Nsc21187
- CAS No.
- 87932-49-8
- Chemical Name:
- Nsc21187
- Synonyms
- Nsc21187;3-chloro-4,5-dihydroxybenzoic acid;Benzoic acid, 3-chloro-4,5-dihydroxy-
- CBNumber:
- CB52492279
- Molecular Formula:
- C7H5ClO4
- Molecular Weight:
- 188.57
- MDL Number:
- MFCD01742816
- MOL File:
- 87932-49-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-CHLORO-4,5-DIHYDROXYBENZOICACID | 2705AQ | 500mg | $390.8 |
| 3-Chloro-4,5-dihydroxybenzoicacid 95+% | CD12020141 | 5g | $792 |
| 3-chloro-4,5-dihydroxybenzoicacid 95% | CM132886 | 5g | $982 |
| 3-Chloro-4,5-dihydroxybenzoicacid | 87932498 | 5g | $1050 |
| 3-Chloro-4,5-dihydroxybenzoicacid 95+% | CD12020141 | 10g | $1485 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Nsc21187 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AK Scientific | 2705AQ | 3-CHLORO-4,5-DIHYDROXYBENZOICACID | 87932-49-8 | 500mg | $390.8 | 2021-12-16 | Buy |
| Crysdot | CD12020141 | 3-Chloro-4,5-dihydroxybenzoicacid 95+% | 87932-49-8 | 5g | $792 | 2021-12-16 | Buy |
| Chemenu | CM132886 | 3-chloro-4,5-dihydroxybenzoicacid 95% | 87932-49-8 | 5g | $982 | 2021-12-16 | Buy |
| Alichem | 87932498 | 3-Chloro-4,5-dihydroxybenzoicacid | 87932-49-8 | 5g | $1050 | 2021-12-16 | Buy |
| Crysdot | CD12020141 | 3-Chloro-4,5-dihydroxybenzoicacid 95+% | 87932-49-8 | 10g | $1485 | 2021-12-16 | Buy |
Nsc21187 Chemical Properties,Uses,Production
Synthesis
62936-23-6
87932-49-8
General procedure for the synthesis of 3-chloro-4,5-dihydroxybenzoic acid from 3-chloro-4-hydroxy-5-methoxybenzoic acid: Step (i): tribromoborane (7.86 mL, 82 mmol) was added dropwise to a stirred solution of 3-chloro-4-hydroxy-5-methoxybenzoic acid (6.61 g, 32.6 mmol) in dichloromethane (50 mL) under nitrogen protection. The reaction mixture was continued to be stirred at 0 °C for 2 h and subsequently poured in batches into ice/brine (250 mL). The aqueous phase was extracted with ethyl acetate (2 x 150 mL) and the combined organic phases were dried over magnesium sulfate and filtered. The solvent was removed by concentration under reduced pressure to give 3-chloro-4,5-dihydroxybenzoic acid (5.11 g, 79% yield). Mass spectrum (electrospray ionization, negative mode) m/z 187 [M-H] ; 1H NMR (400 MHz, DMSO-d) δ: 12.69 (1H, broad single peak), 10.14 (2H, broad single peak), 7.35 (1H, double peak), 7.32 (1H, double peak).
References
[1] Patent: WO2011/27106, 2011, A1. Location in patent: Page/Page column 106-107
[2] Patent: US2012/149737, 2012, A1. Location in patent: Page/Page column 58
[3] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 4, p. 798 - 814
Nsc21187 Preparation Products And Raw materials
Nsc21187 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| BeiJing Hwrk Chemicals Limted | 0757-86329057 18934348241 | sales4.gd@hwrkchemical.com | China | 14063 | 55 |
| Shanghai Litong Chemical Technology Co.,Ltd. | 13598610367 0373-7129549 | 2468833170@qq.com | China | 932 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 88915 | 60 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Aikon International Limited | 025-58859352 15955137747 | sales01@aikonchem.com | China | 16027 | 58 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13482353728 | sales@fdc-chemical.com | China | 9965 | 58 |
| Zhengzhou Alpha Chemical Co. LTD | 0371-53732842 13383863444 | 3838551451@qq.com | China | 9992 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
