N-Cbz-2-Amino-1,3-propanediol
- CAS No.
- 71811-26-2
- Chemical Name:
- N-Cbz-2-Amino-1,3-propanediol
- Synonyms
- N-Cbz-Serinol;N-Cbz-2-amino-1,3-propyldiol;N-Cbz-2-Amino-1,3-propanediol;Carbamic acid, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-, phenylmethyl ester
- CBNumber:
- CB52500848
- Molecular Formula:
- C11H15NO4
- Molecular Weight:
- 225.24
- MDL Number:
- MFCD11656821
- MOL File:
- 71811-26-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| N-Cbz-2-Amino-1,3-propanediol 97% | AS21600 | 1g | $29 |
| N-Cbz-2-Amino-1,3-propanediol 97% | AS21600 | 5g | $84 |
| N-Cbz-2-Amino-1,3-propanediol 97% | AS21600 | 25g | $157 |
| Benzyl (1,3-dihydroxypropan-2-yl)carbamate 97% | A121899 | 250mg | $10 |
| Benzyl (1,3-dihydroxypropan-2-yl)carbamate 97% | A121899 | 1g | $12 |
| More product size | |||
| Melting point | 110.3-112.2 °C |
|---|---|
| Boiling point | 457.644±45.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.255±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 11.388±0.46(predicted) |
| Appearance | White to off-white Solid |
N-Cbz-2-Amino-1,3-propanediol price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS21600 | N-Cbz-2-Amino-1,3-propanediol 97% | 71811-26-2 | 1g | $29 | 2026-06-04 | Buy |
| Activate Scientific | AS21600 | N-Cbz-2-Amino-1,3-propanediol 97% | 71811-26-2 | 5g | $84 | 2026-06-04 | Buy |
| Activate Scientific | AS21600 | N-Cbz-2-Amino-1,3-propanediol 97% | 71811-26-2 | 25g | $157 | 2026-06-04 | Buy |
| Ambeed | A121899 | Benzyl (1,3-dihydroxypropan-2-yl)carbamate 97% | 71811-26-2 | 250mg | $10 | 2026-06-05 | Buy |
| Ambeed | A121899 | Benzyl (1,3-dihydroxypropan-2-yl)carbamate 97% | 71811-26-2 | 1g | $12 | 2026-06-05 | Buy |
N-Cbz-2-Amino-1,3-propanediol Chemical Properties,Uses,Production
Synthesis
501-53-1
71811-26-2
General procedure for the synthesis of benzyl (1,3-dihydroxypropan-2-yl) carbamate from benzyl chloroformate: to a stirred slurry of 1.00 g (4.24 mmol) of N-benzyloxycarbonyl-1,3-dihydroxy-2-aminopropane and 0.65 mL (4.7 mmol) of triethylamine in 10 mL of THF at 0°C under argon gas protection over a 10-minute period 0.6 mL (4.2 mmol) of benzyl chloroformate (Aldrich) was slowly added dropwise. The reaction mixture was gradually warmed to room temperature and stirred continuously for 14 hours. After completion of the reaction, the mixture was diluted with ether and filtered. The filtrate was concentrated by evaporation and the residue was dissolved in 25 mL of methanol, 2 drops of dioxane solution with 4N HCl were added and the solution was heated to 40°C and maintained for 30 minutes. The solvent was subsequently evaporated and the residue was ground with a hexane/ether solvent mixture to give benzyl (1,3-dihydroxypropan-2-yl)carbamate as a white solid in 92% yield (880 mg) with a melting point of 104-106 °C. The mass spectrum (electrospray, positive ion mode) showed a m/z of 226.
References
[1] Patent: US5962440, 1999, A
N-Cbz-2-Amino-1,3-propanediol Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49859 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3279 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| ITIC MEDCHEM(SUZHOU) CO.,LTD. | 0512-68323967 18015559028 | sales@iticmedchem.com | China | 526 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
