3'-Bromoacetophenone
- CAS No.
- 2142-63-4
- Chemical Name:
- 3'-Bromoacetophenone
- Synonyms
- 1-(3-BROMOPHENYL)ETHAN-1-ONE;3-BROMOACETOPHENONE;1-(3-BROMOPHENYL)ETHANONE;M-BROMOACETOPHENONE;NSC 46620;M-bromophenone;AKOS BBS-00003235;3'-Bromacetophenon;3-bromoacetephenone;BROMOACETOPHENONE-3
- CBNumber:
- CB5233225
- Molecular Formula:
- C8H7BrO
- Molecular Weight:
- 199.04
- MDL Number:
- MFCD00000083
- MOL File:
- 2142-63-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3′-Bromoacetophenone ReagentPlus , 99% | B56358 | 25g | $70.3 |
| 3′-Bromoacetophenone ReagentPlus , 99% | B56358 | 100g | $118 |
| 3'-Bromoacetophenone >98.0%(GC) | B0536 | 5g | $17 |
| 3'-Bromoacetophenone >98.0%(GC) | B0536 | 25g | $46 |
| 3'-Bromoacetophenone | TRC-B679363-500MG | 500mg | $59 |
| More product size | |||
| Melting point | 8-11 °C(lit.) |
|---|---|
| Boiling point | 79-81 °C0.2 mm Hg |
| Density | 1.505 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| Water Solubility | Practically insoluble in water |
| form | Liquid |
| Specific Gravity | 1.498 |
| color | Clear slightly yellow to yellow |
| BRN | 507599 |
| InChI | 1S/C8H7BrO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,1H3 |
| InChIKey | JYAQYXOVOHJRCS-UHFFFAOYSA-N |
| SMILES | CC(=O)c1cccc(Br)c1 |
| CAS DataBase Reference | 2142-63-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Bromoacetophenone(2142-63-4) |
| EPA Substance Registry System | Ethanone, 1-(3-bromophenyl)- (2142-63-4) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29147090 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
3'-Bromoacetophenone price More Price(82)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B56358 | 3′-Bromoacetophenone ReagentPlus , 99% | 2142-63-4 | 25g | $70.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | B56358 | 3′-Bromoacetophenone ReagentPlus , 99% | 2142-63-4 | 100g | $118 | 2026-04-30 | Buy |
| TCI Chemical | B0536 | 3'-Bromoacetophenone >98.0%(GC) | 2142-63-4 | 5g | $17 | 2026-04-30 | Buy |
| TCI Chemical | B0536 | 3'-Bromoacetophenone >98.0%(GC) | 2142-63-4 | 25g | $46 | 2026-04-30 | Buy |
| TRC | TRC-B679363-500MG | 3'-Bromoacetophenone | 2142-63-4 | 500mg | $59 | 2026-06-03 | Buy |
3'-Bromoacetophenone Chemical Properties,Uses,Production
Chemical Properties
Clear colourless to light yellow liquid
Uses
3''-Bromoacetophenone is a chemical reagent used in the synthesis of chalcone derivatives as anti-cancer agents. Also used in the preparation of biphenyl pyridazinone deriatives as PDE4 inhibitors in anti-inflammatory treatments.
Synthesis
80ml of 48% hydrobromic acid, 80ml of water and 23g m-amino acetophenone, with ice brine cold to 0 ~ 5 C, and then drop under stirring by 12.2g of sodium nitrite and 30ml of water solution (under the liquid level), and maintain the reaction temperature of 0 ~ 8 C. Drops, and continue to react for 30min. will be made above the diazonium salt solution is poured into the cold CuBr hydrochloric acid solution (27.5 gCuBr + 50 ml hydrobromic acid), heated to 50 ~ 65 , stirred thoroughly for 2 ~ 3h. Separate and remove the solid material and water phase, to obtain the oily material. The oily material was washed with water until the aqueous solution was neutral. The oily material was added to water and distilled with water vapor until there were no oil droplets. Separate the oil layer, the aqueous layer was extracted with benzene, and after combining the oil layers, the benzene was first vaporized at atmospheric pressure, and then distilled at reduced pressure to collect the fraction at 117-122C (2.3 kp), to obtain the product 3'-bromoacetophenone (31.2g, content 99.6%, yield 95.2%).
3'-Bromoacetophenone Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | info@longyupharma.com | China | 2421 | 58 |
View Lastest Price from 3'-Bromoacetophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-21 | 3'-Bromoacetophenone
2142-63-4
|
1KG | ≥99% | 500mt/year | Jinan Finer Chemical Co., Ltd | ||
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2025-06-27 | 3'-Bromoacetophenone
2142-63-4
|
$10.00-30.00 | 50KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-06-20 | 3'-Bromoacetophenone
2142-63-4
|
$10.00-20.00 | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-

- 3'-Bromoacetophenone
2142-63-4
- $0.00
- ≥99%
- Jinan Finer Chemical Co., Ltd
-

- 3'-Bromoacetophenone
2142-63-4
- $10.00-30.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 3'-Bromoacetophenone
2142-63-4
- $10.00-20.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.





