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betamethasone 21-mesylate

CAS No.
1881-66-9
Chemical Name:
betamethasone 21-mesylate
Synonyms
betamethasone 21-methanesulfonate;betamethasone 21-mesylate;Betamethasone Impurity 40;Betamethasone 21-Mesylate (>Betamethasone 21-Mesylate (>90%);Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(methylsulfonyl)oxy]-, (11β,16β)-;2-((8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl methanesulfonate;2-((8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl methanesulfonate (Betamethasone impurity)
CBNumber:
CB52078729
Molecular Formula:
C23H31FO7S
Molecular Weight:
470.55
MDL Number:
MOL File:
1881-66-9.mol
Last updated:2026-05-28 01:18:49

betamethasone 21-mesylate Properties

Melting point >174°C (dec.)
Boiling point 652.3±55.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka 11.93±0.70(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H373-H360
Precautionary statements  P260-P314-P501

betamethasone 21-mesylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-B326993-100MG Betamethasone 21-Mesylate (>90%) 1881-66-9 100mg $1340 2026-06-03 Buy
aablocks AA00AVNU Betamethasone 21-Mesylate (>90%) 1881-66-9 100mg $1192 2026-05-28 Buy
TRC B326993 Betamethasone21-Mesylate(>90%) 1881-66-9 25mg $275 2021-12-16 Buy
Product number Packaging Price Buy
TRC-B326993-100MG 100mg $1340 Buy
AA00AVNU 100mg $1192 Buy
B326993 25mg $275 Buy

betamethasone 21-mesylate Chemical Properties, Uses, Production

Uses

Betamethasone 21-Mesylate is an intermediate in synthesizing Doxybetasol (Betamethasone Valerate EP Impurity B) (D561000), which is an impurity of Betamethasone (B327000). It is a glucocorticoid used as an anti-inflammatory agent.

betamethasone 21-mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

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betamethasone 21-mesylate Betamethasone 21-Mesylate (> Betamethasone Impurity 40 Betamethasone 21-Mesylate (>90%) Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(methylsulfonyl)oxy]-, (11β,16β)- 2-((8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl methanesulfonate betamethasone 21-methanesulfonate 2-((8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl methanesulfonate (Betamethasone impurity) 1881-66-9