BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER
- CAS No.
- 27383-86-4
- Chemical Name:
- BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER
- Synonyms
- Methyl 2-benzoxazolecarboxylate;Methyl benzo[d]oxazole-2-carboxylate;Methyl 1,3-benzoxazole-2-carboxylate;2-Benzoxazolecarboxylic acid, Methyl ester;BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER
- CBNumber:
- CB52456750
- Molecular Formula:
- C9H7NO3
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD09701312
- MOL File:
- 27383-86-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| METHYL BENZOOXAZOLE-2-CARBOXYLATE 97% | 27062 | 0.25G | $68 |
| METHYL BENZOOXAZOLE-2-CARBOXYLATE 97% | 27062 | 1G | $169 |
| Benzooxazole-2-carboxylic acid methyl ester 97% | OR952861 | 1g | $77 |
| Benzooxazole-2-carboxylic acid methyl ester 97% | OR952861 | 5g | $380 |
| Methyl benzo[d]oxazole-2-carboxylate | 131933 | 250.00mg | $27 |
| More product size | |||
| Melting point | 99 °C |
|---|---|
| Boiling point | 272.3±23.0 °C(Predicted) |
| Density | 1.288±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 0.14±0.10(Predicted) |
| Appearance | White to light brown Solid |
| InChI | InChI=1S/C9H7NO3/c1-12-9(11)8-10-6-4-2-3-5-7(6)13-8/h2-5H,1H3 |
| InChIKey | YDKNBNOOCSNPNS-UHFFFAOYSA-N |
| SMILES | O1C2=CC=CC=C2N=C1C(OC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2934999090 |
BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 27062 | METHYL BENZOOXAZOLE-2-CARBOXYLATE 97% | 27383-86-4 | 0.25G | $68 | 2026-04-30 | Buy |
| AstaTech | 27062 | METHYL BENZOOXAZOLE-2-CARBOXYLATE 97% | 27383-86-4 | 1G | $169 | 2026-04-30 | Buy |
| Apolloscientific | OR952861 | Benzooxazole-2-carboxylic acid methyl ester 97% | 27383-86-4 | 1g | $77 | 2026-06-04 | Buy |
| Apolloscientific | OR952861 | Benzooxazole-2-carboxylic acid methyl ester 97% | 27383-86-4 | 5g | $380 | 2026-06-04 | Buy |
| Matrix Scientific | 131933 | Methyl benzo[d]oxazole-2-carboxylate | 27383-86-4 | 250.00mg | $27 | 2026-05-18 | Buy |
BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Uses,Production
Uses
Methyl Benzo[D]oxazole-2-carboxylate is used as a reactant in the preparation of benzoxazole-based oxadiazoles as antimicrobial agents.
Synthesis
273-53-0
124-38-9
74-88-4
27383-86-4
Catalyst (9.9 mg, 0.025 mmol, 5 mol%), potassium tert-butoxide (0.0672 g, 0.6 mmol) and DMF (3.0 mL) were added to the reaction flask under argon protection. Benzoxazole (50.7 μL, 0.5 mmol) was then added and carbon dioxide gas was passed under atmospheric pressure. The reaction mixture was stirred at 80 °C for 18 hours. After completion of the reaction, the temperature was lowered to 65 °C, iodomethane (93 μL, 1.5 mmol) was added, and stirring was continued at 65 °C for 1 h. The reaction was carried out with the aid of deionized water. At the end of the reaction, the reaction was quenched with deionized water and the reaction product was extracted with ethyl acetate. The yield of the product, methyl benzo[d]oxazole-2-carboxylate, was measured to be 95% by gas chromatography analysis. Further purification by column chromatography using ethyl acetate/petroleum ether (1:10, v/v) as the unfolding solvent gave 90% yield of the purified product.
References
[1] Green Chemistry, 2018, vol. 20, # 5, p. 989 - 996
[2] Organic Letters, 2010, vol. 12, # 15, p. 3567 - 3569
[3] Journal of the American Chemical Society, 2010, vol. 132, # 26, p. 8858 - 8859
[4] Patent: CN106565623, 2017, A. Location in patent: Paragraph 0021
[5] Angewandte Chemie - International Edition, 2010, vol. 49, # 46, p. 8670 - 8673
BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16505 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15058 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9389 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11674 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +86-18327326525 | masar@topule.com | China | 8433 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50110 | 58 | |
| HANGZHOU HAILAN CHEMICAL CO.,LTD. | +86-57156122185 +86-15967590394 | sales@hailan-chem.com | China | 2998 | 58 |
View Lastest Price from BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![METHYL BENZO[D]OXAZOLE-2-CARBOXYLATE pictures](/ProductImageEN1/2025-07/Small/9dabc47b-bc4a-4592-938c-37dc6cca68c8.png) |
2026-07-02 | METHYL BENZO[D]OXAZOLE-2-CARBOXYLATE
27383-86-4
|
$2.00-6.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- METHYL BENZO[D]OXAZOLE-2-CARBOXYLATE
27383-86-4
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
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