254 |
| (S)-(+)-Lysine monohydrochloride for synthesis | 8.16018 | 500g | $166 |
| L-Lysine, Hydrochloride An essential amino acid. | 4400-M | 100g | $71.4 |
| L-Lysine monohydrochloride BioUltra, ≥99.5% (AT) | 62929 | 100g | $77.8 |
| More product size | |||
| Melting point | 263 °C (dec.)(lit.) |
|---|---|
| alpha | 21 º (c=8, 6N HCl) |
| Density | 1.28 g/cm3 (20℃) |
| bulk density | 360kg/m3 |
| vapor pressure | <1 Pa (20 °C) |
| FEMA | 3847 | L-LYSINE |
| FLAVIS Number | 17.031 | L-(+)-Lysine monohydrochloride |
| storage temp. | 2-8°C |
| solubility | H2O: 100 mg/mL |
| form | powder |
| color | White to Off-white |
| Odor | odorless |
| PH | 5.5-6.0 (100g/l, H2O, 20℃) |
| biological source | non-animal source |
| optical activity | [α]20/D +20.5±0.5°, c = 5% in 5 M HCl |
| Water Solubility | 65 g/100 mL (20 ºC) |
| λmax |
λ: 260 nm Amax: 0.1 λ: 280 nm Amax: 0.1 |
| Merck | 14,5636 |
| BRN | 3563889 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Major Application | pharmaceutical (small molecule) |
| Cosmetics Ingredients Functions |
HAIR CONDITIONING SKIN CONDITIONING |
| Cosmetic Ingredient Review (CIR) | L-Lysine hydrochloride (657-27-2) |
| InChI | 1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1 |
| InChIKey | BVHLGVCQOALMSV-JEDNCBNOSA-N |
| SMILES | OC([C@@H](N)CCCCN)=O.[H]Cl |
| LogP | -1.036 (est) |
| CAS DataBase Reference | 657-27-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | JNJ23Q2COM |
| EPA Substance Registry System | Lysine hydrochloride (657-27-2) |
| UNSPSC Code | 41116107 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261-P271 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | ||||||||||
| WGK Germany | 2 | |||||||||
| RTECS | OL5650000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2922410000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
L-Lysine hydrochloride price More Price(126)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.16018 | (S)-(+)-Lysine monohydrochloride for synthesis | 657-27-2 | 100g | $57.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | L0900000 | Lysine hydrochloride European Pharmacopoeia (EP) Reference Standard | 657-27-2 | 50 mg | $254 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.16018 | (S)-(+)-Lysine monohydrochloride for synthesis | 657-27-2 | 500g | $166 | 2026-04-30 | Buy |
| Sigma-Aldrich | 4400-M | L-Lysine, Hydrochloride An essential amino acid. | 657-27-2 | 100g | $71.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 62929 | L-Lysine monohydrochloride BioUltra, ≥99.5% (AT) | 657-27-2 | 100g | $77.8 | 2026-04-30 | Buy |
L-Lysine hydrochloride Chemical Properties,Uses,Production
Synthesis
L-Lysine hydrochloride can be synthesisied by microbial fermentation to give crude L-Lysine , and then purified and synthesized by crystallization in hydrochloric acid.
Description
L-Lysine hydrochloride is a white or nearly white, practically odorless, free-flowing, crys talline powder. It is freely soluble in water, but is almost insoluble in alcohol and in ether. It melts at about 260°C with decomposition.
Chemical Properties
White crystalline powder
Uses
L-Lysine hydrochloride is widely used as nutritional supplements in food and beverage industries. It can also be used in animal feed as source of L-Lysine. It can be used in a wide variety of industries including: food production, beverage, pharmaceutical, agriculture/animal feed, and various other industries.
Definition
ChEBI: The hydrochloride salt of L-lysine
Biochem/physiol Actions
L-lysine is an essential amino acid in animals and humans. L-Lysine is necessary for protein synthesis in the body and proper growth. L-lysine lowers the cholesterol level by producing carnitine. L-lysine aids in calcium, zinc and iron absorption. Athletes take L-lysine as a supplement for lean mass building and for proper muscle and bone health. L-lysine competes with arginine during viral replication and reduces herpes simplex virus infection. L-lysine supplementation reduces chronic anxiety in human. Lysine reduces viscosity of serum albumin solution for injections.
Side effects
L-Lysine hydrochloride may cause side effects such as stomach pain and diarrhea.
Safety Profile
L-Lysine hydrochloride is hazardous by inhalation. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Purification Methods
Likely impurities are arginine, D-lysine, 2,6-diaminoheptanedioic acid and glutamic acid. Crystallise the monohydrochloride from water at pH 4-6 by adding 4 volumes of EtOH. At above 60% relative humidity it forms a dihydrate. [Birhbaum et al. J Biol Chem 194 455, 468 1952, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]
L-Lysine hydrochloride Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3587 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Suzhou Sanyi Polymer Chemical Technology Co., Ltd. | +8615571922873 | 15571922873@163.com | China | 102 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Shaanxi Franta Biotechnology Co., Ltd | +86-13082019107 | admin@flanderff.com | China | 244 | 58 |
| Shandong Juchuang Chemical Co., LTD | +16837774622 | admin@juchuangchem.com | China | 295 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
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View Lastest Price from L-Lysine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-05 | L-Lysine hydrochloride
657-27-2
|
1KG | 98.5%-101.5% | 10 TONS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
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2026-06-05 | L-Lysine hydrochloride
657-27-2
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
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2026-05-28 | L-Lysine HCl
657-27-2
|
$10.00 | 1KG | 98% | 5000kg/Month | Hebei Chuanghai Biotechnology Co,.LTD |
-

- L-Lysine hydrochloride
657-27-2
- 98.5%-101.5%
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- L-Lysine hydrochloride
657-27-2
- 0.99
- RongNa Biotechnology Co.,Ltd
-

- L-Lysine HCl
657-27-2
- $10.00
- 98%
- Hebei Chuanghai Biotechnology Co,.LTD
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