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2-Fluoro-3-iodopyridine

2-Fluoro-3-iodopyridine Structure
2-Fluoro-3-iodopyridine structure
CAS No.
113975-22-7
Chemical Name:
2-Fluoro-3-iodopyridine
Synonyms
uoro-3-iodopyridine;2-FLUORO-3-IODOPYRIDINE;2-Fluoro-3-iodopyridine>PYRIDINE, 2-FLUORO-3-IODO-;2-Fluoro-3-Iodopyridine 98%;2-Fluoro-3-iodopyridine ,98%;2-Fluoro-3-iodopyridine, 97+%;2-Fluoro-3-iodopyridine ISO 9001：2015 REACH
CBNumber:
CB5228823
Molecular Formula:
C5H3FIN
Molecular Weight:
222.99
MDL Number:
MFCD03095287
MOL File:
113975-22-7.mol
MSDS File:
SDS
Last updated:2026-01-13 11:21:55
Product description Number Pack Size Price
2-Fluoro-3-iodopyridine 97% 755389 1g $68
2-Fluoro-3-iodopyridine >98.0%(GC) F0733 1g $42
2-Fluoro-3-iodopyridine >98.0%(GC) F0733 5g $139
2-Fluoro-3-iodopyridine F598830 250mg $55
2-Fluoro-3-iodopyridine F598830 500mg $65
More product size
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2-Fluoro-3-iodopyridine Properties

Melting point 45 °C
Boiling point 99°C/17mmHg(lit.)
Density 2.046±0.06 g/cm3(Predicted)
Flash point >110°C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form powder to crystal
pka -2.45±0.10(Predicted)
color White to Light yellow
Sensitive Light Sensitive
InChI 1S/C5H3FIN/c6-5-4(7)2-1-3-8-5/h1-3H
InChIKey WCDCAXVNBOLWNO-UHFFFAOYSA-N
SMILES Fc1ncccc1I
CAS DataBase Reference 113975-22-7(CAS DataBase Reference)
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H319-H302-H315-H318-H335
Precautionary statements  P261-P280a-P304+P340-P405-P501a-P280-P305+P351+P338-P264-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38-41-37/38
Safety Statements  22-26-36/37/39-39-37
WGK Germany  3
Hazard Note  Irritant
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
NFPA 704
1
2 0

2-Fluoro-3-iodopyridine price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 755389 2-Fluoro-3-iodopyridine 97% 113975-22-7 1g $68 2023-06-20 Buy
TCI Chemical F0733 2-Fluoro-3-iodopyridine >98.0%(GC) 113975-22-7 1g $42 2026-03-19 Buy
TCI Chemical F0733 2-Fluoro-3-iodopyridine >98.0%(GC) 113975-22-7 5g $139 2026-03-19 Buy
TRC F598830 2-Fluoro-3-iodopyridine 113975-22-7 250mg $55 2021-12-16 Buy
TRC F598830 2-Fluoro-3-iodopyridine 113975-22-7 500mg $65 2021-12-16 Buy
Product number Packaging Price Buy
755389 1g $68 Buy
F0733 1g $42 Buy
F0733 5g $139 Buy
F598830 250mg $55 Buy
F598830 500mg $65 Buy

2-Fluoro-3-iodopyridine Chemical Properties,Uses,Production

Chemical Properties

Salmon-coloured solid

Uses

2-Fluoro-3-iodopyridine is typically used in scientific research and should not be used as a medicine, home remedy, or for other purposes.

Synthesis

2-Fluoropyridine

372-48-5

2-Fluoro-3-iodopyridine

113975-22-7

General procedure for the synthesis of 2-fluoro-3-iodopyridine from 2-fluoropyridine: LDA (25.8 mL of a 2M THF solution, 51.5 mmol) was added slowly and dropwise to an anhydrous THF (50 mL) solution of 2-fluoropyridine (5.0 g, 51.5 mmol) at -78 °C. The reaction mixture was stirred continuously at -78 °C for 1 hour. Subsequently, a THF (30 mL) solution of I2 (13.07 g, 51.5 mmol) was added dropwise to the reaction system at the same temperature. After the reaction mixture continued to be stirred at -78 °C for 3 h, the reaction was quenched by the addition of H2O (10 mL) and slowly warmed to room temperature. Na2SO3 (50 mL, 2 M solution in water) was added to remove excess iodine. The organic layer was separated, washed with brine, dried over anhydrous Na2SO4 and then concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography to afford 2-fluoro-3-iodopyridine (9.6 g, 83.6% yield) as a white solid. lC/MS analysis: m/z (M++H) = 224.

