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3'-Bromoacetophenone

CAS No.
2142-63-4
Chemical Name:
3'-Bromoacetophenone
Synonyms
1-(3-BROMOPHENYL)ETHAN-1-ONE;3-BROMOACETOPHENONE;1-(3-BROMOPHENYL)ETHANONE;M-BROMOACETOPHENONE;NSC 46620;M-bromophenone;AKOS BBS-00003235;3'-Bromacetophenon;3-bromoacetephenone;BROMOACETOPHENONE-3
CBNumber:
CB5233225
Molecular Formula:
C8H7BrO
Molecular Weight:
199.04
MDL Number:
MFCD00000083
MOL File:
2142-63-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:17:51
Product description Number Pack Size Price
3′-Bromoacetophenone ReagentPlus , 99% B56358 25g $70.3
3′-Bromoacetophenone ReagentPlus , 99% B56358 100g $118
3'-Bromoacetophenone >98.0%(GC) B0536 5g $17
3'-Bromoacetophenone >98.0%(GC) B0536 25g $46
3'-Bromoacetophenone TRC-B679363-500MG 500mg $59
More product size

3'-Bromoacetophenone Properties

Melting point 8-11 °C(lit.)
Boiling point 79-81 °C0.2 mm Hg
Density 1.505 g/mL at 25 °C(lit.)
refractive index n20/D 1.576(lit.)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
Water Solubility Practically insoluble in water
form Liquid
Specific Gravity 1.498
color Clear slightly yellow to yellow
BRN 507599
InChI 1S/C8H7BrO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,1H3
InChIKey JYAQYXOVOHJRCS-UHFFFAOYSA-N
SMILES CC(=O)c1cccc(Br)c1
CAS DataBase Reference 2142-63-4(CAS DataBase Reference)
NIST Chemistry Reference 3-Bromoacetophenone(2142-63-4)
EPA Substance Registry System Ethanone, 1-(3-bromophenyl)- (2142-63-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38-36/38
Safety Statements  26-36-24/25
WGK Germany  3
8
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29147090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
REACH Registrations Active
NFPA 704
1
2 0

3'-Bromoacetophenone price More Price(82)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B56358 3′-Bromoacetophenone ReagentPlus , 99% 2142-63-4 25g $70.3 2026-04-30 Buy
Sigma-Aldrich B56358 3′-Bromoacetophenone ReagentPlus , 99% 2142-63-4 100g $118 2026-04-30 Buy
TCI Chemical B0536 3'-Bromoacetophenone >98.0%(GC) 2142-63-4 5g $17 2026-04-30 Buy
TCI Chemical B0536 3'-Bromoacetophenone >98.0%(GC) 2142-63-4 25g $46 2026-04-30 Buy
TRC TRC-B679363-500MG 3'-Bromoacetophenone 2142-63-4 500mg $59 2026-06-03 Buy
Product number Packaging Price Buy
B56358 25g $70.3 Buy
B56358 100g $118 Buy
B0536 5g $17 Buy
B0536 25g $46 Buy
TRC-B679363-500MG 500mg $59 Buy

3'-Bromoacetophenone Chemical Properties,Uses,Production

Chemical Properties

Clear colourless to light yellow liquid

Uses

3''-Bromoacetophenone is a chemical reagent used in the synthesis of chalcone derivatives as anti-cancer agents. Also used in the preparation of biphenyl pyridazinone deriatives as PDE4 inhibitors in anti-inflammatory treatments.

Synthesis

80ml of 48% hydrobromic acid, 80ml of water and 23g m-amino acetophenone, with ice brine cold to 0 ~ 5 C, and then drop under stirring by 12.2g of sodium nitrite and 30ml of water solution (under the liquid level), and maintain the reaction temperature of 0 ~ 8 C. Drops, and continue to react for 30min. will be made above the diazonium salt solution is poured into the cold CuBr hydrochloric acid solution (27.5 gCuBr + 50 ml hydrobromic acid), heated to 50 ~ 65 , stirred thoroughly for 2 ~ 3h. Separate and remove the solid material and water phase, to obtain the oily material. The oily material was washed with water until the aqueous solution was neutral. The oily material was added to water and distilled with water vapor until there were no oil droplets. Separate the oil layer, the aqueous layer was extracted with benzene, and after combining the oil layers, the benzene was first vaporized at atmospheric pressure, and then distilled at reduced pressure to collect the fraction at 117-122C (2.3 kp), to obtain the product 3'-bromoacetophenone (31.2g, content 99.6%, yield 95.2%).

Global( 469)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd
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Shanghai Longyu Biotechnology Co., Ltd.
info@longyupharma.com China 2421 58

View Lastest Price from 3'-Bromoacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3'-Bromoacetophenone pictures 2026-05-21 3'-Bromoacetophenone
2142-63-4
1KG ≥99% 500mt/year Jinan Finer Chemical Co., Ltd
3'-Bromoacetophenone pictures 2025-06-27 3'-Bromoacetophenone
2142-63-4
$10.00-30.00 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
3'-Bromoacetophenone pictures 2025-06-20 3'-Bromoacetophenone
2142-63-4
$10.00-20.00 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
1-(3-bromophenyl)-ethanon 3'-Bromoacetophenone, 98+% Methyl(3-bromophenyl) ketone NSC 46620 3′-Bromoacetophenone,1-Acetyl-3-bromobenzene Between broMoacetophenone Meta BroMoacetophenone 3'-Bromacetophenon 3'-Bromoacetophenone Vetec(TM) reagent grade, 98% 3'-BROMOACETOPHENONE FOR SYNTHESIS 3'-BroMoacetophenone ReagentPlus(R), 99% BroMine between acetophenone 3-bromoacetephenone 3-BROMOACETOPHENONE 98% 3-Bromoacetophenone97% Acetophenone, 3'-bromo- Ethanone, 1-(3-bromophenyl)- M-BROMOACETOPHENONE M-BROMOPHENYL METHYL KETONE BROMOACETOPHENONE-3 1-ACETYL-3-BROMOBENZENE AKOS BBS-00003235 m-Bromoacetophenones 3'-Bromoacetophenone > 3-Bromoacetophenones 3a€-Bromoacetophenone 3-Bromoacetophenone extrapure, 99% M-bromophenone 3-Bromoacetophenone (3BAP) 3'-Bromoacetophenone U-Ring-13C6]-3'-Cyanoacetophenone 3′-Bromoacetophenone, CAS 2142-63-4 1-(3-BROMOPHENYL)ETHAN-1-ONE 1-(3-BROMOPHENYL)ETHANONE 3-BROMOACETOPHENONE 2142-63-4 BrC6H4COCH3 C8H7BrO Organic Building Blocks Ketones Building Blocks C7 to C8 Carbonyl Compounds ARYL HALIDE Building Blocks C7 to C8 Chemical Synthesis Ketones Organic Building Blocks Acetophenone series Bromine Compounds API intermediates Adehydes, Acetals & Ketones Carbonyl Compounds Halides Aromatic Acetophenones & Derivatives (substituted) Benzene series 2142-63-4