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2-Fluoro-3-iodopyridine

2-Fluoro-3-iodopyridine structure

CAS No.: 113975-22-7

Chemical Name:: 2-Fluoro-3-iodopyridine

Synonyms: uoro-3-iodopyridine;2-FLUORO-3-IODOPYRIDINE;2-Fluoro-3-iodopyridine>PYRIDINE, 2-FLUORO-3-IODO-;2-Fluoro-3-Iodopyridine 98%;2-Fluoro-3-iodopyridine ,98%;2-Fluoro-3-iodopyridine, 97+%;2-Fluoro-3-iodopyridine ISO 9001：2015 REACH

CBNumber:: CB5228823

Molecular Formula:: C5H3FIN

Molecular Weight:: 222.99

MDL Number:: MFCD03095287

MOL File:: 113975-22-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:16:22

Product description	Number	Pack Size	Price
2-Fluoro-3-iodopyridine 97%	755389	1g	$68
2-Fluoro-3-iodopyridine >98.0%(GC)	F0733	1g	$42
2-Fluoro-3-iodopyridine >98.0%(GC)	F0733	5g	$139
2-Fluoro-3-iodopyridine 98+% (GC) ≥98%(GC)	230319	1g	$163
2-Fluoro-3-iodopyridine 98+% (GC) ≥98%(GC)	230319	5g	$206
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2-Fluoro-3-iodopyridine Properties

Melting point	45 °C
Boiling point	99°C/17mmHg(lit.)
Density	2.046±0.06 g/cm3(Predicted)
Flash point	>110°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	-2.45±0.10(Predicted)
color	White to Light yellow
Sensitive	Light Sensitive
InChI	1S/C5H3FIN/c6-5-4(7)2-1-3-8-5/h1-3H
InChIKey	WCDCAXVNBOLWNO-UHFFFAOYSA-N
SMILES	Fc1ncccc1I
CAS DataBase Reference	113975-22-7(CAS DataBase Reference)
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H319-H302-H315-H318-H335

Precautionary statements

P261-P280a-P304+P340-P405-P501a-P280-P305+P351+P338-P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Hazard Codes

Xn,Xi

Risk Statements

20/21/22-36/37/38-41-37/38

Safety Statements

22-26-36/37/39-39-37

WGK Germany

Hazard Note

Irritant

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2

NFPA 704

	1
2		0

2-Fluoro-3-iodopyridine price More Price(93)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	755389	2-Fluoro-3-iodopyridine 97%	113975-22-7	1g	$68	2023-06-20	Buy
TCI Chemical	F0733	2-Fluoro-3-iodopyridine >98.0%(GC)	113975-22-7	1g	$42	2026-04-30	Buy
TCI Chemical	F0733	2-Fluoro-3-iodopyridine >98.0%(GC)	113975-22-7	5g	$139	2026-04-30	Buy
Usbiological	230319	2-Fluoro-3-iodopyridine 98+% (GC) ≥98%(GC)	113975-22-7	1g	$163	2026-06-03	Buy
Usbiological	230319	2-Fluoro-3-iodopyridine 98+% (GC) ≥98%(GC)	113975-22-7	5g	$206	2026-06-03	Buy

Product number	Packaging	Price	Buy
755389	1g	$68	Buy
F0733	1g	$42	Buy
F0733	5g	$139	Buy
230319	1g	$163	Buy
230319	5g	$206	Buy

2-Fluoro-3-iodopyridine Chemical Properties,Uses,Production

Chemical Properties

Salmon-coloured solid

Uses

2-Fluoro-3-iodopyridine is typically used in scientific research and should not be used as a medicine, home remedy, or for other purposes.

