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Cinchonidine

CAS No.
485-71-2
Chemical Name:
Cinchonidine
Synonyms
(-)-Cinchonidine;Cinchondine;(8s,9r)-cinchonidine;(8a,9R)-Cinchonan-9-ol;L-Cin;A-QUINIDINE;Cinchovatine;CINCHONIDINE;2'-Hydroxy-4';Chinchonidine
CBNumber:
CB5246395
Molecular Formula:
C19H22N2O
Molecular Weight:
294.39
MDL Number:
MFCD00006783
MOL File:
485-71-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
Cinchonidine 96% C80407 10g $42.2
(-)-Cinchonidine phyproof? Reference Substance PHL80961 100mg $247
Cinchonidine 96% C80407 100g $253
(−)-Cinchonidine analyticalstandard 44703 100mg $45.9
Cinchonidine >98.0%(T) C0347 25g $62
More product size

Cinchonidine Properties

Melting point 204-206 °C(lit.)
alpha -115 º (c=1, EtOH)
Boiling point 436.16°C (rough estimate)
Density 1.0863 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index -107.5 ° (C=1, EtOH)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility 0.25g/l
pka 5.80, 10.03(at 25℃)
form Crystalline Powder
color White to cream
PH 9 (0.2g/l, H2O, 20℃)
optical activity [α]23/D 109.2°, c = 1.5 in ethanol
Water Solubility Insoluble
Sensitive Light Sensitive
Merck 14,2286
BRN 89690
Stability Stable, but light-sensitive. Incompatible with strong oxidizing agents.
InChI 1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14-,18-,19+/m0/s1
InChIKey KMPWYEUPVWOPIM-NAHPKXJFSA-N
SMILES O[C@@H]([C@@H]1C[C@@H]2CCN1C[C@@H]2C=C)c3ccnc4ccccc34
LogP 2.68 at 25℃
CAS DataBase Reference 485-71-2(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1U622LRA8Z
NIST Chemistry Reference Cinchonidine(485-71-2)
EPA Substance Registry System Cinchonan-9-ol, (8.alpha.,9R)- (485-71-2)
UNSPSC Code 12352005
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317-H319
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
PPE Eyeshields, Faceshields, Gloves, type N95 (US)
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-42/43-36/37/38-20/22-48/22-43-22-63
Safety Statements  22-24/25-36/37-36-26
RIDADR  1544
WGK Germany  3
RTECS  GD2975000
TSCA  TSCA listed
HazardClass  6.1(b)
PackingGroup  III
HS Code  29392900
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Sens. 1A
Toxicity LD50 i.p. in rats: 206 mg/kg (Johnson, Poe); LD50 orally in quail: >316 mg/kg (Schafer)
NFPA 704
1
2 1

Cinchonidine price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C80407 Cinchonidine 96% 485-71-2 10g $42.2 2026-04-30 Buy
Sigma-Aldrich PHL80961 (-)-Cinchonidine phyproof? Reference Substance 485-71-2 100mg $247 2026-04-30 Buy
Sigma-Aldrich C80407 Cinchonidine 96% 485-71-2 100g $253 2026-04-30 Buy
Sigma-Aldrich 44703 (−)-Cinchonidine analyticalstandard 485-71-2 100mg $45.9 2021-12-16 Buy
TCI Chemical C0347 Cinchonidine >98.0%(T) 485-71-2 25g $62 2026-04-30 Buy
Product number Packaging Price Buy
C80407 10g $42.2 Buy
PHL80961 100mg $247 Buy
C80407 100g $253 Buy
44703 100mg $45.9 Buy
C0347 25g $62 Buy

Cinchonidine Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

antiamebic, antiprotozoal

Uses

Cinchonidine occurs in most varieties of Cinchona bark and is stereoisomeric with Cinchonine. Cinchonidine exhibits Antimalarial properties.

Definition

ChEBI: 8-epi-Cinchonan in which a hydrogen at position 9 is substituted by hydroxy (R configuration). A diasteroisomer of cinchonine, it occurs in the bark of most varieties of Cinchona shrubs, and is frequently used for directing chirality in asymmetric synthesis.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise cinchonidine from aqueous EtOH. For the N-benzylcinchonidinium chloride see above entry in this section. [Beilstein 23 III/IV 2824.]

