ChemicalBook >> CAS DataBase List >>(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone

(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone

(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone structure

CAS No.: 135635-46-0

Chemical Name:: (E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone

Synonyms: TacroliMus Related CoMpound A;Tacrolimus Related Compound A DISCONTINUED, See A781000;Tacrolimus Impurity 38 (Tacrolimus USP Related Compound A );Tacrolimus Related Compound A (15 mg) (See USP Certificate for full Chemical Name);Tacrolimus Related Compound A (See USP Certificate for full Chemical Name) (1642813);Tacrolimus Related Compound AQ: What is Tacrolimus Related Compound A Q: What is the CAS Number of Tacrolimus Related Compound A;(E)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyr;(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-Chemicalbook13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,;(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone;8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

CBNumber:: CB52542167

Molecular Formula:: C43H69NO12

Molecular Weight:: 792.01

MDL Number:: MFCD28369379

MOL File:: 135635-46-0.mol

MSDS File:: SDS

Last updated:2026-07-28 08:09:38

Product description	Number	Pack Size	Price
(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone	AA009GA0	15mg	$1373
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(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone Properties

Boiling point	868.314±75.00 °C(Press: 760.00 Torr)(predicted)
Density	1.197±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp.	-10 to -25°C
pka	9.964±0.70(predicted)
Major Application	pharmaceutical (small molecule)
InChIKey	ZDQSOHOQTUFQEM-MKSXAWMCSA-N
SMILES	O1C(C(C)=CC2CCC(O)C(OC)C2)C(C)C(O)CC(=O)C(CC)C=C(C)CC(C)CC(OC)C2OC(O)(C(C)CC2OC)C(=O)C(=O)N2CCCCC2C1=O \|c:25\|
FDA UNII	AUF4U5NSJK
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H373
Precautionary statements	P260
target organs	Immune system
WGK Germany	WGK 3
HS Code	2934990002
Storage Class	11 - Combustible Solids
Hazard Classifications	STOT RE 2

(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA009GA0	(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone	135635-46-0	15mg	$1373	2026-05-28	Buy

Product number	Packaging	Price	Buy
AA009GA0	15mg	$1373	Buy

(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone Chemical Properties,Uses,Production

Uses

Tacrolimus Related Compound A USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Definition

ChEBI: Ascomycin is a macrolide that is produced by the fermentation of Streptomyces hygroscopicus and exhibits strong immunosuppressant properties. It has a role as an immunosuppressive agent, an antifungal agent and a bacterial metabolite. It is a macrolide, an ether, a lactol and a secondary alcohol.

(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone Suppliers

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Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
QUALITY CONTROL SOLUTIONS LTD.	+86-0755-66853366 +86-13670046396	export03@qcsrm.com	China	24318	58
Changsha Fuzhen Biotechnology Co.，LTD	15111215862 18229892877	3062105966@qq.com	China	5550	58
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
Shenzhen SUNGENING Bio-Medical Co., Ltd.	0755-28967200 13631290199	wxf@sungening.com	China	9609	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	57336	58
Hefei fuya biotechnology co. LTD	18096409024	sales02@foreversyn.com	China	1930	58
Changzhou Xianglong Pharmaceutical Technology Co., LTD	18661161657	sales@xianglongpharm.com	China	10000	58
Cato Research Chemicals Inc.	020-81960175-877 18933936954	tianwen.zhan@cato-chem.com	China	7335	58
Shanghai Easy CDMO Co.,Ltd	Info@easycdmo.com 13564957716	Info@easycdmo.com	China	9999	58

Supplier	Advantage
Career Henan Chemica Co	58
QUALITY CONTROL SOLUTIONS LTD.	58
Changsha Fuzhen Biotechnology Co.，LTD	58
Quality Control Solutions Ltd.	56
Shenzhen SUNGENING Bio-Medical Co., Ltd.	60
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Hefei fuya biotechnology co. LTD	58
Changzhou Xianglong Pharmaceutical Technology Co., LTD	58
Cato Research Chemicals Inc.	58
Shanghai Easy CDMO Co.,Ltd	58

135635-46-0((E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone)Related Search:

Tacrolimus

(E)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21-(4H,23H)-tetrone Tacrolimus Related Compound A (15 mg) (See USP Certificate for full Chemical Name) (E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3,10,16-tetrone TacroliMus Related CoMpound A 8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone (E)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyr 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl- Tacrolimus Related Compound A DISCONTINUED, See A781000 Tacrolimus Related Compound AQ: What is Tacrolimus Related Compound A Q: What is the CAS Number of Tacrolimus Related Compound A Tacrolimus Related Compound A (See USP Certificate for full Chemical Name) (1642813) Tacrolimus Impurity 38 (Tacrolimus USP Related Compound A ) (E)-17-ethyl-1,14-dihydroxy-12[(E)-2-(4-hydroxy-3-Methoxycyclohexyl)-1-Methylvinyl]-23,25-diMethoxy-Chemicalbook13,19,21,27-tetraMethyl-11,28-dioxa-4-azatricyclo[22.3.1.0(super4,9)]octacos-18-ene-2,3, 135635-46-0