Synthesis

372-48-5

113975-22-7

General procedure for the synthesis of 2-fluoro-3-iodopyridine from 2-fluoropyridine: LDA (25.8 mL of a 2M THF solution, 51.5 mmol) was added slowly and dropwise to an anhydrous THF (50 mL) solution of 2-fluoropyridine (5.0 g, 51.5 mmol) at -78 °C. The reaction mixture was stirred continuously at -78 °C for 1 hour. Subsequently, a THF (30 mL) solution of I2 (13.07 g, 51.5 mmol) was added dropwise to the reaction system at the same temperature. After the reaction mixture continued to be stirred at -78 °C for 3 h, the reaction was quenched by the addition of H2O (10 mL) and slowly warmed to room temperature. Na2SO3 (50 mL, 2 M solution in water) was added to remove excess iodine. The organic layer was separated, washed with brine, dried over anhydrous Na2SO4 and then concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford 2-fluoro-3-iodopyridine (9.6 g, 83.6% yield) as a white solid. lC/MS analysis: m/z (M++H) = 224.

References

[1] Patent: EP1559320, 2005, A1. Location in patent: Page/Page column 6
[2] Journal of Organic Chemistry, 2002, vol. 67, # 10, p. 3487 - 3493
[3] Tetrahedron Letters, 2004, vol. 45, # 36, p. 6697 - 6701
[4] Patent: WO2013/6792, 2013, A1. Location in patent: Paragraph 0188
[5] Tetrahedron, 2004, vol. 60, # 29, p. 6113 - 6120

2-Fluoro-3-iodopyridine synthesis

Synthesis of 2-Fluoro-3-iodopyridine from 2-Fluoropyridine

2-Fluoro-3-iodopyridine Preparation Products And Raw materials

Raw materials

3-Bromo-2-fluoropyridine 2-Fluoro-4-iodopyridine Tetrahydrofuran Lithium diisopropylamide 2-Chloro-3-iodopyridine

2-Fluoropyridine

1of2

Preparation Products

2-Fluoro-3,6-diiodopyridine 3-Iodo-2-methoxypyridine 3-Iodopyridin-2-amine 3-Benzyl-2-fluoro-4-iodopyridine 2-Fluoro-4-iodo-3-(2-methylallyl)pyridine

4-iodo-3-isopropyl-1H-pyrazolo[3,4-b]pyridine 3-cyclopropyl-2-fluoropyridine

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2-Fluoro-3-iodopyridine Suppliers

Global( 374)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20122	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	880	50
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	14014	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hi-Tech Chemistry Corp	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58

View Lastest Price from 2-Fluoro-3-iodopyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-01	2-Fluoro-3-iodopyridine 113975-22-7		1KG	98.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-11-18	2-Fluoro-3-iodopyridine 113975-22-7	$1.10	1g	99.00%	100 Tons min	Dideu Industries Group Limited
2025-09-25	2-Fluoro-3-iodopyridine 113975-22-7	$1.00-200.00	1KG	99%, 99.5% Sublimated		Henan Fengda Chemical Co., Ltd

2-Fluoro-3-iodopyridine
113975-22-7
98.0%
Shaanxi Dideu New Materials Co. Ltd

2-Fluoro-3-iodopyridine
113975-22-7
$1.10
99.00%
Dideu Industries Group Limited

2-Fluoro-3-iodopyridine
113975-22-7
$1.00-200.00
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

2-Fluoro-3-iodopyridine Spectrum

2-Fluoro-3-iodopyridine(113975-22-7)¹HNMR

113975-22-7(2-Fluoro-3-iodopyridine)Related Search:

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PYRIDINE, 2-FLUORO-3-IODO- 2-FLUORO-3-IODOPYRIDINE 2-Fluoro-3-iodopyridine ,98% 2-Fluoro-3-Iodopyridine 98% 2-Fluoro-3-iodopyridine, 97+% 2-Fluoro-3-iodopyridine> uoro-3-iodopyridine 2-Fluoro-3-iodopyridine ISO 9001：2015 REACH 113975-22-7 Building Blocks C5 Chemical Synthesis Propidium heterocyclic series Heterocycle Pyridine Pyridine series Halides Pyridines Fluorine series alkyl Iodine| alkyl Fluorine Fluorinated Building Blocks Heterocyclic Building Blocks Heterocyclic Fluorinated Building Blocks New Products for Chemical Synthesis Other Fluorinated Heterocycles