DISIALOGANGLIOSIDE GD1B 2NA
- CAS No.
- 19553-76-5
- Chemical Name:
- DISIALOGANGLIOSIDE GD1B 2NA
- Synonyms
- Gd1b;GD1B 2NA;Aids002546;Aids-002546;Ganglioside G2;Ganglioside C1;Ganglioside giii;GD1B-GANGLIOSIDE;GD1B (NH4+ SALT);ganglioside, GD1b
- CBNumber:
- CB5253296
- Molecular Formula:
- C84H148N4O40
- Molecular Weight:
- 1854.08
- MDL Number:
- MFCD00466941
- MOL File:
- 19553-76-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Disialoganglioside GD1b from bovine brain ~95% | G8146 | 1mg | $345 |
| Ganglioside GD1b (bovine) (sodium salt) ≥98% | 34778 | 1mg | $164 |
| Ganglioside GD1b (bovine) (sodium salt) ≥98% | 34778 | 5mg | $612 |
| Ganglioside GD1b (bovine) (ammonium salt) ≥98% | 31708 | 1mg | $156 |
| Ganglioside GD1b (bovine) (ammonium salt) ≥98% | 31708 | 5mg | $614 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HS Code | 29400090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
DISIALOGANGLIOSIDE GD1B 2NA price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | G8146 | Disialoganglioside GD1b from bovine brain ~95% | 19553-76-5 | 1mg | $345 | 2026-04-30 | Buy |
| Cayman Chemical | 34778 | Ganglioside GD1b (bovine) (sodium salt) ≥98% | 19553-76-5 | 1mg | $164 | 2026-04-30 | Buy |
| Cayman Chemical | 34778 | Ganglioside GD1b (bovine) (sodium salt) ≥98% | 19553-76-5 | 5mg | $612 | 2026-04-30 | Buy |
| Cayman Chemical | 31708 | Ganglioside GD1b (bovine) (ammonium salt) ≥98% | 19553-76-5 | 1mg | $156 | 2026-04-30 | Buy |
| Cayman Chemical | 31708 | Ganglioside GD1b (bovine) (ammonium salt) ≥98% | 19553-76-5 | 5mg | $614 | 2026-04-30 | Buy |
DISIALOGANGLIOSIDE GD1B 2NA Chemical Properties,Uses,Production
Description
Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas. Ganglioside GD1b mixture contains ganglioside GD1b molecular species with C18:1 and C20:1 fatty acyl chains.
Uses
Ganglioside GD1b Disodium Salt (Bovine Brain) is a ganglioside, major constituents of neuronal cell membranes and endoplasmic reticulum that have been shown to modulate cell signal transduction.
General Description
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
Biochem/physiol Actions
May act as a bacterial toxin receptor (tetanus, botulinus); high levels found in gliomas and astrocytomas.
References
[1] L RIBONI. Natural occurrence of ganglioside lactones. Isolation and characterization of GD1b inner ester from adult human brain.[J]. The Journal of Biological Chemistry, 1986, 261 18: 8514-8519.
[2] T. COMAS. Immunohistochemical staining for ganglioside GD1b as a diagnostic and prognostic marker for primary human brain tumors.[J]. Neuro-oncology, 1999, 1 4 1: 261-267. DOI: 10.1093/neuonc/1.4.261
DISIALOGANGLIOSIDE GD1B 2NA Preparation Products And Raw materials
Raw materials
Preparation Products
DISIALOGANGLIOSIDE GD1B 2NA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GlycoPharm.LLC | +86-27-63498076 | sale@glycolipidpharm.com | CHINA | 158 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Watson Biotechnology Co.,Ltd | +86-18186686046 +86-18186686046; | sales01@watsonbiotech.cn | China | 5733 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3988 | 66 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9804 | 58 |
View Lastest Price from DISIALOGANGLIOSIDE GD1B 2NA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-22 | Ganglioside GD1b Mixture (sodium salt)
19553-76-5
|
10g | TargetMol Chemicals Inc. | ||||
 |
2020-03-26 | Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide Synonym:?GD1b
19553-76-5
|
5test | 97%HPLC | GlycoPharm.LLC |
-
- Ganglioside GD1b Mixture (sodium salt)
19553-76-5
- $0.00
- TargetMol Chemicals Inc.
-
- Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide Synonym:?GD1b
19553-76-5
- $0.00
- 97%HPLC
- GlycoPharm.LLC
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