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3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol

CAS No.
1018297-63-6
Chemical Name:
3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol
Synonyms
3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol;3-(4-fluorophenyl)-5-Methyl-4-lsoxazoleMethanol;4-Isoxazolemethanol, 3-(4-fluorophenyl)-5-methyl-;[3-(4-Fluorophenyl)-5-methylisoxazol-4-yl]methanol;(3-(4-Fluorphenyl)-5-methyl-isoxazol-4-yl)-methanol;[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanol
CBNumber:
CB52487529
Molecular Formula:
C11H10FNO2
Molecular Weight:
207.2
MDL Number:
MFCD10008830
MOL File:
1018297-63-6.mol
MSDS File:
SDS
Last updated:2026-05-28 02:02:46

3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol Properties

storage temp. 2-8°C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HS Code  2934999090

3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC200510 [3-(4-Fluorophenyl)-5-methylisoxazol-4-yl]methanol 97% 1018297-63-6 100mg $54 2026-06-04 Buy
Apolloscientific PC200510 [3-(4-Fluorophenyl)-5-methylisoxazol-4-yl]methanol 97% 1018297-63-6 250mg $77 2026-06-04 Buy
Matrix Scientific 207924 [3-(4-Fluorophenyl)-5-methyl-isoxazole-4-yl]methanol 1018297-63-6 1.00g $386 2026-05-18 Buy
Matrix Scientific 207924 [3-(4-Fluorophenyl)-5-methyl-isoxazole-4-yl]methanol 1018297-63-6 5.00g $1520 2026-05-18 Buy
Synthonix F54332 (3-(4-Fluorophenyl)-5-methylisoxazol-4-yl)methanol 97% 1018297-63-6 100mg $280 2026-05-06 Buy
Product number Packaging Price Buy
PC200510 100mg $54 Buy
PC200510 250mg $77 Buy
207924 1.00g $386 Buy
207924 5.00g $1520 Buy
F54332 100mg $280 Buy

3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol Chemical Properties, Uses, Production

Synthesis

3-(4-FLUORO-PHENYL)-5-METHYL-ISOXAZOLE-4-CARBOXYLIC ACID ETHYL ESTER

954230-39-8

3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol

1018297-63-6

GENERAL STEPS: To a suspension of LiAlH4 (75.9 mg, 2.0 mmol) in THF (2 mL) was added a solution of ethyl 3-(4-fluorophenyl)-5-methylisoxazole-4-carboxylate (0.50 g, 2.0 mmol) in THF (3 mL) dropwise over a period of 15 min at 0-10 °C. The reaction mixture was gradually warmed up to room temperature and stirred continuously at this temperature for at least 1 hour. Upon completion of the reaction, the reaction was quenched by the slow addition of water (15 mL), the resulting suspension was filtered and the filter cake was washed with ethyl acetate (15 mL). The organic and aqueous layers of the filtrate were separated and the organic layer was washed once with water (15 mL). The aqueous layers were combined and back-extracted with ethyl acetate (2 x 15 mL). All organic layers were combined, dried with anhydrous Na2SO4 and subsequently concentrated to dryness under reduced pressure at 45 °C/25 mbar to give 0.375 g (90% yield) of 3-(4-fluorophenyl)-5-methyl-4-isoxazole methanol as a light yellow solid, and HPLC analysis showed 100% purity.

References

[1] Patent: US2013/102778, 2013, A1. Location in patent: Paragraph 0223; 0224
[2] Patent: US2009/143385, 2009, A1
[3] Patent: WO2013/57124, 2013, A1. Location in patent: Page/Page column 33
[4] Patent: US2013/172329, 2013, A1. Location in patent: Paragraph 0245
[5] Patent: EP2792360, 2014, A1. Location in patent: Paragraph 0168

3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol Preparation Products And Raw materials

Global Suppliers ( 45)
Supplier Tel Email Country ProdList Advantage
Taizhou Tongxin Bio-Tech Co., Ltd 0523-86818997 18652728585 sales@allyrise.com China 2986 60
Shanghai YuLue Chemical Co., Ltd. 021-60345187 13671753212 lzz841106@aliyun.com China 10244 55
Shanghai XinKai Chemical Technology Co., Ltd. 021-58930698 15921516558 zhangyichao84@126.com China 979 55
Shanghai XR Chemical Technology Co., Ltd. 021-31007982 18019432809; info@xrpharma.com China 686 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Taian Jiaye Biotechnology Co.Ltd 15318151873;13127280945 285424065@qq.com China 9961 55
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
Yujinpharma(Tianjin) Technology Co.,Ltd. 13370351217 kungfu1217@1 kungfu1217@163.com China 7991 58
Labnetwork lnc. +86-27-50766799 +86-18062016861 contact@labnetwork.com China 19981 58
Chemwill Asia Co.,Ltd. 86-21-51086038 chemwill_asia@126.com CHINA 23861 58

View Latest Price from 3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol pictures 2019-07-06 3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol
1018297-63-6
$2.00 1KG 99% Career Henan Chemical Co
3-(4-fluorophenyl)-5-Methyl-4-IsoxazoleMethanol [3-(4-Fluorophenyl)-5-methylisoxazol-4-yl]methanol 4-Isoxazolemethanol, 3-(4-fluorophenyl)-5-methyl- [3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methanol 3-(4-fluorophenyl)-5-Methyl-4-lsoxazoleMethanol (3-(4-Fluorphenyl)-5-methyl-isoxazol-4-yl)-methanol 1018297-63-6