Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2,2'-Dithiodipyridine

2,2'-Dithiodipyridine

2,2'-Dithiodipyridine Structure
2,2'-Dithiodipyridine structure
CAS No.
2127-03-9
Chemical Name:
2,2'-Dithiodipyridine
Synonyms
1,2-Di(pyridin-2-yl)disulfane;Aldrithiol;Dithiodipyridine;2-Aldrithiol;2-PDS;ALDRITHIOL-2;Dipyridyldisulfide;2-Pyridyl disulfide;1,2-Bis(2-pyridinyl) Disulfide;2PDS
CBNumber:
CB5200205
Molecular Formula:
C10H8N2S2
Molecular Weight:
220.31
MDL Number:
MFCD00006287
MOL File:
2127-03-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51
Product description Number Pack Size Price
Aldrithiol?-2 98% 143049 1g $31.5
2,2′-Dipyridyl disulfide for synthesis 8.41109 5G $141
Aldrithiol?-2 98% 143049 5g $141
2,2'-Dipyridyl Disulfide [for Peptide Synthesis] >98.0%(GC)(T) D1114 5g $53
2,2'-Dipyridyl Disulfide [for Peptide Synthesis] >98.0%(GC)(T) D1114 25g $145
More product size
Request For Quotation

2,2'-Dithiodipyridine Properties

Melting point 56-58 °C(lit.)
Boiling point 356.1±17.0 °C(Predicted)
Density 1.3078 (rough estimate)
refractive index 1.5500 (estimate)
Flash point 210 °C
storage temp. 2-8°C
solubility methanol: soluble50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow
pka 1.52±0.19(Predicted)
form powder
color Clear colorless to yellow to tan
Water Solubility 5 g/L (20 ºC)
BRN 154629
InChI 1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H
InChIKey HAXFWIACAGNFHA-UHFFFAOYSA-N
SMILES S(Sc1ccccn1)c2ccccn2
LogP 2.530 (est)
CAS DataBase Reference 2127-03-9(CAS DataBase Reference)
FDA UNII L6X912UPBU
NIST Chemistry Reference Pyridine, 2,2'-dithiobis-(2127-03-9)
EPA Substance Registry System Pyridine, 2,2'-dithiobis- (2127-03-9)
UNSPSC Code 12352113
NACRES NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-37-20/22
Safety Statements  36/37/39-37/39-25-22-36-26
RIDADR  UN 3335
WGK Germany  3
F  10-23
Autoignition Temperature 340 °C
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
0
2 0

2,2'-Dithiodipyridine price More Price(85)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 143049 Aldrithiol?-2 98% 2127-03-9 1g $31.5 2026-04-30 Buy
Sigma-Aldrich 8.41109 2,2′-Dipyridyl disulfide for synthesis 2127-03-9 5G $141 2026-04-30 Buy
Sigma-Aldrich 143049 Aldrithiol?-2 98% 2127-03-9 5g $141 2026-04-30 Buy
TCI Chemical D1114 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] >98.0%(GC)(T) 2127-03-9 5g $53 2026-04-30 Buy
TCI Chemical D1114 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] >98.0%(GC)(T) 2127-03-9 25g $145 2026-04-30 Buy
Product number Packaging Price Buy
143049 1g $31.5 Buy
8.41109 5G $141 Buy
143049 5g $141 Buy
D1114 5g $53 Buy
D1114 25g $145 Buy

2,2'-Dithiodipyridine Chemical Properties,Uses,Production

Chemical Properties

white to yellowish crystalline powder

Uses

2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols and activating or protecting carboxylic acid with triphenylphosphine.

Uses

2,2'-Dipyridyl disulfide is a useful reagent for determination of sulfhydryl groups, preparation of amino acid active esters and the thio esters of phosphoric acid. It acts as a peptide coupling reagent and as an oxidizing agent. It is also used for the activation of glycosides.

Uses

2,2'-Dithiodipyridine was used in the synthesis of adenosine-5′-phosphoimidazolide. It was employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation.

Definition

ChEBI: Aldrithiol is a member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols. It has a role as an oxidising agent. It is an organic disulfide and a member of pyridines.

General Description

2,2'-Dithiodipyridine is a nucleocapsid zinc finger targeting compound and can abrogate the infectivity of human immunodeficiency virus type-1 virions. It is a thiol reagent.

Biochem/physiol Actions

2,2′-Dithiodipyridine mediates inter-unit disulfide cross-linking. It interacts with carbon nucleophiles to yield thiopyridyl derivatives.

Purification Methods

Recrystallise the disulfide H2O from *C6H6/pet ether (6:7), ligroin or *C6H6. The picrate has m 119o (from EtOH). [Walter et al. Justus Liebigs Ann Chem 695 7785 1966, Marckwald et al. Chem Ber 33 1556 1900, Brocklehurst & Little Biochem J 133 67,78 1973, Beilstein 21 III/IV 48.] It has been used as a 1mM solution in EtOH for the spectrophotometric estimation of thiols. Essentially the thiol displaces half the disulfide molecule liberating the 2-mercaptopyridine anion, thereby shifting the from 340nm (of the disulfide) to 268nm (of the anion) at pH 9, or 278nm in H2O. (Compare

2,2'-Dithiodipyridine synthesis

2637-34-5
2127-03-9
Synthesis of 2,2'-Dithiodipyridine from 2-Pyridinethione

2,2'-Dithiodipyridine Preparation Products And Raw materials

Raw materials

Pyrithione Bispyrithione

Preparation Products

Finasteride PYRIDINE-2-SULFONYL CHLORIDE Pyridine,2-(2-propen-1-ylthio)- 2-Pyridinesulfonamide(6CI,7CI,9CI) 2-Methylthiopyridine
2-(ethenesulfonyl)pyridine