Global( 421)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
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+8617392709771 1097@dideu.com China 3996 58
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Hebei shuoxi biotechnology co. LTD
+8613081092107 CHINA 964 58

Related articles

View Lastest Price from Cinchonidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cinchonidine pictures 2026-04-30 Cinchonidine
485-71-2
US $0.00 / KG 1KG 0.99 1000JKG Shaanxi Xianhe Biotech Co., Ltd
Cinchonidine pictures 2026-04-24 Cinchonidine
485-71-2
US $371.00 / KG 1KG 99% 100kg Baoji Guokang Healthchem Co., Ltd.
Cinchonidine pictures 2026-04-22 Cinchonidine
485-71-2
US $44.00 / g 99.64% 10g TargetMol Chemicals Inc.
  • Cinchonidine pictures
  • Cinchonidine
    485-71-2
  • US $0.00 / KG
  • 0.99
  • Shaanxi Xianhe Biotech Co., Ltd
  • Cinchonidine pictures
  • Cinchonidine
    485-71-2
  • US $371.00 / KG
  • 99%
  • Baoji Guokang Healthchem Co., Ltd.
  • Cinchonidine pictures
  • Cinchonidine
    485-71-2
  • US $44.00 / g
  • 99.64%
  • TargetMol Chemicals Inc.
(8-alpha,9r)-cinchonan-9-o (8alpha,9theta)-cinchonan-9-o (8s,9r)-cinchonidine 2-Quinuclidinemethanol, alpha-4-quinolyl-5-vinyl- Cinchonan-9-ol Cinchonan-9-ol, (8alpha,9R)- Cinchovatine Cinchonidinederivedcatalyst {5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)Methanol Cinchonidine, 98.5-101% 100GR Cinchonidine, 98.5-101% 25GR Cinchondine CINCHONIDINE 1-Cinchonidine (-)-Cinchonidine (total base), may cont. up to 5% quinine cinchonidine .base Cinchonidine ,98.5% Cinchonidine,()-Cinchonidine (-)-CINCHONIDINE FOR RESOLUTION OF RACEM (-)-Cinchonidine, 99%, may contain up to 5% quinine (-)-Cinchonidine for resolution of racemates for synthesis (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol (3alpha,4beta,8alpha,9S)-cinchonan-9-ol (3alpha,9R)-9-hydroxycinchonan-1-ium (4beta,8alpha,9R)-cinchonan-1-ium-9-ol (8alpha,9R)-9-hydroxycinchonan-1-ium (9R)-cinchonan-1-ium-9-ol (9R)-cinchonan-9-ol Quinine Sulphate EP Impurity B L-Cin CINCHONAN-9-OL,(8,9R)- A-QUINIDINE ALPHA-QUINIDINE (8alpha,9r)-cinchonan-9-ol CINCHONIDINE: CINCHONAN-9-OL,(8,9R)-, Cinchonidine,99% [8α,9R]-Cinchonan-9-ol Cinchonidine, 98.5-101% CINCHONIDINE(RG) L-CINCHONIDINE Cinchonidine (base and/or unspecified salts) 4-Quinolyl-(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol (R)-Quinolin-4-yl[(2S,4S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-yl]methanol (8S,9R)-Cinchonan-9-ol (-)-Cinchonidine, 99% (total base), may cont. up to 5% quinine (8a,9R)-Cinchonan-9-ol (R)-[(4S,5R,7S)-5-Ethenyl-1-azabicyclo[2.2.2]octan-7-yl]-quinolin-4-ylmethanol Cinchonidine, 98%, for synthesis Cinchonidine > Quinine EP Impurity B (R)-Quinolin-4-yl((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol Cinchonidine USP/EP/BP (-)-Cinchonidine [(2R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol 2'-Hydroxy-4' Cinchonidine (8CI) (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](quinolin-4-yl)methanol (cinchonidine) Chinchonidine