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Azosemide

Azosemide structure

CAS No.: 27589-33-9

Chemical Name:: Azosemide

Synonyms: Diart;Luret;SK-110;ple1053;azosemid;Diurapid;AZOSEMIDE;Azosemidum;AZOSEMIDE HPLC;Azosemide USP/EP/BP

CBNumber:: CB5200179

Molecular Formula:: C12H11ClN6O2S2

Molecular Weight:: 370.84

MDL Number:: MFCD00867321

MOL File:: 27589-33-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-03 11:24:09

Product description	Number	Pack Size	Price
Azosemide	A3544	1G	$164
Azosemide	FA44032	0.01g	$181.4
Azosemide	FA44032	0.025g	$272.1
Azosemide	FA44032	0.05g	$362.8
Azosemide	FA44032	0.1g	$453.51
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Azosemide Properties

Melting point	218-221°
Boiling point	221°C (rough estimate)
Density	1.6843 (rough estimate)
refractive index	1.6100 (estimate)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	3.58±0.10(Predicted)
color	Crystals
InChI	InChI=1S/C12H11ClN6O2S2/c13-9-5-10(15-6-7-2-1-3-22-7)8(12-16-18-19-17-12)4-11(9)23(14,20)21/h1-5,15H,6H2,(H2,14,20,21)(H,16,17,18,19)
InChIKey	HMEDEBAJARCKCT-UHFFFAOYSA-N
SMILES	C1(S(N)(=O)=O)=CC(C2=NNN=N2)=C(NCC2SC=CC=2)C=C1Cl
CAS DataBase Reference	27589-33-9(CAS DataBase Reference)
FDA UNII	MR40VT1L8Z

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319-H227
Precautionary statements	P501-P261-P270-P210-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312-P403+P235
Toxicity	LD50 orl-rat: 2545 mg/kg IYKEDH 18,666,87

Azosemide price More Price(113)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	A3544	Azosemide	27589-33-9	1G	$164	2026-04-30	Buy
Biosynth	FA44032	Azosemide	27589-33-9	0.01g	$181.4	2026-06-04	Buy
Biosynth	FA44032	Azosemide	27589-33-9	0.025g	$272.1	2026-06-04	Buy
Biosynth	FA44032	Azosemide	27589-33-9	0.05g	$362.8	2026-06-04	Buy
Biosynth	FA44032	Azosemide	27589-33-9	0.1g	$453.51	2026-06-04	Buy

Product number	Packaging	Price	Buy
A3544	1G	$164	Buy
FA44032	0.01g	$181.4	Buy
FA44032	0.025g	$272.1	Buy
FA44032	0.05g	$362.8	Buy
FA44032	0.1g	$453.51	Buy

Azosemide Chemical Properties,Uses,Production

Description

Azosemide is a high-ceiling diuretic similiar in structure and profile to furosemide, albeit somewhat less potent and less bioavailable. It is useful in the treatment of congestive heart failure and similar edematous conditions.

Chemical Properties

Crystallized, melting point 220-223℃.

Originator

Boehringer Manheim (W. Germany)

Uses

Diuretic.

Uses

Azosemide is a high-ceiling diuretic agent. It is used in the treatment of edematous states and hypertension.

Definition

ChEBI: A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hyp rtension.

Manufacturing Process

The 4-chloro-5-sulfamoyl-2-thenylaminobenzonitrile used as starting material is obtained by the reaction of 4-chloro-2-fluoro-5-sutfamoyl-benzonitrile with thenylamine in anhydrous tetrahydrofuran.
Then the 5-(4'-chloro-5'-sulfamoyl-2'-thenylamino)phenyltetrazole (MP 218° to 221°C, yield 37% of theory) is obtained by the reaction of 4-chloro-5- sulfamoyl-2-thenylaminobenzonitrite (MP 170° to 174°C) with sodium azide and ammonium chloride,

brand name

LURET

Therapeutic Function

Diuretic

Safety Profile

Poison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Whenheated to decomposition it emits toxic fumes of Cl^-, SOx,and NOx.