References

[1] Patent: EP1559320, 2005, A1. Location in patent: Page/Page column 6
[2] Journal of Organic Chemistry, 2002, vol. 67, # 10, p. 3487 - 3493
[3] Tetrahedron Letters, 2004, vol. 45, # 36, p. 6697 - 6701
[4] Patent: WO2013/6792, 2013, A1. Location in patent: Paragraph 0188
[5] Tetrahedron, 2004, vol. 60, # 29, p. 6113 - 6120

2-Fluoro-3-iodopyridine synthesis

372-48-5
113975-22-7
Synthesis of 2-Fluoro-3-iodopyridine from 2-Fluoropyridine

2-Fluoro-3-iodopyridine Preparation Products And Raw materials

Raw materials

3-Bromo-2-fluoropyridine 2-Fluoro-4-iodopyridine Tetrahydrofuran Lithium diisopropylamide 2-Chloro-3-iodopyridine
2-Fluoropyridine

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Preparation Products

2-Fluoro-3,6-diiodopyridine 3-Iodo-2-methoxypyridine 3-Iodopyridin-2-amine 3-Benzyl-2-fluoro-4-iodopyridine 2-Fluoro-4-iodo-3-(2-methylallyl)pyridine
4-iodo-3-isopropyl-1H-pyrazolo[3,4-b]pyridine 3-cyclopropyl-2-fluoropyridine

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2-Fluoro-3-iodopyridine Suppliers

Global( 377)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20124 58
Frapp's ChemicalNFTZ Co., Ltd. 		+86 (576) 8169-6106 sales@frappschem.com China 880 50
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 13815 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Hi-Tech Chemistry Corp 		0519-86626038 yuhh@hitechem.com CHINA 810 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29822 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10404 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Frapp's ChemicalNFTZ Co., Ltd. 		50
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Hi-Tech Chemistry Corp 		58
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Jinan Carbotang Biotech Co.,Ltd. 		58

View Lastest Price from 2-Fluoro-3-iodopyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Fluoro-3-iodopyridine pictures 2025-12-01 2-Fluoro-3-iodopyridine
113975-22-7
 US $0.00-0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
2-Fluoro-3-iodopyridine pictures 2025-11-18 2-Fluoro-3-iodopyridine
113975-22-7
 US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited
2-Fluoro-3-iodopyridine pictures 2025-09-25 2-Fluoro-3-iodopyridine
113975-22-7
 US $200.00-1.00 / KG 1KG 99%, 99.5% Sublimated g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd

2-Fluoro-3-iodopyridine Spectrum

2-Fluoro-3-iodopyridine(113975-22-7)1HNMR

113975-22-7(2-Fluoro-3-iodopyridine)Related Search:

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PYRIDINE, 2-FLUORO-3-IODO- 2-FLUORO-3-IODOPYRIDINE 2-Fluoro-3-iodopyridine ,98% 2-Fluoro-3-Iodopyridine 98% 2-Fluoro-3-iodopyridine, 97+% 2-Fluoro-3-iodopyridine> uoro-3-iodopyridine 2-Fluoro-3-iodopyridine ISO 9001：2015 REACH 113975-22-7 Building Blocks C5 Chemical Synthesis Propidium heterocyclic series Heterocycle Pyridine Pyridine series Halides Pyridines Fluorine series alkyl Iodine| alkyl Fluorine Fluorinated Building Blocks Heterocyclic Building Blocks Heterocyclic Fluorinated Building Blocks New Products for Chemical Synthesis Other Fluorinated Heterocycles