ChemicalBook >> CAS DataBase List >>6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
- CAS No.
- 937049-58-6
- Chemical Name:
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
- Synonyms
- 1H-Indazole-6-boronic acid picol ester;Indazole-6-boronic acid pinacolate;Pinacol ester indazole-6-boronic acid;Indazole-6-yl-boronic acid pinacol ester;1H-Indazole-6-boronic acid pinacol ester;6-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole;6-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE;1H-Indazole, 6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole, 2-(1H-Indazol-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- CBNumber:
- CB52130144
- Molecular Formula:
- C13H17BN2O2
- Molecular Weight:
- 244.1
- MDL Number:
- MFCD07368067
- MOL File:
- 937049-58-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 01:27:17
| Product description | Number | Pack Size | Price |
| 1H-Indazole-6-boronic acid pinacol ester ≥95% | 692735 | 1g | $164 |
| 1H-Indazole-6-boronic acid pinacol ester ≥95% | 692735 | 5g | $569 |
| 1H-Indazole-6-boronic acid, pinacol ester 97% | OR30736 | 1g | $41 |
| 1H-Indazole-6-boronic acid, pinacol ester 97% | OR30736 | 5g | $109 |
| 1H-Indazole-6-boronic acid, pinacol ester 97% | OR30736 | 10g | $204 |
| More product size | |||
| Melting point | 134-139°C |
|---|---|
| Boiling point | 404.1±18.0 °C(Predicted) |
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 13.78±0.40(Predicted) |
| color | White |
| InChI | InChI=1S/C13H17BN2O2/c1-12(2)13(3,4)18-14(17-12)10-6-5-9-8-15-16-11(9)7-10/h5-8H,1-4H3,(H,15,16) |
| InChIKey | YDWZPHAJTNZBEG-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC(B3OC(C)(C)C(C)(C)O3)=C2)C=N1 |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| WGK Germany | 3 |
| HS Code | 2933998090 |
| Storage Class | 13 - Non Combustible Solids |
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole price More Price(72)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 692735 | 1H-Indazole-6-boronic acid pinacol ester ≥95% | 937049-58-6 | 1g | $164 | 2023-01-07 | Buy |
| Sigma-Aldrich | 692735 | 1H-Indazole-6-boronic acid pinacol ester ≥95% | 937049-58-6 | 5g | $569 | 2022-05-15 | Buy |
| Apolloscientific | OR30736 | 1H-Indazole-6-boronic acid, pinacol ester 97% | 937049-58-6 | 1g | $41 | 2026-06-04 | Buy |
| Apolloscientific | OR30736 | 1H-Indazole-6-boronic acid, pinacol ester 97% | 937049-58-6 | 5g | $109 | 2026-06-04 | Buy |
| Apolloscientific | OR30736 | 1H-Indazole-6-boronic acid, pinacol ester 97% | 937049-58-6 | 10g | $204 | 2026-06-04 | Buy |
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole Chemical Properties,Uses,Production
Synthesis
79762-54-2
73183-34-3
937049-58-6
6-Bromo-1H-indazole (700 mg, 3.55 mmol) and pinacol ester of bisboronic acid (1.50 g, 5.91 mmol) were used as raw materials, and both were mixed with Pd(dppf)Cl2-DCM (290 mg, 0.36 mmol) and KOAc (1.04 g, 10.6 mmol) in DMF (20 mL) under nitrogen protection. . The reaction mixture was stirred at 100 °C for 15 hours. Upon completion of the reaction, the mixture was concentrated in vacuum and the residue was suspended in EtOAc (30 mL), filtered through diatomaceous earth, and the filtrate was concentrated to give 866 mg (100% yield) of 1H-indazole-6-boronic acid pinacol ester as a brown semi-solid, which could be used for the subsequent reaction without further purification.Results of LC-MS analysis: C13H17BN2O2 + H+ [M + H]+ , calculated value 245.1, measured value 245.0.
References
[1] Patent: WO2015/140717, 2015, A1. Location in patent: Page/Page column 87; 88
[2] Patent: WO2017/68064, 2017, A1. Location in patent: Page/Page column 182
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 10, p. 4458 - 4473
[4] Patent: US2007/203143, 2007, A1. Location in patent: Page/Page column 50
[5] RSC Advances, 2017, vol. 7, # 44, p. 27737 - 27746
Synthesis of 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole from 6-Bromoindazole and Bis(pinacolato)diboron
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 133)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
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| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14303 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9047 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10457 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
937049-58-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
937049-58-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-09-03 | 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
937049-58-6
|
$7.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
937049-58-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
937049-58-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
937049-58-6
- $7.00
- 99%
- Career Henan Chemical Co
937049-58-6(6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole)Related Search:
7-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE
6-INDAZOLYBORONIC ACID
tert-butyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole-1-carboxylate
3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
4-Methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indazole
1of2
6-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE
6-(tetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
1H-Indazole, 6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole, 2-(1H-Indazol-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Pinacol ester indazole-6-boronic acid
Indazole-6-yl-boronic acid pinacol ester
Indazole-6-boronic acid pinacolate
1H-Indazole-6-boronic acid pinacol ester
1H-Indazole-6-boronic acid picol ester
937049-58-6