Azosemide Preparation Products And Raw materials

Raw materials

Sodium azide Benzonitrile 2-thiophene

Preparation Products

Azosemide Suppliers

Global( 119)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Tianjin Zhongxin Chemtech Co., Ltd.	86-22-66880623 +8618622897568	sales@tjzxchem.com	China	572	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Hebei Binshare New Material Co. Ltd	+8618633865755	china01@hbbinshare.com	CHINA	955	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32467	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Hebei Zhanyao Biotechnology Co. Ltd	15369953316 +8615369953316	admin@zhanyaobio.com	China	2123	58
Hubei Langyou International Trading Co., Ltd	+86-12345678900 +86-18874586545	linda@xrdchem.cn	China	196	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	28509	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Tianjin Zhongxin Chemtech Co., Ltd.	58
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Hebei Binshare New Material Co. Ltd	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hebei Zhanyao Biotechnology Co. Ltd	58
Hubei Langyou International Trading Co., Ltd	58
Dideu Industries Group Limited	58

View Lastest Price from Azosemide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-02	Azosemide 27589-33-9	$41.00-89.00		99.84%	10g	TargetMol Chemicals Inc.
2026-06-02	Azosemide 27589-33-9	$41.00-89.00		99.84%	10g	TargetMol Chemicals Inc.
2026-02-25	Azosemide 27589-33-9	$1.00	1g	99%	300tons	Hebei Dangtong Import and export Co LTD

Azosemide
27589-33-9
$41.00-89.00
99.84%
TargetMol Chemicals Inc.

Azosemide
27589-33-9
$41.00-89.00
99.84%
TargetMol Chemicals Inc.

Azosemide
27589-33-9
$1.00
99%
Hebei Dangtong Import and export Co LTD

Azosemide Spectrum

Azosemide(27589-33-9)¹HNMR

27589-33-9(Azosemide)Related Search:

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Polyamide Chlorantraniliprole Nicotinamide Formamide Sulfanilamide

N,N-Dimethylformamide Difluorochloromethane Chloroacetic acid

1of4

2-chloro-5-(1h-tetrazol-5-yl)-4-((2-thienylmethyl)amino)-benzenesulfonamid 2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenyl-sulfanilamid SK-110 2-chloro-5-(2H-1,2,3,4-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide 2-chloro-5-(2H-tetrazol-5-yl)-4-(2-thienylmethylamino)benzenesulfonamide 2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide Azosemide Solution, 1000ppm Azosemide Solution, 100ppm Pharmaceutical Intermediate 98% Research Powder cas 27589-33-9 Azosemide 2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenylsulfanilamide 5-(4’-chloro-5’-sulfamoyl-2’-thenylaminophenyl)-tetrazole azosemid ple1053 AZOSEMIDE 2-chloro-5-(1h-tetrazol-5-yl)-4-(2-thenylamino)benzenesulphonamide 2-CHLORO-5-(1H-TETRAZOL-5-YL)-4-((2-THIENYLMETHYL)AMINO)-BENZENESULFONAMIDE Azosemide(Chemical Name: 2-Chloro-5-(1h-Tertrazol-5-Yl)-N4-(2-Thenyl)) AZOSEMIDE HPLC Diart Diurapid Luret 2-Chloro-5-(1H-tetrazol-5-y1)-4-[(2-thienylmethyl)amino]benzenesulfona-Mide Azosemidum Pharmaceutical Intermediate 98% Research Powder Azosemide Benzenesulfonamide, 2-chloro-5-(2H-tetrazol-5-yl)-4-[(2-thienylmethyl)amino]- Azosemide USP/EP/BP 2-Chloro-5-(1H-tetrazol-5-yl)-4-[(thiophen-2-ylmethyl)amino]benzenesulfonamide Azosemide, 10 mM in DMSO 27589-33-9 C12H11CIN6O2S2 C12H11ClN6O2S2