1of2

2,2'-Dithiodipyridine Suppliers

Global( 361)Suppliers
Supplier Tel Email Country ProdList Advantage
Shijiazhuang Jianxin Biotechnology Co., LTD
+undefined-86-1906231316-9 +undefined86-19062313169 liyingjian1997@gmail.com China 712 58
Suzhou Highfine Biotech Co.,Ltd.
+86-0512-68071238 +86-13771819922 june@highfine.com China 489 58
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Anhuyan (Hainan) Biotechnology Co., LTD 		+8618163349544 mollylucking@foxmail.com China 3000 58
Moxin Chemicals 		+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Capot Chemical Co.,Ltd. 		+8613336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13901 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21588 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Supplier Advantage
Shijiazhuang Jianxin Biotechnology Co., LTD
58
Suzhou Highfine Biotech Co.,Ltd.
58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Anhuyan (Hainan) Biotechnology Co., LTD 		58
Moxin Chemicals 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60

View Lastest Price from 2,2'-Dithiodipyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2'-Dithiodipyridine pictures 2026-05-22 2,2'-Dithiodipyridine
2127-03-9
 US $0.00 / G/KG 1G/KG 99% 100000000KG Anhuyan (Hainan) Biotechnology Co., LTD
2,2'-Dithiodipyridine pictures 2026-05-15 2,2'-Dithiodipyridine
2127-03-9
 US $0.00 / GK 1GK 98% 1-10mt Baoji Guokang Healthchem Co., Ltd.
2,2′-Dipyridyl disulfide pictures 2026-05-11 2,2′-Dipyridyl disulfide
2127-03-9
 US $52.00 / g 99.94% 10g TargetMol Chemicals Inc.

2,2'-Dithiodipyridine Spectrum

2,2'-Dithiodipyridine(2127-03-9)MS2,2'-Dithiodipyridine(2127-03-9)1HNMR2,2'-Dithiodipyridine(2127-03-9)13CNMR2,2'-Dithiodipyridine(2127-03-9)IR12,2'-Dithiodipyridine(2127-03-9)Raman

2127-03-9(2,2'-Dithiodipyridine )Related Search:

2,5-PYRIDINEDICARBOXYLIC ACID Diallyldisulfide Dimethyl disulfide THIODIGLYCOLIC ACID 2,2'-Bipyridine
Pyridine Dibenzyl disulfide 2,6-Lutidine Allicin Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
2,2'-DITHIOBIS(5-NITROPYRIDINE) 6,6'-DITHIODINICOTINIC ACID Bispyrithione 4,4'-DITHIODIPYRIDINE,4,4Dipyridyldisulfide-(4,4dithiodipyridine) GGKPDLRPCHPPCHYIPRPKPR
2,2'-Dithiodipyridine 4,4'-DIPYRIDYL DISULPHIDE, (4,4'-DITHIODIPYRIDINE) DI[5-(TRIFLUOROMETHYL)-2-PYRIDYL] DISULFIDE

1of4

NSC 94055 2,2'-Disulphanediyldipyridine, 2,2'-Dithiodipyridine Di(pyridin-2-yl) disulphide Aldrithiol(TM)-2 98% 1,2-Di(pyridin-2-yl)disulfide 2-(2-Pyridinyldisulfanyl)pyridine 2,2'-Dipyridinyl disulfide 2,2'-Dithiobis(pyridine) 2,2'-Dithiopyridine 2-Dipyridyl disulfide 2PDS 2-Pyridyl disulfide Aldrithol-2 2,2'-Dithiodipyridine, >=99% Bis(pyridin-2-yl) disulfide 2,2μ-Dipyridyl disulfide, 2,2μ-Dithiodipyridine Aldritiol Di(2-pyridyl) persulfide 2,2'-Dithiodipyridine,98% 2,2'-Dithiodipyridin Bis(pyridin-2-yl) disulphide 2,2'- Dipyridil disulfide 2-(pyridin-2-yldisulfanyl)pyridine 1,2-Bis(2-pyridinyl) Disulfide 2,2'-Bipyridyldisulfide 2-Aldrithiol 1,2-Di(pyridin-2-yl Bis(2-pyridinyl) disulfide Bis(2-pyridyl) disulfide Di-2-Pyridyl disulfide Nsc 677438 Pyridine, 2,2'-dithiodi- ALDRITHIOL(TM)-2 2,2'-DIPYRIDYL DISULPHIDE 2-(PYRIDIN-2-YLDITHIO)PYRIDINE 2-PYRIDINYL DISULFIDE 2,2'-Dipyridyl Disulfide [for Peptide Synthesis] Pyridine, 2,2-dithiobis- 2,2''-DIPYRIDYL DISULFIDE 98+% Di(pyridin-2-yl) disulfide 2,2'-Dipyridyl disulfide, 98%, for synthesis 2,2'-DipyridylDisulfide[forPeptideSynthesis]> 2,2'-DIPYRIDYL DISULFIDE FOR SYNTHESIS 2,2'-Dithiodipyridine ISO 9001：2015 REACH 2-(2-Pyridyldisulfanyl)pyridine 9-[(3aS,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-3H-purin-6-one 2,2'-Dithiodipyridine 2,2'-Dipyridyl disulfide 2,2'-Dipyridyl disulfide|||OPSS|||Aldrithiol 2|||Orthopyridyl disulfide 2,2''-Dithiodipyridine 2,2'-Dithiodipyridin Aldrithiol?-2 2,2 '- Dipyridine Disulfide 2,2'-Dithiodipyridine 2,2'-Dipyridyldisulfide 2'-Dithiodipyridine 1,2-Di(pyridin-2-yl)disulfane Aldrithiol